The Gut Microbiome, Microsatellite Status and the Response to Immunotherapy in Colorectal Cancer by Toritseju O. Sillo, Andrew D. Beggs, Gary Middleton, Akinfemi Akingboye

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Radiosensitising Cancer Using Phosphatidylinositol-3-Kinase (PI3K), Protein Kinase B (AKT) or Mammalian Target of Rapamycin (mTOR) Inhibitors by Kasun Wanigasooriya, Robert Tyler, Joao D. Barros-Silva, Yashashwi Sinha, Tariq Ismail, Andrew D. Beggs

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Meta‐analysis of the demographic and prognostic significance of gastrointestinal symptoms in COVID‐19 patients by Shafquat Zaman, Shahin Hajibandeh, Shahab Hajibandeh, Ali Yasen Y Mohamedahmed, Mohammed E El‐Asrag, Nabil Quraishi, Tariq H Iqbal, Andrew D Beggs

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Patient Derived Organoids Confirm That PI3K/AKT Signalling Is an Escape Pathway for Radioresistance and a Target for Therapy in Rectal Cancer by Kasun Wanigasooriya, Kasun Wanigasooriya, Joao D. Barros-Silva, Louise Tee, Mohammed E. El-asrag, Agata Stodolna, Oliver J. Pickles, Oliver J. Pickles, Joanne Stockton, Claire Bryer, Rachel Hoare, Celina M. Whalley, Robert Tyler, Robert Tyler, Toritseju Sillo, Toritseju Sillo, Christopher Yau, Tariq Ismail, Andrew D. Beggs, Andrew D. Beggs

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Systematic review of donor and recipient predictive biomarkers of response to faecal microbiota transplantation in patients with ulcerative colitis by Nia Paddison Rees, Walaa Shaheen, Christopher Quince, Chris Tselepis, Richard D Horniblow, Naveen Sharma, Andrew D Beggs, Tariq H Iqbal, Mohammed Nabil Quraishi

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Mental health symptoms in a cohort of hospital healthcare workers following the first peak of the COVID-19 pandemic in the UK by Kasun Wanigasooriya, Priyanka Palimar, David N. Naumann, Khalida Ismail, Jodie L. Fellows, Peter Logan, Christopher V. Thompson, Helen Bermingham, Andrew D. Beggs, Tariq Ismail

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The chromatin insulator CTCF regulates HPV18 transcript splicing and differentiation-dependent late gene expression. by Jack Ferguson, Karen Campos-León, Ieisha Pentland, Joanne D Stockton, Thomas Günther, Andrew D Beggs, Adam Grundhoff, Sally Roberts, Boris Noyvert, Joanna L Parish

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Pancreatic Exocrine Insufficiency and the Gut Microbiome in Pancreatic Cancer: A Target for Future Diagnostic Tests and Therapies? by James M. Halle-Smith, Lewis A. Hall, Sarah F. Powell-Brett, Nabeel Merali, Adam E. Frampton, Andrew D. Beggs, Paul Moss, Keith J. Roberts

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The chromatin insulator CTCF regulates HPV18 transcript splicing and differentiation-dependent late gene expression by Jack Ferguson, Karen Campos-León, Ieisha Pentland, Joanne D. Stockton, Thomas Günther, Andrew D. Beggs, Adam Grundhoff, Sally Roberts, Boris Noyvert, Joanna L. Parish

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Ultra-Low DNA Input into Whole Genome Methylation Assays and Detection of Oncogenic Methylation and Copy Number Variants in Circulating Tumour DNA by Celina Whalley, Karl Payne, Enric Domingo, Andrew Blake, Susan Richman, Jill Brooks, Nikolaos Batis, Rachel Spruce, S-CORT Consortium, Hisham Mehanna, Paul Nankivell, Andrew D. Beggs

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Involvement of the Gut Microbiome in the Local and Systemic Immune Response to Pancreatic Ductal Adenocarcinoma by James M. Halle-Smith, Hayden Pearce, Samantha Nicol, Lewis A. Hall, Sarah F. Powell-Brett, Andrew D. Beggs, Tariq Iqbal, Paul Moss, Keith J. Roberts

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Multi-modality detection of SARS-CoV-2 in faecal donor samples for transplantation and in asymptomatic emergency surgical admissions [version 1; peer review: 2 approved] by Susan E. Manzoor, Shafquat Zaman, Celina Whalley, David Inglis, Andrew Bosworth, Michael Kidd, Sahida Shabir, Nabil Quraishi, Christopher A. Green, Tariq Iqbal, Andrew D. Beggs

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Differences in the On- and Off-Tumor Microbiota between Right- and Left-Sided Colorectal Cancer by Oliver Phipps, Mohammed N. Quraishi, Edward A. Dickson, Helen Steed, Aditi Kumar, Austin G. Acheson, Andrew D. Beggs, Matthew J. Brookes, Hafid Omar Al-Hassi

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Complete response to neoadjuvant chemoradiotherapy in rectal cancer is associated with RAS/AKT mutations and high tumour mutational burden by Joanne D. Stockton, Louise Tee, Celina Whalley, Jonathan James, Mark Dilworth, Rachel Wheat, Thomas Nieto, S-CORT Consortium, Ian Geh, João D. Barros-Silva, Andrew D. Beggs

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Loss of expression and promoter methylation of SLIT2 are associated with sessile serrated adenoma formation. by Andrew D Beggs, Angela Jones, Neil Shepherd, Abed Arnaout, Caroline Finlayson, A Muti Abulafi, Dion G Morton, Glenn M Matthews, Shirley V Hodgson, Ian P M Tomlinson

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Oral and Intravenous Iron Therapy Differentially Alter the On- and Off-Tumor Microbiota in Anemic Colorectal Cancer Patients by Oliver Phipps, Hafid O. Al-Hassi, Mohammed N. Quraishi, Edward A. Dickson, Jonathan Segal, Helen Steed, Aditi Kumar, Austin G. Acheson, Andrew D. Beggs, Matthew J. Brookes

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Circulating tumour DNA detects somatic variants contributing to spatial and temporal intra-tumoural heterogeneity in head and neck squamous cell carcinoma by Karl F. B. Payne, Peter Brotherwood, Harini Suriyanarayanan, Jill M. Brooks, Nikolaos Batis, Andrew D. Beggs, Deena M. A. Gendoo, Deena M. A. Gendoo, Hisham Mehanna, Paul Nankivell

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Clinical-grade whole-genome sequencing and 3′ transcriptome analysis of colorectal cancer patients by Agata Stodolna, Miao He, Mahesh Vasipalli, Zoya Kingsbury, Jennifer Becq, Joanne D. Stockton, Mark P. Dilworth, Jonathan James, Toju Sillo, Daniel Blakeway, Stephen T. Ward, Tariq Ismail, Mark T. Ross, Andrew D. Beggs

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Mechanisms of synthetic lethality between BRCA1/2 and 53BP1 deficiencies and DNA polymerase theta targeting by George E. Ronson, Katarzyna Starowicz, Elizabeth J. Anthony, Ann Liza Piberger, Lucy C. Clarke, Alexander J. Garvin, Andrew D. Beggs, Celina M. Whalley, Matthew J. Edmonds, James F. J. Beesley, Joanna R. Morris

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Validation of epigenetic markers to identify colitis associated cancer: Results of module 1 of the ENDCAP-C studyResearch in context by Andrew D. Beggs, Samir Mehta, Jonathan J. Deeks, Jonathan D. James, Germaine M. Caldwell, Mark P. Dilworth, Joanne D. Stockton, Daniel Blakeway, Valerie Pestinger, Alexandra Vince, Phillipe Taniere, Tariq Iqbal, Laura Magill, Glenn Matthews, Dion G. Morton

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