Evaluation of Gene Expression Data From Cybrids and Tumours Highlights Elevated -Driven Proliferation in Triple-Negative Breast Cancer by Akanksha Mishra, Maria Bonello, Adam Byron, Simon P Langdon, Andrew H Sims

Get full text

T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity by Marta Canel, David Taggart, Andrew H Sims, David W Lonergan, Irene C Waizenegger, Alan Serrels

Get full text

Increased STAT1 signaling in endocrine-resistant breast cancer. by Rui Huang, Dana Faratian, Andrew H Sims, Danielle Wilson, Jeremy S Thomas, David J Harrison, Simon P Langdon

Get full text

On-treatment biomarkers can improve prediction of response to neoadjuvant chemotherapy in breast cancer by Richard J. Bownes, Arran K. Turnbull, Carlos Martinez-Perez, David A. Cameron, Andrew H. Sims, Olga Oikonomidou

Get full text

Sprouty 2 is an independent prognostic factor in breast cancer and may be useful in stratifying patients for trastuzumab therapy. by Dana Faratian, Andrew H Sims, Peter Mullen, Charlene Kay, Inhwa Um, Simon P Langdon, David J Harrison

Get full text

Correction: An Model That Recapitulates the Epithelial to Mesenchymal Transition (EMT) in Human Breast Cancer. by Elad Katz, Sylvie Dubois-Marshall, Andrew H. Sims, Philippe Gautier, Helen Caldwell, Richard R. Meehan, David J. Harrison

Get full text

Correction: An Model That Recapitulates the Epithelial to Mesenchymal Transition (EMT) in Human Breast Cancer. by Elad Katz, Sylvie Dubois-Marshall, Andrew H. Sims, Philippe Gautier, Helen Caldwell, Richard R. Meehan, David J. Harrison

Get full text

Correction: An Model That Recapitulates the Epithelial to Mesenchymal Transition (EMT) in Human Breast Cancer. by Elad Katz, Sylvie Dubois-Marshall, Andrew H. Sims, Philippe Gautier, Helen Caldwell, Richard R. Meehan, David J. Harrison

Get full text

HER2 regulates HIF-2α and drives an increased hypoxic response in breast cancer by Edward J. Jarman, Carol Ward, Arran K. Turnbull, Carlos Martinez-Perez, James Meehan, Chrysi Xintaropoulou, Andrew H. Sims, Simon P. Langdon

Get full text

The G Protein-Coupled Estrogen Receptor (GPER) Expression Correlates with Pro-Metastatic Pathways in ER-Negative Breast Cancer: A Bioinformatics Analysis by Marianna Talia, Ernestina Marianna De Francesco, Damiano Cosimo Rigiracciolo, Maria Grazia Muoio, Lucia Muglia, Antonino Belfiore, Marcello Maggiolini, Andrew H. Sims, Rosamaria Lappano

Get full text

Functional Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling by Ian M. Overton, Andrew H. Sims, Jeremy A. Owen, Bret S. E. Heale, Matthew J. Ford, Alexander L. R. Lubbock, Erola Pairo-Castineira, Abdelkader Essafi

Get full text

Molecular changes during extended neoadjuvant letrozole treatment of breast cancer: distinguishing acquired resistance from dormant tumours by Cigdem Selli, Arran K. Turnbull, Dominic A. Pearce, Ang Li, Anu Fernando, Jimi Wills, Lorna Renshaw, Jeremy S. Thomas, J. Michael Dixon, Andrew H. Sims

Get full text

Activation of the S100A7/RAGE Pathway by IGF-1 Contributes to Angiogenesis in Breast Cancer by Maria Grazia Muoio, Marianna Talia, Rosamaria Lappano, Andrew H. Sims, Veronica Vella, Francesca Cirillo, Livia Manzella, Marika Giuliano, Marcello Maggiolini, Antonino Belfiore, Ernestina Marianna De Francesco

Get full text

PIK3CA genotype and a PIK3CA mutation-related gene signature and response to everolimus and letrozole in estrogen receptor positive breast cancer. by Sherene Loi, Stefan Michiels, Jose Baselga, John M S Bartlett, Sandeep K Singhal, Vicky S Sabine, Andrew H Sims, Tarek Sahmoud, J Michael Dixon, Martine J Piccart, Christos Sotiriou

Get full text

Correction: PIK3CA Genotype and a PIK3CA Mutation-Related Gene Signature and Response to Everolimus and Letrozole in Estrogen Receptor Positive Breast Cancer. by Sherene Loi, Stefan Michiels, Jose Baselga, John M S Bartlett, Sandeep K Singhal, Vicky S Sabine, Andrew H Sims, Tarek Sahmoud, J Michael Dixon, Martine J Piccart, Christos Sotiriou

Get full text

Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations by Robert L. Hollis, Alison M. Meynert, Michael Churchman, Tzyvia Rye, Melanie Mackean, Fiona Nussey, Mark J. Arends, Andrew H. Sims, Colin A. Semple, C. Simon Herrington, Charlie Gourley

Get full text

Development of mouse models of angiosarcoma driven by p53 by Donald M. Salter, Meredyth Griffin, Morwenna Muir, Katy Teo, Jayne Culley, James R. Smith, Laura Gomez-Cuadrado, Kylie Matchett, Andrew H. Sims, Larry Hayward, Neil C. Henderson, Valerie G. Brunton

Get full text

Characterisation of the Stromal Microenvironment in Lobular Breast Cancer by Laura Gómez-Cuadrado, Esme Bullock, Zeanap Mabruk, Hong Zhao, Margarita Souleimanova, Pernille Rimmer Noer, Arran K. Turnbull, Claus Oxvig, Nicholas Bertos, Adam Byron, J. Michael Dixon, Morag Park, Syed Haider, Rachael Natrajan, Andrew H. Sims, Valerie G. Brunton

Get full text

Author Correction: MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures by Tanmoy Mondal, Santhilal Subhash, Roshan Vaid, Stefan Enroth, Sireesha Uday, Björn Reinius, Sanhita Mitra, Arif Mohammed, Alva Rani James, Emily Hoberg, Aristidis Moustakas, Ulf Gyllensten, Steven J. M. Jones, Claes M. Gustafsson, Andrew H. Sims, Fredrik Westerlund, Eduardo Gorab, Chandrasekhar Kanduri

Get full text

Novel Mechanisms of Tumor Promotion by the Insulin Receptor Isoform A in Triple-Negative Breast Cancer Cells by Veronica Vella, Marika Giuliano, Alessandro La Ferlita, Michele Pellegrino, Germano Gaudenzi, Salvatore Alaimo, Michele Massimino, Alfredo Pulvirenti, Alessandra Dicitore, Paolo Vigneri, Giovanni Vitale, Roberta Malaguarnera, Andrea Morrione, Andrew H. Sims, Alfredo Ferro, Marcello Maggiolini, Rosamaria Lappano, Ernestina Marianna De Francesco, Antonino Belfiore

Get full text