Hormone Receptor Loss in Breast Cancer: Molecular Mechanisms, Clinical Settings, and Therapeutic Implications by Emma Zattarin, Rita Leporati, Francesca Ligorio, Riccardo Lobefaro, Andrea Vingiani, Giancarlo Pruneri, Claudio Vernieri

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Case Report: Prolonged clinical benefit with sequential trastuzumab-containing treatments in a patient with advanced extramammary Paget disease of the groin by Emma Zattarin, Federico Nichetti, Francesca Ligorio, Francesca Ligorio, Laura Mazzeo, Riccardo Lobefaro, Giovanni Fucà, Giorgia Peverelli, Andrea Vingiani, Andrea Vingiani, Giulia V. Bianchi, Giuseppe Capri, Filippo de Braud, Filippo de Braud, Claudio Vernieri, Claudio Vernieri

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Multidisciplinary management of pregnancy-associated and early post-partum head and neck cancer patients by Cristiana Bergamini, Stefano Cavalieri, Stefano Cavalieri, Carlo Resteghini, Salvatore Alfieri, Imperia Nuzzolese, Elena Colombo, Arianna Ottini, Giuseppina Calareso, Andrea Vingiani, Andrea Vingiani, Nicola Alessandro Iacovelli, Marzia Franceschini, Marco Guzzo, Alberto Deganello, Alberto Deganello, Lisa Licitra, Lisa Licitra

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Multigene signatures for early breast cancer in clinical practice: A report of the Lombardy genomic assays for breast cancer working group by Luca Licata, Luca Licata, Deborah Cosentini, Rita De Sanctis, Rita De Sanctis, Monica Iorfida, Elena Rota Caremoli, Andrea Vingiani, Andrea Vingiani, Edda Lucia Simoncini, Giancarlo Pruneri, Giancarlo Pruneri, Elisabetta Munzone, Giampaolo Bianchini, Giampaolo Bianchini, Alberto Zambelli, Alberto Zambelli, Carlo Tondini

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Moving HER2-low breast cancer predictive and prognostic data from clinical trials into the real world by Serena Di Cosimo, Eliana La Rocca, Eliana La Rocca, Silva Ljevar, Maria Carmen De Santis, Maria Carmen De Santis, Marta Bini, Marta Bini, Vera Cappelletti, Marta Valenti, Paolo Baili, Filippo G. de Braud, Filippo G. de Braud, Filippo G. de Braud, Secondo Folli, Gianfranco Scaperrotta, Gianfranco Scaperrotta, Chiara Volpi, Chiara Volpi, Chiara Volpi, Andrea Vingiani, Andrea Vingiani, Andrea Vingiani, Claudio Vernieri, Claudio Vernieri, Claudio Vernieri, Paolo Verderio, Rosalba Miceli, Giancarlo Pruneri, Giancarlo Pruneri, Giancarlo Pruneri

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Management of BRCA Tumour Testing in an Integrated Molecular Tumour Board Multidisciplinary Model by Jacopo Azzollini, Andrea Vingiani, Andrea Vingiani, Luca Agnelli, Luca Agnelli, Elena Tamborini, Federica Perrone, Elena Conca, Iolanda Capone, Adele Busico, Bernard Peissel, Erica Rosina, Monika Ducceschi, Mara Mantiero, Salvatore Lopez, Francesco Raspagliesi, Monica Niger, Matteo Duca, Silvia Damian, Claudia Proto, Filippo de Braud, Filippo de Braud, Giancarlo Pruneri, Giancarlo Pruneri, Siranoush Manoukian

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Prevalence of BRCA homopolymeric indels in an ION Torrent-based tumour-to-germline testing workflow in high-grade ovarian carcinoma by Jacopo Azzollini, Luca Agnelli, Elena Conca, Tommaso Torelli, Adele Busico, Iolanda Capone, Marta Angelini, Elena Tamborini, Federica Perrone, Andrea Vingiani, Daniele Lorenzini, Bernard Peissel, Giancarlo Pruneri, Siranoush Manoukian

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Hormone receptor status influences the impact of body mass index and hyperglycemia on the risk of tumor relapse in early-stage HER2-positive breast cancer patients by Francesca Ligorio, Luca Zambelli, Achille Bottiglieri, Lorenzo Castagnoli, Emma Zattarin, Riccardo Lobefaro, Arianna Ottini, Andrea Vingiani, Serenella M. Pupa, Giulia V. Bianchi, Giuseppe Capri, Giancarlo Pruneri, Filippo de Braud, Claudio Vernieri

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Endocrine-responsive lobular carcinoma of the breast: features associated with risk of late distant recurrence by Fabio Conforti, Laura Pala, Eleonora Pagan, Giuseppe Viale, Vincenzo Bagnardi, Giulia Peruzzotti, Tommaso De Pas, Nadia Bianco, Rossella Graffeo, Elena Guerini Rocco, Andrea Vingiani, Richard D. Gelber, Alan S. Coates, Marco Colleoni, Aron Goldhirsch

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Detecting gene copy number alterations by Oncomine Comprehensive genomic profiling in a comparative study on FFPE tumor samples by Fabio Bozzi, Elena Conca, Marco Silvestri, Gianpaolo Dagrada, Alice Ardore, Donata Penso, Daniele Lorenzini, Chiara Costanza Volpi, Desirè Viola Trupia, Adele Busico, Iolanda Capone, Federica Perrone, Elena Tamborini, Andrea Vingiani, Luca Agnelli, Giancarlo Pruneri

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A gene expression-based classifier for HER2-low breast cancer by Serena Di Cosimo, Sara Pizzamiglio, Chiara Maura Ciniselli, Valeria Duroni, Vera Cappelletti, Loris De Cecco, Cinzia De Marco, Marco Silvestri, Maria Carmen De Santis, Andrea Vingiani, Biagio Paolini, Rosaria Orlandi, Marilena Valeria Iorio, Giancarlo Pruneri, Paolo Verderio

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ESR1 gene amplification and MAP3K mutations are selected during adjuvant endocrine therapies in relapsing Hormone Receptor-positive, HER2-negative breast cancer (HR+ HER2- BC). by Lorenzo Ferrando, Andrea Vingiani, Anna Garuti, Claudio Vernieri, Antonino Belfiore, Luca Agnelli, Gianpaolo Dagrada, Diana Ivanoiu, Giuseppina Bonizzi, Elisabetta Munzone, Luana Lippolis, Martina Dameri, Francesco Ravera, Marco Colleoni, Giuseppe Viale, Luca Magnani, Alberto Ballestrero, Gabriele Zoppoli, Giancarlo Pruneri

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Targeted RNA-sequencing analysis for fusion transcripts detection in tumor diagnostics: assessment of bioinformatic tools reliability in FFPE samples by Iolanda Capone, Fabio Bozzi, Gian Paolo Dagrada, Paolo Verderio, Elena Conca, Adele Busico, Maria Adele Testi, Valentina Monti, Matteo Duca, Claudia Proto, Silvia Damian, Alberta Piccolo, Federica Perrone, Elena Tamborini, Andrea Devecchi, Paola Collini, Daniele Lorenzini, Andrea Vingiani, Luca Agnelli, Giancarlo Pruneri

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End-of-neoadjuvant treatment circulating microRNAs and HER2-positive breast cancer patient prognosis: An exploratory analysis from NeoALTTO by Serena Di Cosimo, Chiara M. Ciniselli, Sara Pizzamiglio, Vera Cappelletti, Marco Silvestri, Sarra El-Abed, Miguel Izquierdo, Mohammed Bajji, Paolo Nuciforo, Jens Huober, Jens Huober, David Cameron, Stephen Chia, Henry L. Gomez, Henry L. Gomez, Marilena V. Iorio, Andrea Vingiani, Giancarlo Pruneri, Paolo Verderio

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Bridging therapeutic opportunities: a survey by the Italian molecular tumor board workgroup of Alliance Against Cancer by Gennaro Ciliberto, Marco Canfora, Irene Terrenato, Chiara Agnoletto, Francesco Agustoni, Loredana Amoroso, Gustavo Baldassarre, Giuseppe Curigliano, Angelo Delmonte, Antonella De Luca, Michelangelo Fiorentino, Vanesa Gregorc, Toni Ibrahim, Chiara Lazzari, Angela Mastronuzzi, Paolo Pronzato, Armando Santoro, Giovanni Scambia, Stefania Tommasi, Andrea Vingiani, Patrizio Giacomini, Ruggero De Maria

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A cell-of-origin epigenetic tracer reveals clinically distinct subtypes of high-grade serous ovarian cancer by Pietro Lo Riso, Carlo Emanuele Villa, Gilles Gasparoni, Andrea Vingiani, Raffaele Luongo, Anna Manfredi, Annemarie Jungmann, Alessia Bertolotti, Francesca Borgo, Annalisa Garbi, Michela Lupia, Pasquale Laise, Vivek Das, Giancarlo Pruneri, Giuseppe Viale, Nicoletta Colombo, Teresa Manzo, Luigi Nezi, Ugo Cavallaro, Davide Cacchiarelli, Jörn Walter, Giuseppe Testa

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Association of a gene-expression subtype to outcome and treatment response in patients with recurrent/metastatic head and neck squamous cell carcinoma treated with nivolumab by Nerina Denaro, Lisa Licitra, Marco Merlano, Francesco Perri, Paolo Bossi, Cristina Gurizzan, Federica Perrone, Athanassios Argiris, Loris De Cecco, Stefano Cavalieri, Mara Serena Serafini, Federico Pistore, Deborah Lenoci, Silvana Canevari, Mario Airoldi, Maria Cossu Rocca, Primoz Strojan, Cvetka Grasic Kuhar, Andrea Vingiani, Maria Grazia Ghi, Alessandra Cassano, Giacomo Allegrini

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Tumor infiltrating lymphocyte stratification of prognostic staging of early-stage triple negative breast cancer by Sherene Loi, Roberto Salgado, Sylvia Adams, Giancarlo Pruneri, Prudence A. Francis, Magali Lacroix-Triki, Heikki Joensuu, Maria Vittoria Dieci, Sunil Badve, Sandra Demaria, Robert Gray, Elisabetta Munzone, Damien Drubay, Jerome Lemonnier, Christos Sotiriou, Pirkko Liisa Kellokumpu-Lehtinen, Andrea Vingiani, Kathryn Gray, Fabrice André, Carsten Denkert, Martine Piccart, Elvire Roblin, Stefan Michiels

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Peripheral blood lymphocytes predict clinical outcomes in hormone receptor-positive HER2-negative advanced breast cancer patients treated with CDK4/6 inhibitors by Emma Zattarin, Luigi Mariani, Alice Menichetti, Rita Leporati, Leonardo Provenzano, Francesca Ligorio, Giovanni Fucà, Riccardo Lobefaro, Luca Lalli, Andrea Vingiani, Federico Nichetti, Gaia Griguolo, Marianna Sirico, Ottavia Bernocchi, Antonio Marra, Chiara Corti, Paola Zagami, Elisa Agostinetto, Flavia Jacobs, Pierluigi Di Mauro, Daniele Presti, Caterina Sposetti, Carlo Alberto Giorgi, Valentina Guarneri, Rebecca Pedersini, Agnese Losurdo, Daniele Generali, Giuseppe Curigliano, Giancarlo Pruneri, Filippo de Braud, Maria Vittoria Dieci, Claudio Vernieri

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MGMT inactivation as a new biomarker in patients with advanced biliary tract cancers by Monica Niger, Federico Nichetti, Andrea Casadei‐Gardini, Federica Morano, Chiara Pircher, Elena Tamborini, Federica Perrone, Matteo Canale, Daniel B. Lipka, Andrea Vingiani, Luca Agnelli, Anna Dobberkau, Jennifer Hüllein, Felix Korell, Christoph E. Heilig, Sara Pusceddu, Francesca Corti, Michele Droz, Paola Ulivi, Michele Prisciandaro, Maria Antista, Marta Bini, Laura Cattaneo, Massimo Milione, Hanno Glimm, Bruno C. Köhler, Giancarlo Pruneri, Daniel Hübschmann, Stefan Fröhling, Vincenzo Mazzaferro, Filippo Pietrantonio, Maria Di Bartolomeo, Filippo deBraud

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