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Lady Byrne
Anne-Marie, Lady Byrne is a fictional character from the
BBC medical drama ''
Holby City'', portrayed by actress
Jane Asher. The character first appeared on 10 May 2007 in episode "After the Fall" -
series 9, episode 30 of the programme. After several guest appearances as the mother of established character
Joseph Byrne throughout series 9 and
10, Asher signed a three-month contract to become a series regular from May 2008 onwards, for a period of 10 episodes. Her initial storyline saw her son's girlfriend,
Jac Naylor, embark on an affair with Anne-Marie's husband and Joseph's father,
Lord Byrne - eventually culminating in his death, and leaving the character a widow. Upon her return to the programme, she takes over Lord Byrne's position as
Executive Chairman of the Byrne Foundation – a charity committed to research into
Cardiac Valve Disease.
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