Editorial: Novel approaches to targeting the vasculature and metabolome to prevent brain aging and related diseases gan Jennifer Ihuoma, Jennifer Ihuoma, Sharon Negri, Sharon Negri, Amanda Morato Do Canto, Anika M. S. Hartz, Anika M. S. Hartz, Aditi Deshpande, Stefano Tarantini, Stefano Tarantini, Stefano Tarantini

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Proteasome inhibition protects blood–brain barrier P-glycoprotein and lowers Aβ brain levels in an Alzheimer’s disease model gan Milica Vulin, Yu Zhong, Bryan J. Maloney, Björn Bauer, Anika M. S. Hartz

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Oxidative stress alters mitochondrial homeostasis in isolated brain capillaries gan Gopal V. Velmurugan, Hemendra J. Vekaria, Anika M.S. Hartz, Björn Bauer, W. Brad Hubbard

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Plasma S100β is a predictor for pathology and cognitive decline in Alzheimer’s disease gan Geetika Nehra, Bryan J. Maloney, Rebecca R. Smith, Wijitra Chumboatong, Erin L. Abner, Peter T. Nelson, Björn Bauer, Anika M. S. Hartz

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Cognitive decline, Aβ pathology, and blood–brain barrier function in aged 5xFAD mice gan Geetika Nehra, Sasivimon Promsan, Ruedeemars Yubolphan, Wijitra Chumboatong, Pornpun Vivithanaporn, Bryan J. Maloney, Anusorn Lungkaphin, Bjoern Bauer, Anika M. S. Hartz

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