Editorial: Targeting Thyroid Hormone-Dependent Pathways in Proliferative and Degenerative Disorders by Andrea Perra, Michelina Plateroti

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Emerging Role of the Pentose Phosphate Pathway in Hepatocellular Carcinoma by Marta Anna Kowalik, Amedeo Columbano, Andrea Perra

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Thyroid Hormones, Thyromimetics and Their Metabolites in the Treatment of Liver Disease by Marta A. Kowalik, Amedeo Columbano, Andrea Perra

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Animal Models: A Useful Tool to Unveil Metabolic Changes in Hepatocellular Carcinoma by Marina Serra, Amedeo Columbano, Andrea Perra, Marta Anna Kowalik

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HPV related p16INK4A and HSV in benign and potentially malignant oral mucosa pathologies by Irena Duś-Ilnicka, Agnieszka Hałoń, Andrea Perra, Małgorzata Radwan-Oczko

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Sex difference in liver diseases: How preclinical models help to dissect the sex-related mechanisms sustaining NAFLD and hepatocellular carcinoma by Alfredo Smiriglia, Nicla Lorito, Marina Serra, Andrea Perra, Andrea Morandi, Marta Anna Kowalik

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Distinct Mechanisms Are Responsible for Nrf2-Keap1 Pathway Activation at Different Stages of Rat Hepatocarcinogenesis by Claudia Orrù, Andrea Perra, Marta Anna Kowalik, Sabrina Rizzolio, Elisabetta Puliga, Lavinia Cabras, Silvia Giordano, Amedeo Columbano

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Non-Invasive Detection of a De Novo Frameshift Variant of <i>STAG2</i> in a Female Fetus: Escape Genes Influence the Manifestation of X-Linked Diseases in Females by Aldesia Provenzano, Andrea La Barbera, Francesco Lai, Andrea Perra, Antonio Farina, Ettore Cariati, Orsetta Zuffardi, Sabrina Giglio

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TG68, a Novel Thyroid Hormone Receptor-β Agonist for the Treatment of NAFLD by Andrea Caddeo, Marta Anna Kowalik, Marina Serra, Massimiliano Runfola, Andrea Bacci, Simona Rapposelli, Amedeo Columbano, Andrea Perra

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Decision trees for early prediction of inadequate immune response to coronavirus infections: a pilot study on COVID-19 by Fabio Pisano, Barbara Cannas, Alessandra Fanni, Manuela Pasella, Beatrice Canetto, Sabrina Rita Giglio, Sabrina Rita Giglio, Sabrina Rita Giglio, Sabrina Rita Giglio, Stefano Mocci, Stefano Mocci, Luchino Chessa, Luchino Chessa, Luchino Chessa, Andrea Perra, Andrea Perra, Roberto Littera, Roberto Littera

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Potential use of TG68 - A novel thyromimetic - for the treatment of non-alcoholic fatty liver (NAFLD)-associated hepatocarcinogenesis by Andrea Caddeo, Marina Serra, Francesca Sedda, Andrea Bacci, Clementina Manera, Simona Rapposelli, Amedeo Columbano, Andrea Perra, Marta Anna Kowalik

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A Protective HLA Extended Haplotype Outweighs the Major COVID-19 Risk Factor Inherited From Neanderthals in the Sardinian Population by Stefano Mocci, Roberto Littera, Roberto Littera, Stefania Tranquilli, Aldesia Provenzano, Alessia Mascia, Federica Cannas, Sara Lai, Erika Giuressi, Luchino Chessa, Luchino Chessa, Luchino Chessa, Goffredo Angioni, Marcello Campagna, Davide Firinu, Maria Del Zompo, Giorgio La Nasa, Andrea Perra, Andrea Perra, Sabrina Giglio, Sabrina Giglio, Sabrina Giglio

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COVID-19 Vaccine Hesitancy among Italian Healthcare Workers: Latent Profiles and Their Relationships to Predictors and Outcome by Igor Portoghese, Melinda Siddi, Luchino Chessa, Giulia Costanzo, Vanessa Garcia-Larsen, Andrea Perra, Roberto Littera, Giada Sambugaro, Stefano Del Giacco, Marcello Campagna, Davide Firinu

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mRNA-miRNA networks identify metabolic pathways associated to the anti-tumorigenic effect of thyroid hormone on preneoplastic nodules and hepatocellular carcinoma by Marina Serra, Rajesh Pal, Elisabetta Puliga, Elisabetta Puliga, Pia Sulas, Lavinia Cabras, Roberto Cusano, Silvia Giordano, Silvia Giordano, Andrea Perra, Amedeo Columbano, Marta Anna Kowalik

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Multi-Organ Morphological Findings in a Humanized Murine Model of Sickle Cell Trait by Marcello Trucas, Sabrina Burattini, Susanna Porcu, Michela Simbula, Maria Serafina Ristaldi, Marta Anna Kowalik, Maria Pina Serra, Pietro Gobbi, Michela Battistelli, Andrea Perra, Marina Quartu

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Nrf2 Mutation/Activation Is Dispensable for the Development of Chemically Induced Mouse HCCSummary by Sandra Mattu, Patrizia Zavattari, Marta Anna Kowalik, Marina Serra, Pia Sulas, Rajesh Pal, Elisabetta Puliga, Salvatore Sutti, Beatrice Foglia, Maurizio Parola, Emanuele Albano, Silvia Giordano, Andrea Perra, Amedeo Columbano

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Entropy of human leukocyte antigen and killer-cell immunoglobulin-like receptor systems in immune-mediated disorders: A pilot study on multiple sclerosis. by Maurizio Melis, Roberto Littera, Eleonora Cocco, Jessica Frau, Sara Lai, Elena Congeddu, Paola Ragatzu, Maria Serra, Valentina Loi, Roberta Maddi, Roberta Pitzalis, Sandro Orrù, Luchino Chessa, Andrea Perra, Carlo Carcassi

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A review of the main genetic factors influencing the course of COVID-19 in Sardinia: the role of human leukocyte antigen-G by Stefano Mocci, Stefano Mocci, Roberto Littera, Roberto Littera, Luchino Chessa, Luchino Chessa, Luchino Chessa, Marcello Campagna, Maurizio Melis, Carla Maria Ottelio, Ignazio S. Piras, Sara Lai, Davide Firinu, Stefania Tranquilli, Alessia Mascia, Monica Vacca, Daniele Schirru, Luigi Isaia Lecca, Stefania Rassu, Federica Cannas, Celeste Sanna, Mauro Giovanni Carta, Francesca Sedda, Erika Giuressi, Selene Cipri, Michela Miglianti, Andrea Perra, Andrea Perra, Sabrina Giglio, Sabrina Giglio, Sabrina Giglio

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Neutralizing Antibodies Responses against SARS-CoV-2 in a Sardinian Cohort Group Up to 9 Months after BNT162b2 Vaccination by Giuseppina Sanna, Alessandra Marongiu, Davide Firinu, Cristina Piras, Gianluigi Franci, Massimiliano Galdiero, Giuseppe Pala, Vanessa Palmas, Fabrizio Angius, Roberto Littera, Andrea Perra, Germano Orrù, Marcello Campagna, Giulia Costanzo, Federico Meloni, Ferdinando Coghe, Luchino Chessa, Aldo Manzin

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Evaluation of Antibody Response to Heterologous Prime–Boost Vaccination with ChAdOx1 nCoV-19 and BNT162b2: An Observational Study by Davide Firinu, Andrea Perra, Marcello Campagna, Roberto Littera, Federico Meloni, Francesca Sedda, Maria Conti, Giulia Costanzo, Monica Erbi, Gianmario Usai, Carlotta Locci, Mauro Giovanni Carta, Riccardo Cappai, Germano Orrù, Stefano Del Giacco, Ferdinando Coghe, Luchino Chessa

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