Immune Escape Mechanisms in Non Small Cell Lung Cancer by Andrea Anichini, Valentina E. Perotti, Francesco Sgambelluri, Roberta Mortarini

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A Bispecific Antibody to Link a TRAIL-Based Antitumor Approach to Immunotherapy by Alessandro Satta, Giulia Grazia, Francesco Caroli, Barbara Frigerio, Massimo Di Nicola, Francesco Raspagliesi, Delia Mezzanzanica, Nadia Zaffaroni, Alessandro Massimo Gianni, Andrea Anichini, Mariangela Figini

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Improved Prognostic Prediction in Never-Smoker Lung Cancer Patients by Integration of a Systemic Inflammation Marker with Tumor Immune Contexture Analysis by Massimo Milione, Mattia Boeri, Anna Cantarutti, Giovanni Centonze, Adele Busico, Paola Suatoni, Giovanna Garzone, Laura Cattaneo, Elena Tamborini, Federica Perrone, Alessandro Mangogna, Giovanni Corrao, Giancarlo Pruneri, Gabriella Sozzi, Andrea Anichini, Ugo Pastorino

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Growth-Inhibitory and Antiangiogenic Activity of the MEK Inhibitor PD0325901 in Malignant Melanoma with or without BRAF Mutations by Ludovica Ciuffreda, Donatella Del Bufalo, Marianna Desideri, Cristina Di Sanza, Antonella Stoppacciaro, Maria Rosaria Ricciardi, Sabina Chiaretti, Simona Tavolaro, Barbara Benassi, Alfonso Bellacosa, Robin Foà, Agostino Tafuri, Francesco Cognetti, Andrea Anichini, Gabriella Zupi, Michele Milella

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Case Report: Exceptional Response to Avelumab After Failure of Electrochemotherapy in a Patient With Rapidly Progressive, PD-L1-Negative Merkel Cell Carcinoma by Martina Torchio, Laura Cattaneo, Massimo Milione, Natalie Prinzi, Francesca Corti, Marco Ungari, Andrea Anichini, Roberta Mortarini, Antonio Occhini, Giulia Bertino, Andrea Maurichi, Jorgelina Coppa, Maria Di Bartolomeo, Filippo Guglielmo de Braud, Filippo Guglielmo de Braud, Sara Pusceddu

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Myeloid and T-Cell Microenvironment Immune Features Identify Two Prognostic Sub-Groups in High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms by Giovanni Centonze, Vincenzo Lagano, Giovanna Sabella, Alessandro Mangogna, Giovanna Garzone, Martina Filugelli, Beatrice Belmonte, Laura Cattaneo, Valentina Crisafulli, Alessio Pellegrinelli, Michele Simbolo, Aldo Scarpa, Paola Spaggiari, Tatiana Brambilla, Sara Pusceddu, Natalie Prinzi, Andrea Anichini, Claudio Tripodo, Massimo Milione

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Gut Microbiota, Metabolome, and Body Composition Signatures of Response to Therapy in Patients with Advanced Melanoma by Giulia Vandoni, Federica D'Amico, Marco Fabbrini, Luigi Mariani, Sabina Sieri, Amanda Casirati, Lorenza Di Guardo, Michele Del Vecchio, Andrea Anichini, Roberta Mortarini, Francesco Sgambelluri, Giuseppe Celano, Nadia Serale, Maria De Angelis, Patrizia Brigidi, Cecilia Gavazzi, Silvia Turroni

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Microenvironment and tumor inflammatory features improve prognostic prediction in gastro‐entero‐pancreatic neuroendocrine neoplasms by Massimo Milione, Rosalba Miceli, Francesco Barretta, Alessio Pellegrinelli, Paola Spaggiari, Giovanna Tagliabue, Giovanni Centonze, Cinzia Paolino, Alessandro Mangogna, Ketevani Kankava, Sara Pusceddu, Luca Giacomelli, Ambra Corti, Christian Cotsoglou, Vincenzo Mazzaferro, Gabriella Sozzi, Filippo deBraud, Giancarlo Pruneri, Andrea Anichini

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A novel microRNA signature for the detection of melanoma by liquid biopsy by Claudia Sabato, Teresa Maria Rosaria Noviello, Alessia Covre, Sandra Coral, Francesca Pia Caruso, Zein Mersini Besharat, Elena Splendiani, Laura Masuelli, Cecilia Battistelli, Alessandra Vacca, Giuseppina Catanzaro, Agnese Po, Andrea Anichini, Michele Maio, Michele Ceccarelli, Anna Maria Di Giacomo, Elisabetta Ferretti

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Semaphorin 5A drives melanoma progression: role of Bcl-2, miR-204 and c-Myb by Simona D’Aguanno, Elisabetta Valentini, Maria Grazia Tupone, Marianna Desideri, Marta Di Martile, Manuela Spagnuolo, Simonetta Buglioni, Cristiana Ercolani, Italia Falcone, Marco De Dominici, Michele Milella, Maria Giulia Rizzo, Bruno Calabretta, Carlo Cota, Andrea Anichini, Daniela Trisciuoglio, Donatella Del Bufalo

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Cancer Associated Fibroblasts and Senescent Thyroid Cells in the Invasive Front of Thyroid Carcinoma by Emanuela Minna, Silvia Brich, Katia Todoerti, Silvana Pilotti, Paola Collini, Elisa Bonaldi, Paola Romeo, Loris De Cecco, Matteo Dugo, Federica Perrone, Adele Busico, Andrea Vingiani, Ilaria Bersani, Andrea Anichini, Roberta Mortarini, Antonino Neri, Giancarlo Pruneri, Angela Greco, Maria Grazia Borrello

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Epigenetic remodeling to improve the efficacy of immunotherapy in human glioblastoma: pre-clinical evidence for development of new immunotherapy approaches by Maria Fortunata Lofiego, Francesca Piazzini, Francesca Pia Caruso, Francesco Marzani, Laura Solmonese, Emma Bello, Fabrizio Celesti, Maria Claudia Costa, Teresa Noviello, Roberta Mortarini, Andrea Anichini, Michele Ceccarelli, Sandra Coral, Anna Maria Di Giacomo, Michele Maio, Alessia Covre, The EPigenetic Immune-oncology Consortium Airc (EPICA) investigators

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Guadecitabine plus ipilimumab in unresectable melanoma: five-year follow-up and integrated multi-omic analysis in the phase 1b NIBIT-M4 trial by Teresa Maria Rosaria Noviello, Anna Maria Di Giacomo, Francesca Pia Caruso, Alessia Covre, Roberta Mortarini, Giovanni Scala, Maria Claudia Costa, Sandra Coral, Wolf H. Fridman, Catherine Sautès-Fridman, Silvia Brich, Giancarlo Pruneri, Elena Simonetti, Maria Fortunata Lofiego, Rossella Tufano, Davide Bedognetti, Andrea Anichini, Michele Maio, Michele Ceccarelli

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A microRNA Prognostic Signature in Patients with Diffuse Intrinsic Pontine Gliomas through Non-Invasive Liquid Biopsy by Maria F. Iannó, Veronica Biassoni, Elisabetta Schiavello, Andrea Carenzo, Luna Boschetti, Lorenza Gandola, Barbara Diletto, Edoardo Marchesi, Claudia Vegetti, Alessandra Molla, Christof M. Kramm, Dannis G. van Vuurden, Patrizia Gasparini, Francesca Gianno, Felice Giangaspero, Piergiorgio Modena, Brigitte Bison, Andrea Anichini, Sabina Vennarini, Emanuele Pignoli, Maura Massimino, Loris De Cecco

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IL-15, TIM-3 and NK cells subsets predict responsiveness to anti-CTLA-4 treatment in melanoma patients by Rossana Tallerico, Costanza M. Cristiani, Elina Staaf, Cinzia Garofalo, Rosa Sottile, Mariaelena Capone, Yago Pico de Coaña, Gabriele Madonna, Eleonora Palella, Maria Wolodarski, Valentina Carannante, Domenico Mallardo, Ester Simeone, Antonio M. Grimaldi, Sofia Johansson, Paolo Frumento, Elio Gulletta, Andrea Anichini, Francesco Colucci, Gennaro Ciliberto, Rolf Kiessling, Klas Kärre, Paolo A. Ascierto, Ennio Carbone

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Landscape of immune-related signatures induced by targeting of different epigenetic regulators in melanoma: implications for immunotherapy by Andrea Anichini, Alessandra Molla, Gabriella Nicolini, Valentina Eleonora Perotti, Francesco Sgambelluri, Alessia Covre, Carolina Fazio, Maria Fortunata Lofiego, Anna Maria Di Giacomo, Sandra Coral, Antonella Manca, Maria Cristina Sini, Marina Pisano, Teresa Noviello, Francesca Caruso, Silvia Brich, Giancarlo Pruneri, Andrea Maurichi, Mario Santinami, Michele Ceccarelli, Giuseppe Palmieri, Michele Maio, Roberta Mortarini, On behalf of the EPigenetic Immune-oncology Consortium AIRC (EPICA) investigators

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Antibody dependent cellular cytotoxicity-inducing anti-EGFR antibodies as effective therapeutic option for cutaneous melanoma resistant to BRAF inhibitors by Elena Muraro, Barbara Montico, Benedict Lum, Francesca Colizzi, Giorgio Giurato, Giorgio Giurato, Annamaria Salvati, Annamaria Salvati, Annamaria Salvati, Roberto Guerrieri, Aurora Rizzo, Elisa Comaro, Vincenzo Canzonieri, Vincenzo Canzonieri, Andrea Anichini, Michele Del Vecchio, Roberta Mortarini, Massimo Milione, Alessandro Weisz, Alessandro Weisz, Alessandro Weisz, Maria Antonietta Pizzichetta, Maria Antonietta Pizzichetta, Fiona Simpson, Riccardo Dolcetti, Riccardo Dolcetti, Riccardo Dolcetti, Riccardo Dolcetti, Elisabetta Fratta, Luca Sigalotti

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PEOPLE (NTC03447678), a phase II trial to test pembrolizumab as first-line treatment in patients with advanced NSCLC with PD-L1 by Filippo de Braud, Valter Torri, Giuseppe Lo Russo, Claudia Proto, Roberto Ferrara, Monica Ganzinelli, Marina Chiara Garassino, Giuseppe Viscardi, Giorgio Trinchieri, Mario Occhipinti, Rita Leporati, Marta Brambilla, Luca Agnelli, Silvia Brich, Francesco Sgambelluri, Roberta Mortarini, Andrea Anichini, Leonardo Provenzano, Daniele Lorenzini, Arsela Prelaj, James Dolezal, Teresa Beninato, Tiziana Triulzi, Alessandra Fabbri, Laura Mazzeo, Andrea Spagnoletti, Vanja Miskovic, Alessandra Laura Giulia Pedrocchi, Francesco Trovo', Sara Manglaviti, Claudia Giani, Paolo Ambrosini, Andrea Franza, John McCulloch, Tommaso Torelli, Giancarlo Pruneri

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