A Novel Breakthrough in Leptospira spp. Mutagenesis: Knockout by Combination of CRISPR/Cas9 and Non-homologous End-Joining Systems by Luis G. V. Fernandes, Ana L. T. O. Nascimento, Ana L. T. O. Nascimento

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Evaluation of Leptospira interrogans knockdown mutants for LipL32, LipL41, LipL21, and OmpL1 proteins by Luis G. V. Fernandes, Aline F. Teixeira, Ana L. T. O. Nascimento, Ana L. T. O. Nascimento

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In silico analysis and functional characterization of a leucine-rich repeat protein of Leptospira interrogans by João P. Gaspar, Maria B. Takahashi, Aline F. Teixeira, Ana L.T.O. Nascimento

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LIC12254 Is a Leptospiral Protein That Interacts with Integrins via the RGD Motif by Maria F. Cavenague, Aline F. Teixeira, Luis G. V. Fernandes, Ana L. T. O. Nascimento

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Evaluation of binding activities of a putative lipoprotein LIC_13355 of Leptospira spp. by Igor R. M. Silva, Maria B. Takahashi, Aline F. Teixeira, Ana L. T. O. Nascimento

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Characterization of novel OmpA-like protein of Leptospira interrogans that binds extracellular matrix molecules and plasminogen. by Rosane Oliveira, Zenaide Maria de Morais, Amane Paldes Gonçales, Eliete Caló Romero, Silvio Arruda Vasconcellos, Ana L T O Nascimento

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A New Recombinant Multiepitope Chimeric Protein of <i>Leptospira interrogans</i> Is a Promising Marker for the Serodiagnosis of Leptospirosis by Luis G. V. Fernandes, Kátia E. S. Avelar, Eliete C. Romero, Marcos B. Heinemann, Karin Kirchgatter, Ana L. T. O. Nascimento

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Leucine-rich repeat proteins of Leptospira interrogans that interact to host glycosaminoglycans and integrins by Bruno B. Foltran, Bruno B. Foltran, Aline F. Teixeira, Eliete C. Romero, Luis G. V. Fernandes, Ana L. T. O. Nascimento

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Revisiting the Development of Vaccines Against Pathogenic Leptospira: Innovative Approaches, Present Challenges, and Future Perspectives by Giovana C. Barazzone, Giovana C. Barazzone, Aline F. Teixeira, Bruna O. P. Azevedo, Bruna O. P. Azevedo, Deborah K. Damiano, Deborah K. Damiano, Marcos P. Oliveira, Marcos P. Oliveira, Ana L. T. O. Nascimento, Ana L. T. O. Nascimento, Alexandre P. Y. Lopes, Alexandre P. Y. Lopes

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Development of transcriptional fusions to assess Leptospira interrogans promoter activity. by Gustavo M Cerqueira, Natalie M Souza, Eduardo R Araújo, Aline T Barros, Zenaide M Morais, Sílvio A Vasconcellos, Ana L T O Nascimento

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<i>In Silico</i> Analysis of Genetic VapC Profiles from the Toxin-Antitoxin Type II VapBC Modules among Pathogenic, Intermediate, and Non-Pathogenic <i>Leptospira</i> by Alexandre P. Y. Lopes, Bruna O. P. Azevedo, Rebeca C. Emídio, Deborah K. Damiano, Ana L. T. O. Nascimento, Giovana C. Barazzone

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In vitro identification of novel plasminogen-binding receptors of the pathogen Leptospira interrogans. by Monica L Vieira, Marina V Atzingen, Tatiane R Oliveira, Rosane Oliveira, Daniel M Andrade, Silvio A Vasconcellos, Ana L T O Nascimento

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Evaluation of LipL32 and LigA/LigB Knockdown Mutants in Leptospira interrogans Serovar Copenhageni: Impacts to Proteome and Virulence by Luis G. V. Fernandes, Luis G. V. Fernandes, Ellie J. Putz, Judith Stasko, John D. Lippolis, Ana L. T. O. Nascimento, Jarlath E. Nally

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Bioinformatics describes novel Loci for high resolution discrimination of leptospira isolates. by Gustavo M Cerqueira, Alan J A McBride, Rudy A Hartskeerl, Niyaz Ahmed, Odir A Dellagostin, Marcus R Eslabão, Ana L T O Nascimento

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A Review on Host-Leptospira Interactions: What We Know and Future Expectations by Brenda B. Daroz, Brenda B. Daroz, Luis G. V. Fernandes, Maria F. Cavenague, Maria F. Cavenague, Leandro T. Kochi, Leandro T. Kochi, Felipe J. Passalia, Felipe J. Passalia, Maria B. Takahashi, Maria B. Takahashi, Edson G. Nascimento Filho, Edson G. Nascimento Filho, Aline F. Teixeira, Ana L. T. O. Nascimento, Ana L. T. O. Nascimento

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The interaction of two novel putative proteins of Leptospira interrogans with E-cadherin, plasminogen and complement components with potential role in bacterial infection by Leandro T. Kochi, Luis G. V. Fernandes, Gisele O. Souza, Silvio A. Vasconcellos, Marcos B. Heinemann, Eliete C. Romero, Karin Kirchgatter, Ana L. T. O. Nascimento

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The Toxin of VapBC-1 Toxin-Antitoxin Module from <i>Leptospira interrogans</i> Is a Ribonuclease That Does Not Arrest Bacterial Growth but Affects Cell Viability by Deborah K. Damiano, Bruna O. P. Azevedo, George S. C. Fernandes, Aline F. Teixeira, Viviane M. Gonçalves, Ana L. T. O. Nascimento, Alexandre P. Y. Lopes

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Immune response and protective profile elicited by a multi-epitope chimeric protein derived from Leptospira interrogans by Luis G.V. Fernandes, Aline F. Teixeira, Antonio F.S. Filho, Gisele O. Souza, Silvio A. Vasconcellos, Marcos B. Heinemann, Eliete C. Romero, Ana L.T.O. Nascimento

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Adhesins of Leptospira interrogans mediate the interaction to fibrinogen and inhibit fibrin clot formation in vitro. by Rosane Oliveira, Renan F Domingos, Gabriela H Siqueira, Luis G Fernandes, Natalie M Souza, Monica L Vieira, Zenaide M de Morais, Silvio A Vasconcellos, Ana L T O Nascimento

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Immunoprotective Activity Induced by Leptospiral Outer Membrane Proteins in Hamster Model of Acute Leptospirosis by Aline F. Teixeira, Maria F. Cavenague, Maria F. Cavenague, Leandro T. Kochi, Leandro T. Kochi, Luis G. Fernandes, Gisele O. Souza, Antonio Francisco de Souza Filho, Silvio A. Vasconcellos, Marcos Bryan Heinemann, Ana L. T. O. Nascimento

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