Imd pathway-specific immune assays reveal NF-κB stimulation by viral RNA PAMPs in Aedes aegypti Aag2 cells. ανά Tiffany A Russell, Andalus Ayaz, Andrew D Davidson, Ana Fernandez-Sesma, Kevin Maringer

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High-throughput quantitative proteomic analysis of dengue virus type 2 infected A549 cells. ανά Han-Chen Chiu, Holger Hannemann, Kate J Heesom, David A Matthews, Andrew D Davidson

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The Genetic Stability, Replication Kinetics and Cytopathogenicity of Recombinant Avian Coronaviruses with a T16A or an A26F Mutation within the E Protein Is Cell-Type Dependent ανά Isobel Webb, Sarah Keep, Kieran Littolff, Jamie Stuart, Graham Freimanis, Paul Britton, Andrew D. Davidson, Helena J. Maier, Erica Bickerton

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The fatty acid site is coupled to functional motifs in the SARS-CoV-2 spike protein and modulates spike allosteric behaviour ανά A. Sofia F. Oliveira, Deborah K. Shoemark, Amaurys Avila Ibarra, Andrew D. Davidson, Imre Berger, Christiane Schaffitzel, Adrian J. Mulholland

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Cell Type Variability in the Incorporation of Lipids in the Dengue Virus Virion ανά Atitaya Hitakarun, Maia Kavanagh Williamson, Nathamon Yimpring, Wannapa Sornjai, Nitwara Wikan, Christopher J. Arthur, Julien Pompon, Andrew D. Davidson, Duncan R. Smith

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Limitations of using feline coronavirus spike protein gene mutations to diagnose feline infectious peritonitis ανά Emily N. Barker, Angelica Stranieri, Chris R. Helps, Emily L. Porter, Andrew D. Davidson, Michael J. Day, Toby Knowles, Anja Kipar, Séverine Tasker

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Ambient carbon dioxide concentration correlates with SARS-CoV-2 aerostability and infection risk ανά Allen Haddrell, Henry Oswin, Mara Otero-Fernandez, Joshua F. Robinson, Tristan Cogan, Robert Alexander, Jamie F. S. Mann, Darryl Hill, Adam Finn, Andrew D. Davidson, Jonathan P. Reid

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Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein ανά Andrew D. Davidson, Maia Kavanagh Williamson, Sebastian Lewis, Deborah Shoemark, Miles W. Carroll, Kate J. Heesom, Maria Zambon, Joanna Ellis, Philip A. Lewis, Julian A. Hiscox, David A. Matthews

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Reverse genetics of SARS-related coronavirus using vaccinia virus-based recombination. ανά Sjoerd H E van den Worm, Klara Kristin Eriksson, Jessika C Zevenhoven, Friedemann Weber, Roland Züst, Thomas Kuri, Ronald Dijkman, Guohui Chang, Stuart G Siddell, Eric J Snijder, Volker Thiel, Andrew D Davidson

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TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction. ανά Hataf Khan, Helena Winstone, Jose M Jimenez-Guardeño, Carl Graham, Katie J Doores, Caroline Goujon, David A Matthews, Andrew D Davidson, Suzannah J Rihn, Massimo Palmarini, Stuart J D Neil, Michael H Malim

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Mucin Transiently Sustains Coronavirus Infectivity through Heterogenous Changes in Phase Morphology of Evaporating Aerosol ανά Robert W. Alexander, Jianghan Tian, Allen E. Haddrell, Henry P. Oswin, Edward Neal, Daniel A. Hardy, Mara Otero-Fernandez, Jamie F. S. Mann, Tristan A. Cogan, Adam Finn, Andrew D. Davidson, Darryl J. Hill, Jonathan P. Reid

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Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2 ανά Kapil Gupta, Christine Toelzer, Maia Kavanagh Williamson, Deborah K. Shoemark, A. Sofia F. Oliveira, David A. Matthews, Abdulaziz Almuqrin, Oskar Staufer, Sathish K. N. Yadav, Ufuk Borucu, Frederic Garzoni, Daniel Fitzgerald, Joachim Spatz, Adrian J. Mulholland, Andrew D. Davidson, Christiane Schaffitzel, Imre Berger

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Development of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbone ανά Xiao-Feng Li, Hao-Long Dong, Hong-Jiang Wang, Xing-Yao Huang, Ye-Feng Qiu, Xue Ji, Qing Ye, Chunfeng Li, Yang Liu, Yong-Qiang Deng, Tao Jiang, Gong Cheng, Fu-Chun Zhang, Andrew D. Davidson, Ya-Jun Song, Pei-Yong Shi, Cheng-Feng Qin

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An ACAT inhibitor suppresses SARS-CoV-2 replication and boosts antiviral T cell activity. ανά Peter A C Wing, Nathalie M Schmidt, Rory Peters, Maximilian Erdmann, Rachel Brown, Hao Wang, Leo Swadling, COVIDsortium Investigators, Joseph Newman, Nazia Thakur, Kaho Shionoya, Sophie B Morgan, Timothy Sc Hinks, Koichi Watashi, Dalan Bailey, Scott B Hansen, Andrew D Davidson, Mala K Maini, Jane A McKeating

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Prolonged T-cell activation and long COVID symptoms independently associate with severe COVID-19 at 3 months ανά Marianna Santopaolo, Michaela Gregorova, Fergus Hamilton, David Arnold, Anna Long, Aurora Lacey, Elizabeth Oliver, Alice Halliday, Holly Baum, Kristy Hamilton, Rachel Milligan, Olivia Pearce, Lea Knezevic, Begonia Morales Aza, Alice Milne, Emily Milodowski, Eben Jones, Rajeka Lazarus, Anu Goenka, Adam Finn, Nicholas Maskell, Andrew D Davidson, Kathleen Gillespie, Linda Wooldridge, Laura Rivino

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The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity ανά Hazel Stewart, Yongxu Lu, Sarah O’Keefe, Anusha Valpadashi, Luis Daniel Cruz-Zaragoza, Hendrik A. Michel, Samantha K. Nguyen, George W. Carnell, Nina Lukhovitskaya, Rachel Milligan, Yasmin Adewusi, Irwin Jungreis, Valeria Lulla, David A. Matthews, Stephen High, Peter Rehling, Edward Emmott, Jonathan L. Heeney, Andrew D. Davidson, James R. Edgar, Geoffrey L. Smith, Andrew E. Firth

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Post-acute COVID-19 associated with evidence of bystander T-cell activation and a recurring antibiotic-resistant bacterial pneumonia ανά Michaela Gregorova, Daniel Morse, Tarcisio Brignoli, Joseph Steventon, Fergus Hamilton, Mahableshwar Albur, David Arnold, Matthew Thomas, Alice Halliday, Holly Baum, Christopher Rice, Matthew B Avison, Andrew D Davidson, Marianna Santopaolo, Elizabeth Oliver, Anu Goenka, Adam Finn, Linda Wooldridge, Borko Amulic, Rosemary J Boyton, Daniel M Altmann, David K Butler, Claire McMurray, Joanna Stockton, Sam Nicholls, Charles Cooper, Nicholas Loman, Michael J Cox, Laura Rivino, Ruth C Massey

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Amplicon and Metagenomic Analysis of Middle East Respiratory Syndrome (MERS) Coronavirus and the Microbiome in Patients with Severe MERS ανά Waleed Aljabr, Muhannad Alruwaili, Rebekah Penrice-Randal, Abdulrahman Alrezaihi, Abbie Jasmine Harrison, Yan Ryan, Eleanor Bentley, Benjamin Jones, Bader Y. Alhatlani, Dayel AlShahrani, Zana Mahmood, Natasha Y. Rickett, Bandar Alosaimi, Asif Naeem, Saad Alamri, Hadel Alsran, Maaweya E. Hamed, Xiaofeng Dong, Abdullah M. Assiri, Abdullah R. Alrasheed, Muaawia Hamza, Miles W. Carroll, Matthew Gemmell, Alistair Darby, I’ah Donovan-Banfield, James P. Stewart, David A. Matthews, Andrew D. Davidson, Julian A. Hiscox

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The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection ανά Hannah Goldswain, Xiaofeng Dong, Rebekah Penrice-Randal, Muhannad Alruwaili, Ghada T. Shawli, Tessa Prince, Maia Kavanagh Williamson, Jayna Raghwani, Nadine Randle, Benjamin Jones, I’ah Donovan-Banfield, Francisco J. Salguero, Julia A. Tree, Yper Hall, Catherine Hartley, Maximilian Erdmann, James Bazire, Tuksin Jearanaiwitayakul, Malcolm G. Semple, Peter J. M. Openshaw, J. Kenneth Baillie, ISARIC4C Investigators, Stevan R. Emmett, Paul Digard, David A. Matthews, Lance Turtle, Alistair C. Darby, Andrew D. Davidson, Miles W. Carroll, Julian A. Hiscox

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Evaluation and deployment of isotype-specific salivary antibody assays for detecting previous SARS-CoV-2 infection in children and adults ανά Amy C. Thomas, Elizabeth Oliver, Holly E. Baum, Kapil Gupta, Kathryn L. Shelley, Anna E. Long, Hayley E. Jones, Joyce Smith, Benjamin Hitchings, Natalie di Bartolo, Kate Vasileiou, Fruzsina Rabi, Hanin Alamir, Malak Eghleilib, Ore Francis, Jennifer Oliver, Begonia Morales-Aza, Ulrike Obst, Debbie Shattock, Rachael Barr, Lucy Collingwood, Kaltun Duale, Niall Grace, Guillaume Gonnage Livera, Lindsay Bishop, Harriet Downing, Fernanda Rodrigues, Nicholas Timpson, Caroline L. Relton, Ashley Toye, Derek N. Woolfson, Imre Berger, Anu Goenka, Andrew D. Davidson, Kathleen M. Gillespie, Alistair J. K. Williams, Mick Bailey, Ellen Brooks-Pollock, Adam Finn, Alice Halliday, the CoMMinS Study Team

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