Elimination of proliferating cells unmasks the shift from senescence to quiescence caused by rapamycin. by Olga V Leontieva, Zoya N Demidenko, Andrei V Gudkov, Mikhail V Blagosklonny

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Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit by Timothy V. Pyrkov, Konstantin Avchaciov, Andrei E. Tarkhov, Leonid I. Menshikov, Andrei V. Gudkov, Peter O. Fedichev

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Different effect of proteasome inhibition on vesicular stomatitis virus and poliovirus replication. by Nickolay Neznanov, Eugenia M Dragunsky, Konstantin M Chumakov, Lubov Neznanova, Ronald C Wek, Andrei V Gudkov, Amiya K Banerjee

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A flagellin-derived toll-like receptor 5 agonist stimulates cytotoxic lymphocyte-mediated tumor immunity. by Nicholas D Leigh, Guanglin Bian, Xilai Ding, Hong Liu, Semra Aygun-Sunar, Lyudmila G Burdelya, Andrei V Gudkov, Xuefang Cao

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Unsupervised learning of aging principles from longitudinal data by Konstantin Avchaciov, Marina P. Antoch, Ekaterina L. Andrianova, Andrei E. Tarkhov, Leonid I. Menshikov, Olga Burmistrova, Andrei V. Gudkov, Peter O. Fedichev

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Resistance of bone marrow stroma to genotoxic preconditioning is determined by p53 by Natalia Fedtsova, Elena A. Komarova, Kellee F. Greene, Liliya R. Novototskaya, Ivan Molodtsov, Craig M. Brackett, Evguenia Strom, Anatoli S. Gleiberman, Alexander N. Shakhov, Andrei V. Gudkov

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TLR5 agonist entolimod reduces the adverse toxicity of TNF while preserving its antitumor effects. by Gary J Haderski, Bojidar M Kandar, Craig M Brackett, Ilia M Toshkov, Christopher P Johnson, Geraldine M Paszkiewicz, Venkatesh Natarajan, Anatoli S Gleiberman, Andrei V Gudkov, Lyudmila G Burdelya

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Signaling through TLR5 mitigates lethal radiation damage by neutrophil-dependent release of MMP-9 by Craig M. Brackett, Kellee F. Greene, Alyssa R. Aldrich, Nicholas H. Trageser, Srabani Pal, Ivan Molodtsov, Bojidar M. Kandar, Lyudmila G. Burdelya, Scott I. Abrams, Andrei V. Gudkov

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Powerful Complex Immunoadjuvant Based on Synergistic Effect of Combined TLR4 and NOD2 Activation Significantly Enhances Magnitude of Humoral and Cellular Adaptive Immune Responses. by Amir I Tukhvatulin, Alina S Dzharullaeva, Natalia M Tukhvatulina, Dmitry V Shcheblyakov, Maxim M Shmarov, Inna V Dolzhikova, Patricia Stanhope-Baker, Boris S Naroditsky, Andrei V Gudkov, Denis Y Logunov, Alexander L Gintsburg

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TRAIN (Transcription of Repeats Activates INterferon) in response to chromatin destabilization induced by small molecules in mammalian cells by Katerina Leonova, Alfiya Safina, Elimelech Nesher, Poorva Sandlesh, Rachel Pratt, Catherine Burkhart, Brittany Lipchick, Ilya Gitlin, Costakis Frangou, Igor Koman, Jianmin Wang, Kirill Kirsanov, Marianna G Yakubovskaya, Andrei V Gudkov, Katerina Gurova

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The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates. by Vadim I Krivokrysenko, Ilia A Toshkov, Anatoli S Gleiberman, Peter Krasnov, Inna Shyshynova, Ivan Bespalov, Ratan K Maitra, Natalya V Narizhneva, Vijay K Singh, Mark H Whitnall, Andrei A Purmal, Alexander N Shakhov, Andrei V Gudkov, Elena Feinstein

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A deimmunized and pharmacologically optimized Toll-like receptor 5 agonist for therapeutic applications by Vadim Mett, Oleg V. Kurnasov, Ivan A. Bespalov, Ivan Molodtsov, Craig M. Brackett, Lyudmila G. Burdelya, Andrei A. Purmal, Anatoli S. Gleiberman, Ilia A. Toshkov, Catherine A. Burkhart, Yakov N. Kogan, Ekaterina L. Andrianova, Andrei V. Gudkov, Andrei L. Osterman

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A Purine Nucleotide Biosynthesis Enzyme Guanosine Monophosphate Reductase Is a Suppressor of Melanoma Invasion by Joseph A. Wawrzyniak, Anna Bianchi-Smiraglia, Wiam Bshara, Sudha Mannava, Jeff Ackroyd, Archis Bagati, Angela R. Omilian, Michael Im, Natalia Fedtsova, Jeffrey C. Miecznikowski, Kalyana C. Moparthy, Shoshanna N. Zucker, Qianqian Zhu, Nadezhda I. Kozlova, Albert E. Berman, Keith S. Hoek, Andrei V. Gudkov, Donna S. Shewach, Carl D. Morrison, Mikhail A. Nikiforov

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Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG by Anahid Ehteda, Sandy Simon, Laura Franshaw, Federico M. Giorgi, Jie Liu, Swapna Joshi, Jourdin R.C. Rouaen, Chi Nam Ignatius Pang, Ruby Pandher, Chelsea Mayoh, Yujie Tang, Aaminah Khan, Caitlin Ung, Ornella Tolhurst, Anne Kankean, Elisha Hayden, Rebecca Lehmann, Sylvie Shen, Anjana Gopalakrishnan, Peter Trebilcock, Katerina Gurova, Andrei V. Gudkov, Murray D. Norris, Michelle Haber, Orazio Vittorio, Maria Tsoli, David S. Ziegler

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The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression by Lin Xiao, Lin Xiao, Mawar Karsa, Mawar Karsa, Emma Ronca, Angelika Bongers, Angelika Kosciolek, Ali El-Ayoubi, Jezrael L. Revalde, Jezrael L. Revalde, Janith A. Seneviratne, Janith A. Seneviratne, Belamy B. Cheung, Belamy B. Cheung, Laurence C. Cheung, Laurence C. Cheung, Laurence C. Cheung, Rishi S. Kotecha, Rishi S. Kotecha, Rishi S. Kotecha, Rishi S. Kotecha, Andrea Newbold, Andrea Newbold, Stefan Bjelosevic, Stefan Bjelosevic, Greg M. Arndt, Greg M. Arndt, Greg M. Arndt, Richard B. Lock, Richard B. Lock, Ricky W. Johnstone, Ricky W. Johnstone, Andrei V. Gudkov, Katerina V. Gurova, Michelle Haber, Michelle Haber, Murray D. Norris, Murray D. Norris, Murray D. Norris, Michelle J. Henderson, Michelle J. Henderson, Klaartje Somers, Klaartje Somers

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