Does the world need germline editing for β-thalassemia? by Andreas E. Kulozik

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Gene Therapy of the Hemoglobinopathies by Joachim B. Kunz, Andreas E. Kulozik

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Odisha Revisited: A Personal Account by Graham R. Serjeant, Andreas E. Kulozik, Beryl E. Serjeant

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mRNA 3′end processing: A tale of the tail reaches the clinic by Ina Hollerer, Kerstin Grund, Matthias W. Hentze, Andreas E Kulozik

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The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay. by Niels H Gehring, Styliani Lamprinaki, Matthias W Hentze, Andreas E Kulozik

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P350: DAB1 EXPRESSION DRIVES PROLIFERATION AND METABOLIC ACTIVITY IN T-ALL AND INTERFERES WITH T-CELL-SPECIFIC PATHWAYS by Valentina Spleis, Büşra Erarslan-Uysal, Joachim Kunz, Tobias Rausch, Jan Korbel, Andreas E Kulozik

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Nonsense-mediated mRNA decay and loss-of-function of the protein underlie the X-linked epilepsy associated with the W356× mutation in synapsin I. by Maila Giannandrea, Fabrizia C Guarnieri, Niels H Gehring, Elena Monzani, Fabio Benfenati, Andreas E Kulozik, Flavia Valtorta

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Introduction of Universal Newborn Screening for Sickle Cell Disease in Germany—A Brief Narrative Review by Stephan Lobitz, Joachim B. Kunz, Holger Cario, Dani Hakimeh, Andrea Jarisch, Andreas E. Kulozik, Lena Oevermann, Regine Grosse

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Exon Junction Complexes Show a Distributional Bias toward Alternatively Spliced mRNAs and against mRNAs Coding for Ribosomal Proteins by Christian Hauer, Jana Sieber, Thomas Schwarzl, Ina Hollerer, Tomaz Curk, Anne-Marie Alleaume, Matthias W. Hentze, Andreas E. Kulozik

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NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia by Obul R. Bandapalli, Martin Zimmermann, Corinne Kox, Martin Stanulla, Martin Schrappe, Wolf-Dieter Ludwig, Rolf Koehler, Martina U. Muckenthaler, Andreas E. Kulozik

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HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA by Lara Ajamian, Karen Abel, Shringar Rao, Kishanda Vyboh, Francisco García-de-Gracia, Ricardo Soto-Rifo, Andreas E. Kulozik, Niels H. Gehring, Andrew J. Mouland

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Genetic modifiers of fetal hemoglobin affect the course of sickle cell disease in patients treated with hydroxyurea by Pierre Allard, Nareen Alhaj, Stephan Lobitz, Holger Cario, Andreas Jarisch, Regine Grosse, Lena Oevermann, Dani Hakimeh, Laura Tagliaferri, Elisabeth Kohne, Annette Kopp-Schneider, Andreas E. Kulozik, Joachim B. Kunz

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5‐azacytidine inhibits nonsense‐mediated decay in a MYC‐dependent fashion by Madhuri Bhuvanagiri, Joe Lewis, Kerstin Putzker, Jonas P Becker, Stefan Leicht, Jeroen Krijgsveld, Richa Batra, Brad Turnwald, Bogdan Jovanovic, Christian Hauer, Jana Sieber, Matthias W Hentze, Andreas E Kulozik

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Erratum to: Insights into the design and interpretation of iCLIP experiments by Nejc Haberman, Ina Huppertz, Jan Attig, Julian König, Zhen Wang, Christian Hauer, Matthias W. Hentze, Andreas E. Kulozik, Hervé Le Hir, Tomaž Curk, Christopher R. Sibley, Kathi Zarnack, Jernej Ule

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NMD inhibition by 5-azacytidine augments presentation of immunogenic frameshift-derived neoepitopes by Jonas P. Becker, Dominic Helm, Mandy Rettel, Frank Stein, Alejandro Hernandez-Sanchez, Katharina Urban, Johannes Gebert, Matthias Kloor, Gabriele Neu-Yilik, Magnus von Knebel Doeberitz, Matthias W. Hentze, Andreas E. Kulozik

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MAP3K7 is recurrently deleted in pediatric T-lymphoblastic leukemia and affects cell proliferation independently of NF-κB by David M. Cordas dos Santos, Juliane Eilers, Alfonso Sosa Vizcaino, Elena Orlova, Martin Zimmermann, Martin Stanulla, Martin Schrappe, Kathleen Börner, Dirk Grimm, Martina U. Muckenthaler, Andreas E. Kulozik, Joachim B. Kunz

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High CD45 surface expression determines relapse risk in children with precursor B-cell and T-cell acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol by Gunnar Cario, Peter Rhein, Rita Mitlöhner, Martin Zimmermann, Obul R. Bandapalli, Renja Romey, Anja Moericke, Wolf-Dieter Ludwig, Richard Ratei, Martina U. Muckenthaler, Andreas E. Kulozik, Martin Schrappe, Martin Stanulla, Leonid Karawajew

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P333: SUBCLONAL AND CLONAL VARIANTS IN TP53 AND KRAS COMBINED WITH POOR TREATMENT RESPONSE IDENTIFY A SUBGROUP OF ULTRA-HIGH-RISK PATIENTS OF PEDIATRIC T-LYMPHOBLASTIC LEUKEMIA (T-... by Tamara Kempter, Paulina Richter-Pechanska, Katarzyna Michel, Tobias Rausch, Büşra Erarslan-Uysal, Cornelia Eckert, Martin Zimmermann, Martin Stanulla, Martin Schrappe, Gunnar Cario, Renate Kirschner-Schwabe, Stefan Koehrer, Jan Korbel, Joachim Kunz, Andreas E Kulozik

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Subclonal TP53 and KRAS variants combined with poor treatment response identify ultrahigh-risk pediatric patients with T-ALL by Tamara Kempter, Paulina Richter-Pechańska, Katarzyna Michel, Tobias Rausch, Büşra Erarslan-Uysal, Cornelia Eckert, Martin Zimmermann, Martin Stanulla, Martin Schrappe, Gunnar Cario, Stefan Köhrer, Andishe Attarbaschi, Jan O. Korbel, Joachim B. Kunz, Andreas E. Kulozik

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Mutating heme oxygenase-1 into a peroxidase causes a defect in bilirubin synthesis associated with microcytic anemia and severe hyperinflammation by Johann Greil, Maria V. Verga-Falzacappa, Nicole E. Echner, Wolfgang Behnisch, Obul R. Bandapalli, Paulina Pechanska, Stephan Immenschuh, Vijith Vijayan, Jozsef Balla, Hirokatsu Tsukahara, Marion Schneider, Gritta Janka, Maren Claus, Thomas Longerich, Martina U. Muckenthaler, Andreas E. Kulozik

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