Huntingtin Ubiquitination Mechanisms and Novel Possible Therapies to Decrease the Toxic Effects of Mutated Huntingtin by Annarita Fiorillo, Veronica Morea, Gianni Colotti, Andrea Ilari

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Targeting Trypanothione Reductase, a Key Enzyme in the Redox Trypanosomatid Metabolism, to Develop New Drugs against Leishmaniasis and Trypanosomiases by Theo Battista, Gianni Colotti, Andrea Ilari, Annarita Fiorillo

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The crystal structures of the tryparedoxin-tryparedoxin peroxidase couple unveil the structural determinants of Leishmania detoxification pathway. by Annarita Fiorillo, Gianni Colotti, Alberto Boffi, Paola Baiocco, Andrea Ilari

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Roles of Sorcin in Drug Resistance in Cancer: One Protein, Many Mechanisms, for a Novel Potential Anticancer Drug Target by Theo Battista, Annarita Fiorillo, Valerio Chiarini, Ilaria Genovese, Andrea Ilari, Gianni Colotti

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Sorcin, a Calcium Binding Protein Involved in the Multidrug Resistance Mechanisms in Cancer Cells by Gianni Colotti, Elena Poser, Annarita Fiorillo, Ilaria Genovese, Valerio Chiarini, Andrea Ilari

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Sorcin links calcium signaling to vesicle trafficking, regulates Polo-like kinase 1 and is necessary for mitosis. by Vasiliki S Lalioti, Andrea Ilari, David J O'Connell, Elena Poser, Ignacio V Sandoval, Gianni Colotti

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The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme. by Annarita Fiorillo, Maria Petrosino, Andrea Ilari, Alessandra Pasquo, Alessandra Cipollone, Maristella Maggi, Roberta Chiaraluce, Valerio Consalvi

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The crystal structure of Giardia duodenalis 14-3-3 in the apo form: when protein post-translational modifications make the difference. by Annarita Fiorillo, Daniele di Marino, Lucia Bertuccini, Allegra Via, Edoardo Pozio, Serena Camerini, Andrea Ilari, Marco Lalle

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Investigation of the Entry Pathway and Molecular Nature of σ1 Receptor Ligands by Gianmarco Pascarella, Lorenzo Antonelli, Daniele Narzi, Theo Battista, Annarita Fiorillo, Gianni Colotti, Leonardo Guidoni, Veronica Morea, Andrea Ilari

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Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design by Annarita Fiorillo, Annarita Fiorillo, Gianni Colotti, Gianni Colotti, Cécile Exertier, Anastasia Liuzzi, Francesca Seghetti, Alessandra Salerno, Jessica Caciolla, Andrea Ilari

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Generation of induced pluripotent stem cell line, CSSi004-A (2962), from a patient diagnosed with Huntington's disease at the presymptomatic stage by Eris Bidollari, Giovannina Rotundo, Daniela Ferrari, Ornella Candido, Laura Bernardini, Federica Consoli, Alessandro De Luca, Iolanda Santimone, Giuseppe Lamorte, Andrea Ilari, Ferdinando Squitieri, Angelo Luigi Vescovi, Jessica Rosati

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Inhibition of <i>Leishmania infantum</i> Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site by Valentina Noemi Madia, Davide Ialongo, Elisa Patacchini, Cécile Exertier, Lorenzo Antonelli, Gianni Colotti, Antonella Messore, Valeria Tudino, Francesco Saccoliti, Luigi Scipione, Andrea Ilari, Roberta Costi, Roberto Di Santo

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Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives by Francesco Saccoliti, Gabriella Angiulli, Giovanni Pupo, Luca Pescatori, Valentina Noemi Madia, Antonella Messore, Gianni Colotti, Annarita Fiorillo, Luigi Scipione, Marina Gramiccia, Trentina Di Muccio, Roberto Di Santo, Roberta Costi, Andrea Ilari

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Known Drugs Identified by Structure-Based Virtual Screening Are Able to Bind Sigma-1 Receptor and Increase Growth of Huntington Disease Patient-Derived Cells by Theo Battista, Gianmarco Pascarella, David Sasah Staid, Gianni Colotti, Jessica Rosati, Annarita Fiorillo, Alessia Casamassa, Angelo Luigi Vescovi, Barbara Giabbai, Marta Stefania Semrau, Sergio Fanelli, Paola Storici, Ferdinando Squitieri, Veronica Morea, Andrea Ilari

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