Dynamics and variability in the pleiotropic effects of adaptation in laboratory budding yeast populations by Christopher W Bakerlee, Angela M Phillips, Alex N Nguyen Ba, Michael M Desai

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Hierarchical sequence-affinity landscapes shape the evolution of breadth in an anti-influenza receptor binding site antibody by Angela M Phillips, Daniel P Maurer, Caelan Brooks, Thomas Dupic, Aaron G Schmidt, Michael M Desai

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Enhanced ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin by Angela M Phillips, Michael B Doud, Luna O Gonzalez, Vincent L Butty, Yu-Shan Lin, Jesse D Bloom, Matthew D Shoulders

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Binding affinity landscapes constrain the evolution of broadly neutralizing anti-influenza antibodies by Angela M Phillips, Katherine R Lawrence, Alief Moulana, Thomas Dupic, Jeffrey Chang, Milo S Johnson, Ivana Cvijovic, Thierry Mora, Aleksandra M Walczak, Michael M Desai

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The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution by Alief Moulana, Thomas Dupic, Angela M Phillips, Jeffrey Chang, Anne A Roffler, Allison J Greaney, Tyler N Starr, Jesse D Bloom, Michael M Desai

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Compensatory epistasis maintains ACE2 affinity in SARS-CoV-2 Omicron BA.1 by Alief Moulana, Thomas Dupic, Angela M. Phillips, Jeffrey Chang, Serafina Nieves, Anne A. Roffler, Allison J. Greaney, Tyler N. Starr, Jesse D. Bloom, Michael M. Desai

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Host proteostasis modulates influenza evolution by Angela M Phillips, Luna O Gonzalez, Emmanuel E Nekongo, Anna I Ponomarenko, Sean M McHugh, Vincent L Butty, Stuart S Levine, Yu-Shan Lin, Leonid A Mirny, Matthew D Shoulders

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Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones. by Angela M Phillips, Anna I Ponomarenko, Kenny Chen, Orr Ashenberg, Jiayuan Miao, Sean M McHugh, Vincent L Butty, Charles A Whittaker, Christopher L Moore, Jesse D Bloom, Yu-Shan Lin, Matthew D Shoulders

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The endoplasmic reticulum proteostasis network profoundly shapes the protein sequence space accessible to HIV envelope. by Jimin Yoon, Emmanuel E Nekongo, Jessica E Patrick, Tiffani Hui, Angela M Phillips, Anna I Ponomarenko, Samuel J Hendel, Rebecca M Sebastian, Yu Meng Zhang, Vincent L Butty, C Brandon Ogbunugafor, Yu-Shan Lin, Matthew D Shoulders

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Phenotypic and molecular evolution across 10,000 generations in laboratory budding yeast populations by Milo S Johnson, Shreyas Gopalakrishnan, Juhee Goyal, Megan E Dillingham, Christopher W Bakerlee, Parris T Humphrey, Tanush Jagdish, Elizabeth R Jerison, Katya Kosheleva, Katherine R Lawrence, Jiseon Min, Alief Moulana, Angela M Phillips, Julia C Piper, Ramya Purkanti, Artur Rego-Costa, Michael J McDonald, Alex N Nguyen Ba, Michael M Desai

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