Hypermethylation of nc886 in HPV-positive oropharyngeal cancer and its clinical implications: An epigenome-wide association study by Yifan Xu, Ziqiao Wang, Peng Wei, Richa Gairola, Karl T. Kelsey, Andrew G. Sikora, Guojun Li, Jian Gu

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Metformin generates profound alterations in systemic and tumor immunity with associated antitumor effects by Ratna Veeramachaneni, Wangjie Yu, Jared M Newton, Jan O Kemnade, Heath D Skinner, Andrew G Sikora, Vlad C Sandulache

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Characterizing treatment resistance in muscle invasive bladder cancer using the chicken egg chorioallantoic membrane patient-derived xenograft model by Hugo Villanueva, Gabrielle A. Wells, Malachi T. Miller, Mariana Villanueva, Ravi Pathak, Patricia Castro, Michael M. Ittmann, Andrew G. Sikora, Seth P. Lerner

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GWAS-identified telomere length associated genetic variants predict risk of recurrence of HPV-positive oropharyngeal cancer after definitive radiotherapyResearch in context by Peng Sun, Peng Wei, Hongliang Liu, Jia Wu, Neil D. Gross, Andrew G. Sikora, Qingyi Wei, Sanjay Shete, Mark E. Zafereo, Jisheng Liu, Guojun Li

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Non-Invasive Radiofrequency Field Treatment of 4T1 Breast Tumors Induces T-cell Dependent Inflammatory Response by Jared M. Newton, Jose H. Flores-Arredondo, Sarah Suki, Matthew J. Ware, Martyna Krzykawska-Serda, Mahdi Agha, Justin J. Law, Andrew G. Sikora, Steven A. Curley, Stuart J. Corr

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The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC) by Andrew G. Sikora, Kevin J. Harrington, R. Bryan Bell, Maura L. Gillison, Quynh-Thu Le, Nancy Y. Lee, Rebecca L. Lewis, Loren K. Mell, Adam Raben, Ravindra Uppaluri, Fernanda Whitworth, Dan P. Zandberg

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Glutathione peroxidase 2 is a metabolic driver of the tumor immune microenvironment and immune checkpoint inhibitor response by Defeng Deng, Ratna Veeramachaneni, Andrew G Sikora, Vlad C Sandulache, William K Decker, Kazi Mokim Ahmed, Nagireddy Putluri, Vasanta Putluri, Maria F Cardenas, David A Wheeler, Andy I Frederick, Sawad Kazi, Mitchell J Frederick

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Caspase-8 loss radiosensitizes head and neck squamous cell carcinoma to SMAC mimetic–induced necroptosis by Burak Uzunparmak, Meng Gao, Antje Lindemann, Kelly Erikson, Li Wang, Eric Lin, Steven J. Frank, Frederico O. Gleber-Netto, Mei Zhao, Heath D. Skinner, Jared Newton, Andrew G. Sikora, Jeffrey N. Myers, Curtis R. Pickering

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TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiothe... by Padmini Jayaraman, Falguni Parikh, Jared M. Newton, Aurelie Hanoteau, Charlotte Rivas, Rosemarie Krupar, Kimal Rajapakshe, Ravi Pathak, Kavin Kanthaswamy, Cassie MacLaren, Shixia Huang, Cristian Coarfa, Chad Spanos, Dean P. Edwards, Robin Parihar, Andrew G. Sikora

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Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition by Jared M. Newton, Aurelie Hanoteau, Hsuan-Chen Liu, Angelina Gaspero, Falguni Parikh, Robyn D. Gartrell-Corrado, Thomas D. Hart, Damya Laoui, Jo A. Van Ginderachter, Neeraja Dharmaraj, William C. Spanos, Yvonne Saenger, Simon Young, Andrew G. Sikora

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Tobacco exposure as a major modifier of oncologic outcomes in human papillomavirus (HPV) associated oropharyngeal squamous cell carcinoma by Hesham Elhalawani, Abdallah S. R. Mohamed, Baher Elgohari, Timothy A. Lin, Andrew G. Sikora, Stephen Y. Lai, Abdelrahman Abusaif, Jack Phan, William H. Morrison, G. Brandon Gunn, David I. Rosenthal, Adam S. Garden, Clifton D. Fuller, Vlad C. Sandulache

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Anti-tumor immunity induced by ectopic expression of viral antigens is transient and limited by immune escape by Neeraja Dharmaraj, Stacey L. Piotrowski, Chen Huang, Jared M. Newton, Leonard S. Golfman, Aurelie Hanoteau, Sandeep T. Koshy, Aileen W. Li, Merlyn X. Pulikkathara, Bing Zhang, Jared K. Burks, David J. Mooney, Yu L. Lei, Andrew G. Sikora, Simon Young

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Mutant p53 drives an immune cold tumor immune microenvironment in oral squamous cell carcinoma by Yewen Shi, Tongxin Xie, Bingbing Wang, Rong Wang, Yu Cai, Bo Yuan, Frederico O. Gleber-Netto, Xiangjun Tian, Alanis E. Rodriguez-Rosario, Abdullah A. Osman, Jing Wang, Curtis R. Pickering, Xiaoyong Ren, Andrew G. Sikora, Jeffrey N. Myers, Roberto Rangel

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TP53 gain-of-function mutation modulates the immunosuppressive microenvironment in non-HPV-associated oral squamous cell carcinoma by Bo Yuan, Xi Chen, Wenyi Wang, Ratna Veeramachaneni, Andrew G Sikora, Yewen Shi, Xiaoyong Ren, Shaolong Cao, Fabio Henrique Brasil da Costa, Alanis E Rodriguez Rosario, Arnoldo Corona, Chieko Michikawa, Abdullah A Osman, Tongxin Xie, Jeffrey N Myers, Roberto Rangel

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Tumor microenvironment modulation enhances immunologic benefit of chemoradiotherapy by Aurelie Hanoteau, Jared M. Newton, Rosemarie Krupar, Chen Huang, Hsuan-Chen Liu, Angelina Gaspero, Robyn D. Gartrell, Yvonne M. Saenger, Thomas D. Hart, Saskia J. Santegoets, Damya Laoui, Chad Spanos, Falguni Parikh, Padmini Jayaraman, Bing Zhang, Sjoerd H. Van der Burg, Jo A. Van Ginderachter, Cornelis J. M. Melief, Andrew G. Sikora

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