The Secondary Myelodysplastic Neoplasms (MDS) Jigsaw by Oriol Calvete, Julia Mestre, Andrés Jerez, Francesc Solé

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Persistent Large Granular Lymphocyte Clonal Expansions: “The Root of Many Evils”—And of Some Goodness by Carlos Bravo-Pérez, Salvador Carrillo-Tornel, Esmeralda García-Torralba, Andrés Jerez

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Minimal Residual Disease in Multiple Myeloma: Something Old, Something New by Carlos Bravo-Pérez, María Sola, Raúl Teruel-Montoya, María Dolores García-Malo, Francisco José Ortuño, Vicente Vicente, Felipe de Arriba, Andrés Jerez

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P720: A BONE MARROW MICROENVIRONMENTAL CELL SIGNATURE SCORING SYSTEM INDEPENDENTLY PREDICTED SURVIVAL AND DRUG RESISTANCE IN CHRONIC MYELOMONOCYTIC LEUKAEMIA PATIENTS by Yu-Hung Wang, Kristian Gurashi, Chien-Chin Lin, Chi-Yuan Yao, Fabio M. R. Amaral, Andres Jerez, Tim C. P. Somervaille, Hsin-An Hou, Wen Chien Chou, Kiran Batta, Daniel Wiseman, Hwei-Fang Tien

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Myeloid Malignancies with Chromosome 5q Deletions Acquire a Dependency on an Intrachromosomal NF-κB Gene Network by Jing Fang, Brenden Barker, Lyndsey Bolanos, Xiaona Liu, Andres Jerez, Hideki Makishima, Susanne Christie, Xiaoting Chen, Dinesh S. Rao, H. Leighton Grimes, Kakajan Komurov, Matthew T. Weirauch, Jose A. Cancelas, Jaroslaw P. Maciejewski, Daniel T. Starczynowski

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GWAS-Identified Variants for Obesity Do Not Influence the Risk of Developing Multiple Myeloma: A Population-Based Study and Meta-Analysis by José Manuel Sánchez-Maldonado, Antonio José Cabrera-Serrano, Subhayan Chattopadhyay, Daniele Campa, María del Pilar Garrido, Angelica Macauda, Rob Ter Horst, Andrés Jerez, Mihai G. Netea, Yang Li, Kari Hemminki, Federico Canzian, Asta Försti, Juan Sainz

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Cancer testis antigens in myelodysplastic syndromes revisited: a targeted RNA-seq approach by Ana María Hurtado López, Tzu Hua Chen-Liang, María Zurdo, Salvador Carrillo-Tornel, Joaquín Panadero, Eduardo José Salido, Victor Beltrán, Begoña Muiña, MariLuz Amigo, Noelia Navarro-Villamor, Rosa Cifuentes, Inés Calabria, Ana Isabel Antón, Raúl Teruel, Manuel Muro, Vicente Vicente, Andrés Jerez

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Trisomy 8, a Cytogenetic Abnormality in Myelodysplastic Syndromes, Is Constitutional or Not? by Sílvia Saumell, Francesc Solé, Leonor Arenillas, Julia Montoro, David Valcárcel, Carme Pedro, Carmen Sanzo, Elisa Luño, Teresa Giménez, Montserrat Arnan, Helena Pomares, Raquel De Paz, Beatriz Arrizabalaga, Andrés Jerez, Ana B Martínez, Judith Sánchez-Castro, Juan D Rodríguez-Gambarte, José M Raya, Eduardo Ríos, María Rodríguez-Rivera, Blanca Espinet, Lourdes Florensa

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Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease by Daehong Kim, Giljun Park, Jani Huuhtanen, Sofie Lundgren, Rajiv K. Khajuria, Ana M. Hurtado, Cecilia Muñoz-Calleja, Laura Cardeñoso, Valle Gómez-García de Soria, Tzu Hua Chen-Liang, Samuli Eldfors, Pekka Ellonen, Sari Hannula, Matti Kankainen, Oscar Bruck, Anna Kreutzman, Urpu Salmenniemi, Tapio Lönnberg, Andrés Jerez, Maija Itälä-Remes, Mikko Myllymäki, Mikko A. I. Keränen, Satu Mustjoki

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Machine Learning Improves Risk Stratification in Myelodysplastic Neoplasms: An Analysis of the Spanish Group of Myelodysplastic Syndromes by Adrian Mosquera Orgueira, Manuel Mateo Perez Encinas, Nicolas A Diaz Varela, Elvira Mora, Marina Díaz-Beyá, María Julia Montoro, Helena Pomares, Fernando Ramos, Mar Tormo, Andres Jerez, Josep F Nomdedeu, Carlos De Miguel Sanchez, Arenillas Leonor, Paula Cárcel, Maria Teresa Cedena Romero, Blanca Xicoy, Eugenia Rivero, Rafael Andres del Orbe Barreto, Maria Diez-Campelo, Luis E. Benlloch, Davide Crucitti, David Valcárcel

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P703: THE AIPSS-MDS MACHINE LEARNING MODEL PREDICTS OVERALL SURVIVAL AND LEUKEMIC TRANSFORMATION IN CMML: AN ANALYSIS OF THE SPANISH REGISTRY OF MDS by Adrian Mosquera-Orgueira, Manuel Mateo Perez Encinas, Nicolas Diaz Varela, Yu-Hung Wang, Elvira Mora, Marina Diaz-Beya, Maria Julia Montoro, Helena Pomares Marin, Fernando Ramos Ortega, Mar Tormo, Andres Jerez, Josep Nomdedeu, Carlos de Migue Sanchez, Leonor Arenillas, Paula Carcel, Maria Teresa Cedena Romero, Blanca Xicoy Cirici, Eugenia Rivero Arango, Rafael Andrés Del Orbe Barreto, Luis Benlloch, Chien-Chin Lin, Hwei-Fang Tien, María Díez Campelo, Davide Crucitti, David Valcárcel

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Accuracy and prognostic impact of FDG PET/CT and biopsy in bone marrow assessment of follicular lymphoma at diagnosis: A Nation‐Wide cohort study by Isabel Ródenas‐Quiñonero, Tzu Chen‐Liang, Taida Martín‐Santos, Antonio Salar, Marta Fernández‐González, Carolina Celades, José‐Tomás Navarro, Ana Belén Martínez‐Garcia, Rafael Andreu, Aitana Balaguer, Alejandro Martin García‐Sancho, Mónica Baile, Javier López‐Jiménez, Juan Marquet‐Palomanes, Ana Isabel Teruel, María José Terol, Carmen Benet, Laura Frutos, José Luis Navarro, Jon Uña, Marina Suarez, Montserrat Cortes, José Contreras, Cristina Ruiz, Pilar Tamayo, Jorge Mucientes, Pablo Sopena‐Novales, Laura Reguilón‐Gallego, José Javier Sánchez‐Blanco, Elena Pérez‐Ceballos, Andrés Jerez, Francisco José Ortuño

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Do GWAS-Identified Risk Variants for Chronic Lymphocytic Leukemia Influence Overall Patient Survival and Disease Progression? by Antonio José Cabrera-Serrano, José Manuel Sánchez-Maldonado, Rob ter Horst, Angelica Macauda, Paloma García-Martín, Yolanda Benavente, Stefano Landi, Alyssa Clay-Gilmour, Yasmeen Niazi, Blanca Espinet, Juan José Rodríguez-Sevilla, Eva María Pérez, Rossana Maffei, Gonzalo Blanco, Matteo Giaccherini, James R. Cerhan, Roberto Marasca, Miguel Ángel López-Nevot, Tzu Chen-Liang, Hauke Thomsen, Irene Gámez, Daniele Campa, Víctor Moreno, Silvia de Sanjosé, Rafael Marcos-Gragera, María García-Álvarez, Trinidad Dierssen-Sotos, Andrés Jerez, Aleksandra Butrym, Aaron D. Norman, Mario Luppi, Susan L. Slager, Kari Hemminki, Yang Li, Sonja I. Berndt, Delphine Casabonne, Miguel Alcoceba, Anna Puiggros, Mihai G. Netea, Asta Försti, Federico Canzian, Juan Sainz

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Validation and functional characterization of GWAS-identified variants for chronic lymphocytic leukemia: a CRuCIAL study by Paloma García-Martín, Ana Moñiz Díez, José Manuel Sánchez Maldonado, Antonio José Cabrera Serrano, Rob ter Horst, Yolanda Benavente, Stefano Landi, Angelica Macauda, Alyssa Clay-Gilmour, Francisca Hernández-Mohedo, Yasmeen Niazi, Pedro González-Sierra, Blanca Espinet, Juan José Rodríguez-Sevilla, Rossana Maffei, Gonzalo Blanco, Matteo Giaccherini, Anna Puiggros, James Cerhan, Roberto Marasca, Marisa Cañadas-Garre, Miguel Ángel López-Nevot, Tzu Chen-Liang, Hauke Thomsen, Irene Gámez, Víctor Moreno, Rafael Marcos-Gragera, María García-Álvarez, Javier Llorca, Andrés Jerez, Sonja Berndt, Aleksandra Butrym, Aaron D. Norman, Delphine Casabonne, Mario Luppi, Susan L. Slager, Kari Hemminki, Yang Li, Miguel Alcoceba, Daniele Campa, Federico Canzian, Silvia de Sanjosé, Asta Försti, Mihai G. Netea, Manuel Jurado, Juan Sainz

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Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization by Esther Clavero, José Manuel Sanchez-Maldonado, Angelica Macauda, Rob Ter Horst, Belém Sampaio-Marques, Artur Jurczyszyn, Alyssa Clay-Gilmour, Angelika Stein, Michelle A. T. Hildebrandt, Niels Weinhold, Gabriele Buda, Ramón García-Sanz, Waldemar Tomczak, Ulla Vogel, Andrés Jerez, Daria Zawirska, Marzena Wątek, Jonathan N. Hofmann, Stefano Landi, John J. Spinelli, Aleksandra Butrym, Abhishek Kumar, Joaquín Martínez-López, Sara Galimberti, María Eugenia Sarasquete, Edyta Subocz, Elzbieta Iskierka-Jażdżewska, Graham G. Giles, Malwina Rybicka-Ramos, Marcin Kruszewski, Niels Abildgaard, Francisco García Verdejo, Pedro Sánchez Rovira, Miguel Inacio da Silva Filho, Katalin Kadar, Małgorzata Razny, Wendy Cozen, Matteo Pelosini, Manuel Jurado, Parveen Bhatti, Marek Dudzinski, Agnieszka Druzd-Sitek, Enrico Orciuolo, Yang Li, Aaron D. Norman, Jan Maciej Zaucha, Rui Manuel Reis, Miroslaw Markiewicz, Juan José Rodríguez Sevilla, Vibeke Andersen, Krzysztof Jamroziak, Kari Hemminki, Sonja I. Berndt, Vicent Rajkumar, Grzegorz Mazur, Shaji K. Kumar, Paula Ludovico, Arnon Nagler, Stephen J. Chanock, Charles Dumontet, Mitchell J. Machiela, Judit Varkonyi, Nicola J. Camp, Elad Ziv, Annette Juul Vangsted, Elizabeth E. Brown, Daniele Campa, Celine M. Vachon, Mihai G. Netea, Federico Canzian, Asta Försti, Juan Sainz

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