Editorial: Brain cancer pathogenesis and data integration by Andrea Comba, Xinzhong Li, Barbara Breznik

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Uncovering Spatiotemporal Heterogeneity of High-Grade Gliomas: From Disease Biology to Therapeutic Implications by Andrea Comba, Andrea Comba, Andrea Comba, Syed M. Faisal, Syed M. Faisal, Syed M. Faisal, Maria Luisa Varela, Maria Luisa Varela, Maria Luisa Varela, Todd Hollon, Wajd N. Al-Holou, Yoshie Umemura, Felipe J. Nunez, Sebastien Motsch, Maria G. Castro, Maria G. Castro, Maria G. Castro, Pedro R. Lowenstein, Pedro R. Lowenstein, Pedro R. Lowenstein

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The complex interactions between the cellular and non-cellular components of the brain tumor microenvironmental landscape and their therapeutic implications by Syed M. Faisal, Syed M. Faisal, Syed M. Faisal, Andrea Comba, Andrea Comba, Andrea Comba, Maria L. Varela, Maria L. Varela, Maria L. Varela, Anna E. Argento, Emily Brumley, Emily Brumley, Emily Brumley, Clifford Abel, Clifford Abel, Clifford Abel, Maria G. Castro, Maria G. Castro, Maria G. Castro, Pedro R. Lowenstein, Pedro R. Lowenstein, Pedro R. Lowenstein, Pedro R. Lowenstein

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3131 ONCOSTREAMS: NOVEL DYNAMICS PATHOLOGICAL MULTICELLULAR STRUCTURES INVOLVED IN GLIOBLATOMA GROWTH AND INVASION by Andrea Comba, Patrick Dunn, Anna E Argento, Padma Kadiyala, Sebastien Motsch, Phillip Kish, Alon Kahana, Daniel Zamler, Karin Muraszko, Maria G Castro, Pedro R Lowenstein

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Generation of 3D ex vivo mouse- and patient-derived glioma explant slice model for integration of confocal time-lapse imaging and spatial analysis by Andrea Comba, Maria Luisa Varela, Syed M. Faisal, Clifford C. Abel, II, Anna E. Argento, Wajd N. Al-Holou, Todd C. Hollon, Jacqueline D. Perelman, Patrick J. Dunn, Sebastien Motsch, Maria G. Castro, Pedro R. Lowenstein

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Genetic Alterations in Gliomas Remodel the Tumor Immune Microenvironment and Impact Immune-Mediated Therapies by Maria B. Garcia-Fabiani, Maria B. Garcia-Fabiani, Santiago Haase, Santiago Haase, Andrea Comba, Andrea Comba, Stephen Carney, Stephen Carney, Brandon McClellan, Brandon McClellan, Kaushik Banerjee, Kaushik Banerjee, Mahmoud S. Alghamri, Mahmoud S. Alghamri, Faisal Syed, Faisal Syed, Padma Kadiyala, Padma Kadiyala, Felipe J. Nunez, Marianela Candolfi, Antonela Asad, Nazareno Gonzalez, Marisa E. Aikins, Marisa E. Aikins, Anna Schwendeman, Anna Schwendeman, James J. Moon, James J. Moon, James J. Moon, Pedro R. Lowenstein, Pedro R. Lowenstein, Maria G. Castro, Maria G. Castro

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Development of immunotherapy for high-grade gliomas: Overcoming the immunosuppressive tumor microenvironment by Andrea Franson, Brandon L. McClellan, Brandon L. McClellan, Brandon L. McClellan, Maria Luisa Varela, Andrea Comba, Mohammad Faisal Syed, Kaushik Banerjee, Ziwen Zhu, Nazareno Gonzalez, Marianela Candolfi, Pedro Lowenstein, Pedro Lowenstein, Pedro Lowenstein, Pedro Lowenstein, Maria Graciela Castro, Maria Graciela Castro, Maria Graciela Castro

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The transcription factor GLI1 mediates TGFβ1 driven EMT in hepatocellular carcinoma via a SNAI1-dependent mechanism. by Xin Zheng, Natalia B Rumie Vittar, Xiaohong Gai, Maite G Fernandez-Barrena, Catherine D Moser, Chunling Hu, Luciana L Almada, Angela L McCleary-Wheeler, Sherine F Elsawa, Anne M Vrabel, Abdirashid M Shire, Andrea Comba, Snorri S Thorgeirsson, Youngsoo Kim, Qingguang Liu, Martin E Fernandez-Zapico, Lewis R Roberts

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Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression by Andrea Comba, Syed M. Faisal, Patrick J. Dunn, Anna E. Argento, Todd C. Hollon, Wajd N. Al-Holou, Maria Luisa Varela, Daniel B. Zamler, Gunnar L. Quass, Pierre F. Apostolides, Clifford Abel, Christine E. Brown, Phillip E. Kish, Alon Kahana, Celina G. Kleer, Sebastien Motsch, Maria G. Castro, Pedro R. Lowenstein

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H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models by Santiago Haase, Kaushik Banerjee, Anzar A. Mujeeb, Carson S. Hartlage, Fernando M. Núñez, Felipe J. Núñez, Mahmoud S. Alghamri, Padma Kadiyala, Stephen Carney, Marcus N. Barissi, Ayman W. Taher, Emily K. Brumley, Sarah Thompson, Justin T. Dreyer, Caitlin T. Alindogan, Maria B. Garcia-Fabiani, Andrea Comba, Sriram Venneti, Visweswaran Ravikumar, Carl Koschmann, Ángel M. Carcaboso, Maria Vinci, Arvind Rao, Jennifer S. Yu, Pedro R. Lowenstein, Maria G. Castro

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