The Quest for Improving Treatment of Cancer of Unknown Primary (CUP) Through Molecularly-Driven Treatments: A Systematic Review by Roberta Lombardo, Roberta Lombardo, Federica Tosi, Federica Tosi, Annunziata Nocerino, Katia Bencardino, Valentina Gambi, Riccardo Ricotta, Francesco Spina, Salvatore Siena, Salvatore Siena, Andrea Sartore-Bianchi, Andrea Sartore-Bianchi

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Early‐onset colorectal cancer in young individuals by Gianluca Mauri, Andrea Sartore‐Bianchi, Antonio‐Giampiero Russo, Silvia Marsoni, Alberto Bardelli, Salvatore Siena

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Mechanisms of Immune Escape and Resistance to Checkpoint Inhibitor Therapies in Mismatch Repair Deficient Metastatic Colorectal Cancers by Vito Amodio, Gianluca Mauri, Nicole M. Reilly, Andrea Sartore-Bianchi, Salvatore Siena, Alberto Bardelli, Giovanni Germano

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Corrigendum: Case report: MAP2K1 K57N mutation is associated with primary resistance to anti-EGFR monoclonal antibodies in metastatic colorectal cancer by Gianluca Mauri, Gianluca Mauri, Gianluca Mauri, Giorgio Patelli, Giorgio Patelli, Viviana Gori, Viviana Gori, Calogero Lauricella, Benedetta Mussolin, Alessio Amatu, Katia Bencardino, Federica Tosi, Erica Bonazzina, Emanuela Bonoldi, Alberto Bardelli, Alberto Bardelli, Salvatore Siena, Salvatore Siena, Andrea Sartore-Bianchi, Andrea Sartore-Bianchi

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Case Report: MAP2K1 K57N mutation is associated with primary resistance to anti-EGFR monoclonal antibodies in metastatic colorectal cancer by Gianluca Mauri, Gianluca Mauri, Gianluca Mauri, Giorgio Patelli, Giorgio Patelli, Viviana Gori, Viviana Gori, Calogero Lauricella, Benedetta Mussolin, Alessio Amatu, Katia Bencardino, Federica Tosi, Erica Bonazzina, Emanuela Bonoldi, Alberto Bardelli, Alberto Bardelli, Salvatore Siena, Salvatore Siena, Andrea Sartore-Bianchi, Andrea Sartore-Bianchi

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CDK4/6 Inhibitors in Breast Cancer Treatment: Potential Interactions with Drug, Gene, and Pathophysiological Conditions by Rossana Roncato, Jacopo Angelini, Arianna Pani, Erika Cecchin, Andrea Sartore-Bianchi, Salvatore Siena, Elena De Mattia, Francesco Scaglione, Giuseppe Toffoli

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The Evolutionary Landscape of Treatment for <i>BRAF^V600E</i> Mutant Metastatic Colorectal Cancer by Gianluca Mauri, Erica Bonazzina, Alessio Amatu, Federica Tosi, Katia Bencardino, Viviana Gori, Daniela Massihnia, Tiziana Cipani, Francesco Spina, Silvia Ghezzi, Salvatore Siena, Andrea Sartore-Bianchi

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Liquid Biopsy for Small Cell Lung Cancer either De Novo or Transformed: Systematic Review of Different Applications and Meta-Analysis by Elio Gregory Pizzutilo, Martino Pedrani, Alessio Amatu, Lorenzo Ruggieri, Calogero Lauricella, Silvio Marco Veronese, Diego Signorelli, Giulio Cerea, Laura Giannetta, Salvatore Siena, Andrea Sartore-Bianchi

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Efficacy of Retreatment with Oxaliplatin-Based Regimens in Metastatic Colorectal Cancer Patients: The RETROX-CRC Retrospective Study by Alessio Amatu, Gianluca Mauri, Federica Tosi, Katia Bencardino, Erica Bonazzina, Viviana Gori, Lorenzo Ruggieri, Sabrina Arena, Alberto Bardelli, Silvia Marsoni, Salvatore Siena, Andrea Sartore-Bianchi

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Chemotherapy-induced myasthenic crisis in thymoma treated with primary chemotherapy with curative intent on mechanical ventilation: a case report and review of the literature by Giorgio Patelli, Katia Bencardino, Federica Tosi, Mariateresa Pugliano, Francesca Lanzani, Alessandro Innocenti, Alessandro Rinaldo, Gianluca Mauri, Giulio Cerea, Andrea Sartore-Bianchi, Massimo Torre, Elio Clemente Agostoni, Salvatore Siena

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Delta-Radiomics Predicts Response to First-Line Oxaliplatin-Based Chemotherapy in Colorectal Cancer Patients with Liver Metastases by Valentina Giannini, Laura Pusceddu, Arianna Defeudis, Giulia Nicoletti, Giovanni Cappello, Simone Mazzetti, Andrea Sartore-Bianchi, Salvatore Siena, Angelo Vanzulli, Francesco Rizzetto, Elisabetta Fenocchio, Luca Lazzari, Alberto Bardelli, Silvia Marsoni, Daniele Regge

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Phase II open-label study to assess efficacy and safety of lenalidomide in combination with cetuximab in KRAS-mutant metastatic colorectal cancer. by Salvatore Siena, Eric Van Cutsem, Mingyu Li, Ulf Jungnelius, Alfredo Romano, Robert Beck, Katia Bencardino, Maria Elena Elez, Hans Prenen, Mireia Sanchis, Andrea Sartore-Bianchi, Sabine Tejpar, Anita Gandhi, Tao Shi, Josep Tabernero

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Multimodal treatment with curative intent in a germline BRCA2 mutant metastatic ampullary adenocarcinoma: a case report by Gianluca Mauri, Viviana Gori, Giorgio Patelli, Laura Roazzi, Francesco Rizzetto, Luciano De Carlis, Anna Mariani, Ugo Cavallari, Elisabetta Prada, Tiziana Cipani, Maria Costanza Aquilano, Emanuela Bonoldi, Angelo Vanzulli, Salvatore Siena, Andrea Sartore-Bianchi

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High Circulating Methylated DNA Is a Negative Predictive and Prognostic Marker in Metastatic Colorectal Cancer Patients Treated With Regorafenib by Alessio Amatu, Marta Schirripa, Federica Tosi, Sara Lonardi, Katia Bencardino, Erica Bonazzina, Laura Palmeri, Damiano Alfio Patanè, Elio Gregory Pizzutilo, Benedetta Mussolin, Francesca Bergamo, Giulia Alberti, Giulia Alberti, Rossana Intini, Letizia Procaccio, Letizia Procaccio, Marco Arese, Marco Arese, Silvia Marsoni, Silvia Marsoni, Michele Nichelatti, Vittorina Zagonel, Salvatore Siena, Salvatore Siena, Alberto Bardelli, Alberto Bardelli, Fotios Loupakis, Federica Di Nicolantonio, Federica Di Nicolantonio, Andrea Sartore-Bianchi, Andrea Sartore-Bianchi, Ludovic Barault, Ludovic Barault

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Pneumatosis Intestinalis Induced by Anticancer Treatment: A Systematic Review by Gianluca Gazzaniga, Federica Villa, Federica Tosi, Elio Gregory Pizzutilo, Stefano Colla, Stefano D’Onghia, Giusy Di Sanza, Giulia Fornasier, Michele Gringeri, Maria Victoria Lucatelli, Giulia Mosini, Arianna Pani, Salvatore Siena, Francesco Scaglione, Andrea Sartore-Bianchi

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Reliance upon ancestral mutations is maintained in colorectal cancers that heterogeneously evolve during targeted therapies by Mariangela Russo, Simona Lamba, Annalisa Lorenzato, Alberto Sogari, Giorgio Corti, Giuseppe Rospo, Benedetta Mussolin, Monica Montone, Luca Lazzari, Sabrina Arena, Daniele Oddo, Michael Linnebacher, Andrea Sartore-Bianchi, Filippo Pietrantonio, Salvatore Siena, Federica Di Nicolantonio, Alberto Bardelli

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Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer by Beth O. Van Emburgh, Sabrina Arena, Giulia Siravegna, Luca Lazzari, Giovanni Crisafulli, Giorgio Corti, Benedetta Mussolin, Federica Baldi, Michela Buscarino, Alice Bartolini, Emanuele Valtorta, Joana Vidal, Beatriz Bellosillo, Giovanni Germano, Filippo Pietrantonio, Agostino Ponzetti, Joan Albanell, Salvatore Siena, Andrea Sartore-Bianchi, Federica Di Nicolantonio, Clara Montagut, Alberto Bardelli

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Pertuzumab and trastuzumab emtansine in patients with HER2-amplified metastatic colorectal cancer: the phase II HERACLES-B trial by Sara Lonardi, Valter Torri, Fortunato Ciardiello, Andrea Sartore-Bianchi, Salvatore Siena, Silvia Marsoni, Alberto Bardelli, Francesca Bergamo, Cosimo Martino, Elisabetta Fenocchio, Federica Tosi, Silvia Ghezzi, Francesco Leone, Vittorina Zagonel, Andrea Ardizzoni, Alessio Amatu, Katia Bencardino, Emanuele Valtorta, Elena Grassi, Emanuela Bonoldi, Anna Sapino, Angelo Vanzulli, Daniele Regge, Giovanni Cappello, Livio Trusolino

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Repotrectinib Overcomes F2004V Resistance Mutation in ROS1-Rearranged NSCLC: A Case Report by Elio Gregory Pizzutilo, MD, Alberto Giuseppe Agostara, MD, Laura Roazzi, MD, Rebecca Romanò, MD, Valentina Motta, PhD, Calogero Lauricella, PhD, Giovanna Marrapese, PhD, Giulio Cerea, MD, Diego Signorelli, MD, PhD, Silvio Marco Veronese, PhD, Laura Giuseppina Giannetta, MD, Andrea Sartore-Bianchi, MD, Salvatore Siena, MD

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Randomized phase II trial of avelumab alone or in combination with cetuximab for patients with previously treated, locally advanced, or metastatic squamous cell anal carcinoma: the... by Matteo Fassan, Fotios Loupakis, Sara Lonardi, Federica Morano, Mariaelena Casagrande, Filippo Pietrantonio, Gianluca Masi, Marco Messina, Andrea Sartore-Bianchi, Paola Del Bianco, Francesca Bergamo, Angela Buonadonna, Vittorina Zagonel, Massimiliano Spada, Monica Ronzoni, Salvatore Corallo, Michele Prisciandaro, Giovanni Luca Frassineti, Alessandra Anna Prete, Vincenzo Formica, Domenico Cristiano Corsi, Corrado Orciuolo, Maria Giulia Zampino, Mario Scartozzi, Stefania Mosconi, Margherita Ratti, Emiliano Tamburini, Valentina Vettore

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