PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance by Merritt P Edlind, Andrew C Hsieh

Get full text

Patterns of chemotherapy use with primary radiotherapy for localized bladder cancer in patients 65 or older by Fady Ghali, Sarah K. Holt, Elizabeth L. Koehne, Jonathan J. Chen, Emily S. Weg, Jay J. Liao, Jing Zeng, Petros Grivas, Petros Grivas, Jessica E. Hawley, Jessica E. Hawley, Andrew C. Hsieh, Andrew C. Hsieh, Robert Bruce Montgomery, Robert Bruce Montgomery, Jonathan L. Wright, Jonathan L. Wright

Get full text

mRNA translation is a therapeutic vulnerability necessary for bladder epithelial transformation by Sujata Jana, Rucha Deo, Rowan P. Hough, Yuzhen Liu, Jessie L. Horn, Jonathan L. Wright, Hung-Ming Lam, Kevin R. Webster, Gary G. Chiang, Nahum Sonenberg, Andrew C. Hsieh

Get full text

The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs. by Danielle C Hamm, Ellen M Paatela, Sean R Bennett, Chao-Jen Wong, Amy E Campbell, Cynthia L Wladyka, Andrew A Smith, Sujatha Jagannathan, Andrew C Hsieh, Stephen J Tapscott

Get full text

Multiplexed functional genomic analysis of 5’ untranslated region mutations across the spectrum of prostate cancer by Yiting Lim, Sonali Arora, Samantha L. Schuster, Lukas Corey, Matthew Fitzgibbon, Cynthia L. Wladyka, Xiaoying Wu, Ilsa M. Coleman, Jeffrey J. Delrow, Eva Corey, Lawrence D. True, Peter S. Nelson, Gavin Ha, Andrew C. Hsieh

Get full text

Multi-level functional genomics reveals molecular and cellular oncogenicity of patient-based 3′ untranslated region mutations by Samantha L. Schuster, Sonali Arora, Cynthia L. Wladyka, Pushpa Itagi, Lukas Corey, Dave Young, Bethany L. Stackhouse, Lori Kollath, Qian V. Wu, Eva Corey, Lawrence D. True, Gavin Ha, Patrick J. Paddison, Andrew C. Hsieh

Get full text

A bladder cancer patient-derived xenograft displays aggressive growth dynamics in vivo and in organoid culture by Elise Y. Cai, Jose Garcia, Yuzhen Liu, Funda Vakar-Lopez, Sonali Arora, Holly M. Nguyen, Bryce Lakely, Lisha Brown, Alicia Wong, Bruce Montgomery, John K. Lee, Eva Corey, Jonathan L. Wright, Andrew C. Hsieh, Hung-Ming Lam

Get full text

N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis by Daniel A. Kuppers, Sonali Arora, Yiting Lim, Andrea R. Lim, Lucas M. Carter, Philip D. Corrin, Christopher L. Plaisier, Ryan Basom, Jeffrey J. Delrow, Shiyan Wang, Housheng Hansen He, Beverly Torok-Storb, Andrew C. Hsieh, Patrick J. Paddison

Get full text

Defining the therapeutic selective dependencies for distinct subtypes of PI3K pathway-altered prostate cancers by Ninghui Mao, Zeda Zhang, Young Sun Lee, Danielle Choi, Aura Agudelo Rivera, Dan Li, Cindy Lee, Samuel Haywood, Xiaoping Chen, Qing Chang, Guotai Xu, Hsuan-An Chen, Elisa de Stanchina, Charles Sawyers, Neal Rosen, Andrew C. Hsieh, Yu Chen, Brett S. Carver

Get full text

Defining cellular population dynamics at single-cell resolution during prostate cancer progression by Alexandre A Germanos, Sonali Arora, Ye Zheng, Erica T Goddard, Ilsa M Coleman, Anson T Ku, Scott Wilkinson, Hanbing Song, Nicholas J Brady, Robert A Amezquita, Michael Zager, Annalysa Long, Yu Chi Yang, Jason H Bielas, Raphael Gottardo, David S Rickman, Franklin W Huang, Cyrus M Ghajar, Peter S Nelson, Adam G Sowalsky, Manu Setty, Andrew C Hsieh

Get full text

Increased translation driven by non-canonical EZH2 creates a synthetic vulnerability in enzalutamide-resistant prostate cancer by Shankha S. Chatterjee, Juan F. Linares, Tania Cid-Diaz, Angeles Duran, Mohd. Imran K. Khan, Marta Osrodek, Nicholas J. Brady, Miguel Reina-Campos, Antonio Marzio, Varadha Balaji Venkadakrishnan, Martin K. Bakht, Francesca Khani, Juan Miguel Mosquera, Brian D. Robinson, Jenna Moyer, Olivier Elemento, Andrew C. Hsieh, David W. Goodrich, David S. Rickman, Himisha Beltran, Jorge Moscat, Maria T. Diaz-Meco

Get full text

Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer by Meixia Che, Aashi Chaturvedi, Sarah A. Munro, Samuel P. Pitzen, Alex Ling, Weijie Zhang, Josh Mentzer, Sheng-Yu Ku, Loredana Puca, Yanyun Zhu, Andries M. Bergman, Tesa M. Severson, Colleen Forster, Yuzhen Liu, Jacob Hildebrand, Mark Daniel, Ting-You Wang, Luke A. Selth, Theresa Hickey, Amina Zoubeidi, Martin Gleave, Rohan Bareja, Andrea Sboner, Wayne Tilley, Jason S. Carroll, Winston Tan, Manish Kohli, Rendong Yang, Andrew C. Hsieh, Paari Murugan, Wilbert Zwart, Himisha Beltran, R. Stephanie Huang, Scott M. Dehm

Get full text