Title not available by Vasile Dragan, Gerhard Freiling, Andreas Hochhaus, Toader Morozan

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Targeting the phosphoinositide 3-kinase pathway in hematologic malignancies by Elias Jabbour, Oliver G. Ottmann, Michael Deininger, Andreas Hochhaus

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P683: TRIALS IN PROGRESS: FIRST-IN-HUMAN STUDY OF ELVN-001, A SELECTIVE BCR::ABL1 TYROSINE KINASE INHIBITOR, IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA WHO FAILED PREVIOUS TYROSINE... by Fabian Lang, Susan Branford, Joseph P. Lyssikatos, Helen Collins, Andreas Hochhaus

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Genomic Instability in Context of the Chromosomal Theory by Alice Fabarius, Peter Duesberg, Michelle Giehl, Wolfgang Seifarth, Andreas Hochhaus, Rüdiger Hehlmann

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EZH2 in Myeloid Malignancies by Jenny Rinke, Andrew Chase, Nicholas C. P. Cross, Andreas Hochhaus, Thomas Ernst

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P474: FUNCTIONAL (PHOSPHO-)PROTEOMICS OF DRUG RESPONSE IN ACUTE MYELOID LEUKEMIA by Denys Oliinyk, Maximilian Fleischmann, Dilfuza Ernafasova, Caroline Tschernjawski, Sebastian Scholl, Andreas Hochhaus, Florian Meier-Rosar

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PB1774: PHARMACOLOGICAL STRATEGIES TO OVERCOME RESISTANCE IN AML CELL LINE MODELS HARBORING ACTIVATING FLT3-ITD AND PTPN11 MUTATIONS by Maximilian Fleischmann, Nathalie Urban, Ole Hansen, Ulf Schnetzke, Florian Heidel, Andreas Hochhaus, Joerg Mueller, Sebastian Scholl

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PB1972: ASC4START: A PHASE IIIB, OPEN-LABEL, RANDOMIZED STUDY OF ASCIMINIB VERSUS NILOTINIB IN PATIENTS WITH NEWLY DIAGNOSED PH+ CHRONIC MYELOGENOUS LEUKEMIA IN CHRONIC PHASE by Andreas Hochhaus, Susanne Saussele, Francois-Xavier Mahon, Virginia Pilipovic, Yifan Zhang, Peter Schuld, Tim H Brümmendorf

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Impact of FLT3-ITD diversity on response to induction chemotherapy in patients with acute myeloid leukemia by Mike Fischer, Ulf Schnetzke, Bärbel Spies-Weisshart, Mario Walther, Maximilian Fleischmann, Inken Hilgendorf, Andreas Hochhaus, Sebastian Scholl

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ABL single nucleotide polymorphisms may masquerade as BCR-ABL mutations associated with resistance to tyrosine kinase inhibitors in patients with chronic myeloid leukemia by Thomas Ernst, Jana Hoffmann, Philipp Erben, Benjamin Hanfstein, Armin Leitner, Rüdiger Hehlmann, Andreas Hochhaus, Martin C. Müller

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Modulation of FLT3-ITD Localization and Targeting of Distinct Downstream Signaling Pathways as Potential Strategies to Overcome FLT3-Inhibitor Resistance by Maximilian Fleischmann, Mike Fischer, Ulf Schnetzke, Colin Fortner, Joanna Kirkpatrick, Florian H. Heidel, Andreas Hochhaus, Sebastian Scholl

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Polymorphisms of Dectin-1 and TLR2 Predispose to Invasive Fungal Disease in Patients with Acute Myeloid Leukemia. by Mike Fischer, Baerbel Spies-Weisshart, Karin Schrenk, Bernd Gruhn, Susan Wittig, Anita Glaser, Andreas Hochhaus, Sebastian Scholl, Ulf Schnetzke

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In Vivo Emergence of UL56 C325Y Cytomegalovirus Resistance to Letermovir in a Patient with Acute Myeloid Leukemia after Hematopoietic Cell Transplantation by Jochen J Frietsch, Detlef Michel, Thomas Stamminger, Friederike Hunstig, Sebastian Birndt, Ulf Schnetzke, Sebastian Scholl, Andreas Hochhaus, Inken Hilgendorf

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P960: EXTRAMEDULLARY MYELOMA REMAINS AN UNMET CLINICAL NEED EVEN IN THE ERA OF NOVEL AGENT. ANALYSIS OF THE SINGLE CENTER MCOHORT. by Annamaria Brioli, Franziska Braese, Olaposi Yomade, Inken Hilgendorf, Thomas Ernst, Theresa Maria Nägler, Andreas Hochhaus, Marie Von Lilienfeld-Toal

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Comparison of bone marrow high mitotic index metaphase fluorescence in situ hybridization to peripheral blood and bone marrow real time quantitative polymerase chain reaction on th... by Tuija Lundán, Vesa Juvonen, Martin C. Mueller, Satu Mustjoki, Taina Lakkala, Veli Kairisto, Andreas Hochhaus, Sakari Knuutila, Kimmo Porkka

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A polymorphism associated with STAT3 expression and response of chronic myeloid leukemia to interferon α by Sebastian Kreil, Katherine Waghorn, Thomas Ernst, Andrew Chase, Helen White, Rüdiger Hehlmann, Andreas Reiter, Andreas Hochhaus, Nicholas C.P. Cross

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Centrosome aberrations and G1 phase arrest after in vitro and in vivo treatment with the SRC/ABL inhibitor dasatinib by Alice Fabarius, Michelle Giehl, Blanka Rebacz, Alwin Krämer, Oliver Frank, Claudia Haferlach, Peter Duesberg, Rüdiger Hehlmann, Wolfgang Seifarth, Andreas Hochhaus

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Enhanced Bcr-Abl-specific antileukemic activity of arsenic trioxide through glutathione-depletion in imatinib-resistant cells by Heiko Konig, Nicolai Härtel, Beate Schultheis, Michael Schatz, Christian Lorentz, Junia V. Melo, Rüdiger Hehlmann, Andreas Hochhaus, Paul La Rosée

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The quantitative level of T315I mutated BCR-ABL predicts for major molecular response to second-line nilotinib or dasatinib treatment in patients with chronic myeloid leukemia by Thoralf Lange, Thomas Ernst, Franz X. Gruber, Jacqueline Maier, Michael Cross, Martin C. Müller, Dietger Niederwieser, Andreas Hochhaus, Markus Pfirrmann

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Dynamics of mutant BCR-ABL-positive clones after cessation of tyrosine kinase inhibitor therapy by Benjamin Hanfstein, Martin C. Müller, Sebastian Kreil, Thomas Ernst, Thomas Schenk, Christian Lorentz, Uwe Schwindel, Armin Leitner, Rüdiger Hehlmann, Andreas Hochhaus

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