Magnetic resonance imaging-guided intracranial resection of glioblastoma tumors in patient-derived orthotopic xenografts leads to clinically relevant tumor recurrence von Anais Oudin, Pilar M. Moreno-Sanchez, Virginie Baus, Simone P. Niclou, Anna Golebiewska

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Glioblastoma Organoids: Pre-Clinical Applications and Challenges in the Context of Immunotherapy von Eliane Klein, Ann-Christin Hau, Anaïs Oudin, Anna Golebiewska, Simone P. Niclou, Simone P. Niclou

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The BET Protein Inhibitor JQ1 Decreases Hypoxia and Improves the Therapeutic Benefit of Anti-PD-1 in a High-Risk Neuroblastoma Mouse Model von Delphine Sauvage, Manon Bosseler, Elodie Viry, Georgia Kanli, Anais Oudin, Guy Berchem, Olivier Keunen, Bassam Janji

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Protocol using ex vivo mouse brain slice culture mimicking in vivo conditions to study tumor growth and cell motility of glioblastoma cells von Laura Neises, Catherine Delbrouck, Anne Schuster, Mahsa Rezaipour, Kim Eiden, Anais Oudin, Carina Fabian, Simone P. Niclou, Anna Golebiewska, Johannes Meiser

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P598: DISRUPTION IN ONE-CARBON METABOLISM THROUGH MTHFD1 INHIBITION AS NOVEL THERAPEUTIC STRATEGY IN CHRONIC LYMPHOCYTIC LEUKEMIA von Elodie Viry, Chloé Duculty, Nicole Kiweler, Coralie Pulido, Anais Oudin, Ana Slipicevic, Martin Henriksson, Johannes Meise, Thomas Helleday, Etienne Moussay, Jérôme Paggetti

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Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma. von Morgane Sanzey, Siti Aminah Abdul Rahim, Anais Oudin, Anne Dirkse, Tony Kaoma, Laurent Vallar, Christel Herold-Mende, Rolf Bjerkvig, Anna Golebiewska, Simone P Niclou

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Adenoviral delivery of the CIITA transgene induces T‐cell‐mediated killing in glioblastoma organoids von Ilaria Salvato, Eliane Klein, Aurélie Poli, Mahsa Rezaeipour, Luca Ermini, Bakhtiyor Nosirov, Anuja Lipsa, Anaïs Oudin, Virginie Baus, Gian Mario Dore, Antonio Cosma, Anna Golebiewska, Antonio Marchini, Simone P. Niclou

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Elucidating tumour‐associated microglia/macrophage diversity along glioblastoma progression and under ACOD1 deficiency von Yolanda Pires‐Afonso, Arnaud Muller, Kamil Grzyb, Anaïs Oudin, Yahaya A. Yabo, Carole Sousa, Andrea Scafidi, Aurélie Poli, Antonio Cosma, Rashi Halder, Djalil Coowar, Anna Golebiewska, Alexander Skupin, Simone P. Niclou, Alessandro Michelucci

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Protocol for derivation of organoids and patient-derived orthotopic xenografts from glioma patient tumors von Anaïs Oudin, Virginie Baus, Vanessa Barthelemy, Carina Fabian, Eliane Klein, Monika Dieterle, May Wantz, Ann-Christin Hau, Claire Dording, Amandine Bernard, Alessandro Michelucci, Yahaya A. Yabo, Georgia Kanli, Olivier Keunen, Rolf Bjerkvig, Simone P. Niclou, Anna Golebiewska

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Altered metabolic landscape in IDH‐mutant gliomas affects phospholipid, energy, and oxidative stress pathways von Fred Fack, Saverio Tardito, Guillaume Hochart, Anais Oudin, Liang Zheng, Sabrina Fritah, Anna Golebiewska, Petr V Nazarov, Amandine Bernard, Ann‐Christin Hau, Olivier Keunen, William Leenders, Morten Lund‐Johansen, Jonathan Stauber, Eyal Gottlieb, Rolf Bjerkvig, Simone P Niclou

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AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion von Anne Schuster, Eliane Klein, Virginie Neirinckx, Arnon Møldrup Knudsen, Carina Fabian, Ann-Christin Hau, Monika Dieterle, Anais Oudin, Petr V. Nazarov, Anna Golebiewska, Arnaud Muller, Daniel Perez-Hernandez, Sophie Rodius, Gunnar Dittmar, Rolf Bjerkvig, Christel Herold-Mende, Barbara Klink, Bjarne Winther Kristensen, Simone P. Niclou

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PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle von Mohaned Benzarti, Laura Neises, Anais Oudin, Christina Krötz, Elodie Viry, Ernesto Gargiulo, Coralie Pulido, Maryse Schmoetten, Vitaly Pozdeev, Nadia I. Lorenz, Michael W. Ronellenfitsch, David Sumpton, Marc Warmoes, Christian Jaeger, Antoine Lesur, Björn Becker, Etienne Moussay, Jerome Paggetti, Simone P. Niclou, Elisabeth Letellier, Johannes Meiser

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Formate promotes invasion and metastasis in reliance on lipid metabolism von Catherine Delbrouck, Nicole Kiweler, Oleg Chen, Vitaly I. Pozdeev, Lara Haase, Laura Neises, Anaïs Oudin, Aymeric Fouquier d’Hérouël, Ruolin Shen, Lisa Schlicker, Rashi Halder, Antoine Lesur, Anne Schuster, Nadja I. Lorenz, Christian Jaeger, Maureen Feucherolles, Gilles Frache, Martyna Szpakowska, Andy Chevigne, Michael W. Ronellenfitsch, Etienne Moussay, Marie Piraud, Alexander Skupin, Almut Schulze, Simone P. Niclou, Elisabeth Letellier, Johannes Meiser

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Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xe... von Yahaya A. Yabo, Pilar M. Moreno-Sanchez, Yolanda Pires-Afonso, Tony Kaoma, Bakhtiyor Nosirov, Andrea Scafidi, Luca Ermini, Anuja Lipsa, Anaïs Oudin, Dimitrios Kyriakis, Kamil Grzyb, Suresh K. Poovathingal, Aurélie Poli, Arnaud Muller, Reka Toth, Barbara Klink, Guy Berchem, Christophe Berthold, Frank Hertel, Michel Mittelbronn, Dieter H. Heiland, Alexander Skupin, Petr V. Nazarov, Simone P. Niclou, Alessandro Michelucci, Anna Golebiewska

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