Michaelis-like complex of SARS-CoV-2 main protease visualized by room-temperature X-ray crystallography by Daniel W. Kneller, Qiu Zhang, Leighton Coates, John M. Louis, Andrey Kovalevsky

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The Neutron Macromolecular Crystallography Instruments at Oak Ridge National Laboratory: Advances, Challenges, and Opportunities by Flora Meilleur, Leighton Coates, Matthew J. Cuneo, Andrey Kovalevsky, Dean A. A. Myles

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Identification and structural analysis of a thermophilic β-1,3-glucanase from compost by Jianwei Feng, Shenyuan Xu, Ruirui Feng, Andrey Kovalevsky, Xia Zhang, Dongyang Liu, Qun Wan

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Autoprocessing and oxyanion loop reorganization upon GC373 and nirmatrelvir binding of monomeric SARS-CoV-2 main protease catalytic domain by Nashaat T. Nashed, Daniel W. Kneller, Leighton Coates, Rodolfo Ghirlando, Annie Aniana, Andrey Kovalevsky, John M. Louis

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Insights into the mechanism of SARS-CoV-2 main protease autocatalytic maturation from model precursors by Annie Aniana, Nashaat T. Nashed, Rodolfo Ghirlando, Leighton Coates, Daniel W. Kneller, Andrey Kovalevsky, John M. Louis

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Room-temperature X-ray crystallography reveals the oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL Mpro: insights into enzyme mechanism and drug design by Daniel W. Kneller, Gwyndalyn Phillips, Hugh M. O'Neill, Kemin Tan, Andrzej Joachimiak, Leighton Coates, Andrey Kovalevsky

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Substrate Binding Stiffens Aspartate Aminotransferase by Altering the Enzyme Picosecond Vibrational Dynamics by Steven Dajnowicz, Yongqiang Cheng, Luke L. Daemen, Kevin L. Weiss, Oksana Gerlits, Timothy C. Mueser, Andrey Kovalevsky

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Visualizing Tetrahedral Oxyanion Bound in HIV‑1 Protease Using Neutrons: Implications for the Catalytic Mechanism and Drug Design by Mukesh Kumar, Kalyaneswar Mandal, Matthew P. Blakeley, Troy Wymore, Stephen B. H. Kent, John M. Louis, Amit Das, Andrey Kovalevsky

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Structural plasticity of SARS-CoV-2 3CL Mpro active site cavity revealed by room temperature X-ray crystallography by Daniel W. Kneller, Gwyndalyn Phillips, Hugh M. O’Neill, Robert Jedrzejczak, Lucy Stols, Paul Langan, Andrzej Joachimiak, Leighton Coates, Andrey Kovalevsky

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Revealing protonation states and tracking substrate in serine hydroxymethyltransferase with room-temperature X-ray and neutron crystallography by Victoria N. Drago, Claudia Campos, Mattea Hooper, Aliyah Collins, Oksana Gerlits, Kevin L. Weiss, Matthew P. Blakeley, Robert S. Phillips, Andrey Kovalevsky

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Direct visualization of critical hydrogen atoms in a pyridoxal 5′-phosphate enzyme by Steven Dajnowicz, Ryne C. Johnston, Jerry M. Parks, Matthew P. Blakeley, David A. Keen, Kevin L. Weiss, Oksana Gerlits, Andrey Kovalevsky, Timothy C. Mueser

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Covalent narlaprevir- and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease by Daniel W. Kneller, Hui Li, Gwyndalyn Phillips, Kevin L. Weiss, Qiu Zhang, Mark A. Arnould, Colleen B. Jonsson, Surekha Surendranathan, Jyothi Parvathareddy, Matthew P. Blakeley, Leighton Coates, John M. Louis, Peter V. Bonnesen, Andrey Kovalevsky

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Structural and functional characterization of NEMO cleavage by SARS-CoV-2 3CLpro by Mikhail A. Hameedi, Erica T. Prates, Michael R. Garvin, Irimpan I. Mathews, B. Kirtley Amos, Omar Demerdash, Mark Bechthold, Mamta Iyer, Simin Rahighi, Daniel W. Kneller, Andrey Kovalevsky, Stephan Irle, Van-Quan Vuong, Julie C. Mitchell, Audrey Labbe, Stephanie Galanie, Soichi Wakatsuki, Daniel Jacobson

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