TNFa and IL2 Encoding Oncolytic Adenovirus Activates Pathogen and Danger-Associated Immunological Signaling by Camilla Heiniö, Riikka Havunen, Joao Santos, Klaas de Lint, Victor Cervera-Carrascon, Anna Kanerva, Akseli Hemminki

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Systemic Delivery of Oncolytic Adenovirus to Tumors Using Tumor-Infiltrating Lymphocytes as Carriers by Joao Santos, Camilla Heiniö, Dafne Quixabeira, Sadia Zafar, James Clubb, Santeri Pakola, Victor Cervera-Carrascon, Riikka Havunen, Anna Kanerva, Akseli Hemminki

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Effective Combination Immunotherapy with Oncolytic Adenovirus and Anti-PD-1 for Treatment of Human and Murine Ovarian Cancers by Camilla Heiniö, James Clubb, Tatiana Kudling, Dafne Quixabeira, Victor Cervera-Carrascon, Riikka Havunen, Susanna Grönberg-Vähä-Koskela, João Manuel Santos, Johanna Tapper, Anna Kanerva, Akseli Hemminki

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Oncolytic adenovirus decreases the proportion of TIM-3+ subset of tumor-infiltrating CD8+ T cells with correlation to improved survival in patients with cancer by Matti Kankainen, Timo Joensuu, Akseli Hemminki, Juuso Juhila, Siri Tähtinen, Otto Hemminki, Anna Kanerva, Kristian Taipale, Ilkka Liikanen, Minna Oksanen, Dafne C A Quixabeira, Saru Basnet

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Oncolytic adenovirus shapes the ovarian tumor microenvironment for potent tumor-infiltrating lymphocyte tumor reactivity by Akseli Hemminki, Víctor Cervera-Carrascón, Mikko Siurala, Riikka Havunen, Sadia Zafar, Tanja de Gruijl, Anna Kanerva, João Manuel Santos, Camilla Heiniö, Dafne C A Quixabeira, Ralf Butzow, Heini Lassus

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Local therapy with an engineered oncolytic adenovirus enables antitumor response in non-injected melanoma tumors in mice treated with aPD-1 by Dafne C. A. Quixabeira, Victor Cervera-Carrascon, Joao M. Santos, James H.A. Clubb, Tatiana V. Kudling, Saru Basnet, Camilla Heiniö, Susanna Grönberg-Vähä-Koskela, Marjukka Anttila, Riikka Havunen, Anna Kanerva, Akseli Hemminki

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806 Oncolytic adenovirus coding for human Mucin1 T cell engager with interleukin-2 potentiates anti-tumor T cell responses against tumors by Akseli Hemminki, Anna Kanerva, João Manuel Santos, Saru Basnet, Santeri A Pakola, James Clubb, Elise Jirovec, Tatiana Kudling, Lyna Haybout, Mirte Van der Heijden, Susanna AM Grönberg-Vähä-Koskela, Victor Arias, Dafne Alves Quixabeira

Oncolytic adenovirus coding for bispecific T cell engager against human MUC-1 potentiates T cell response against solid tumors by Saru Basnet, Joao M. Santos, Dafne C.A. Quixabeira, James H.A. Clubb, Susanna A.M. Grönberg-Vähä-Koskela, Victor Arias, Santeri Pakola, Tatiana V. Kudling, Camilla Heiniö, Riikka Havunen, Victor Cervera-Carrascon, Suvi Sorsa, Marjukka Anttila, Anna Kanerva, Akseli Hemminki

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Effective intravenous delivery of adenovirus armed with TNFα and IL-2 improves anti-PD-1 checkpoint blockade in non-small cell lung cancer by Tatiana V. Kudling, James H.A. Clubb, Santeri Pakola, Dafne C.A. Quixabeira, Iris A.K. Lähdeniemi, Camilla Heiniö, Victor Arias, Riikka Havunen, Victor Cervera-Carrascon, Joao M. Santos, Eva Sutinen, Jari Räsänen, Kristian Borenius, Mikko I. Mäyränpää, Eero Aaltonen, Suvi Sorsa, Otto Hemminki, Anna Kanerva, Emmy W. Verschuren, Ilkka Ilonen, Akseli Hemminki

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814 Enhancing anti-tumor response in ICI-refractory non-small cell lung cancer through intravenous administration of oncolytic adenovirus armed with hTNFα and hIL-2 in combination... by Akseli Hemminki, Víctor Cervera-Carrascón, Riikka Havunen, Otto Hemminki, Anna Kanerva, João Manuel Santos, Camilla Heiniö, Jari Räsänen, Suvi Sorsa, Santeri A Pakola, James Clubb, Tatiana V Kudling, Susanna AM Grönberg-Vähä-Koskela, Victor Arias, Dafne Alves Quixabeira, Iris Lähdeniemi, Eva Sutinen, Kristian Borenius, Mikko Mäyränpää, Eero Altonen, Emmy W Verschuren, Ilkka Ilonen

Single intravenous administration of oncolytic adenovirus TILT-123 results in systemic tumor transduction and immune response in patients with advanced solid tumors by Elise Jirovec, Dafne C. A. Quixabeira, James H. A. Clubb, Santeri A. Pakola, Tatiana Kudling, Victor Arias, Lyna Haybout, Katriina Jalkanen, Tuomo Alanko, Tine Monberg, Amir Khammari, Brigitte Dreno, Inge Marie Svane, Matthew S. Block, Daniel A. Adamo, Johanna Mäenpää, Claudia Kistler, Suvi Sorsa, Otto Hemminki, Anna Kanerva, João M. Santos, Victor Cervera-Carrascon, Akseli Hemminki

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Local delivery of interleukin 7 with an oncolytic adenovirus activates tumor-infiltrating lymphocytes and causes tumor regression by Tatiana V. Kudling, James H.A. Clubb, Dafne C.A. Quixabeira, Joao M. Santos, Riikka Havunen, Alexander Kononov, Camilla Heiniö, Victor Cervera-Carrascon, Santeri Pakola, Saru Basnet, Susanna Grönberg-Vähä-Koskela, Victor Arias, Ivan Gladwyn-Ng, Katri Aro, Leif Bäck, Jari Räsänen, Ilkka Ilonen, Kristian Borenius, Mikko Räsänen, Otto Hemminki, Antti Rannikko, Anna Kanerva, Johanna Tapper, Akseli Hemminki

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Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting by James H. A. Clubb, James H. A. Clubb, James H. A. Clubb, Tatiana V. Kudling, Tatiana V. Kudling, Mykhailo Girych, Lyna Haybout, Lyna Haybout, Santeri Pakola, Santeri Pakola, Firas Hamdan, Firas Hamdan, Víctor Cervera-Carrascon, Víctor Cervera-Carrascon, Víctor Cervera-Carrascon, Annabrita Hemmes, Susanna Grönberg-Vähä-Koskela, Susanna Grönberg-Vähä-Koskela, Susanna Grönberg-Vähä-Koskela, João Manuel Santos, João Manuel Santos, João Manuel Santos, Dafne C. A. Quixabeira, Dafne C. A. Quixabeira, Dafne C. A. Quixabeira, Saru Basnet, Saru Basnet, Camilla Heiniö, Camilla Heiniö, Victor Arias, Victor Arias, Elise Jirovec, Elise Jirovec, Shreyas Kaptan, Riikka Havunen, Riikka Havunen, Riikka Havunen, Suvi Sorsa, Suvi Sorsa, Suvi Sorsa, Abdullah Erikat, Joel Schwartz, Marjukka Anttila, Katri Aro, Katri Aro, Tapani Viitala, Ilpo Vattulainen, Vincenzo Cerullo, Vincenzo Cerullo, Anna Kanerva, Akseli Hemminki, Akseli Hemminki, Akseli Hemminki, Akseli Hemminki

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