Sigma-2 Receptors—From Basic Biology to Therapeutic Target: A Focus on Age-Related Degenerative Diseases by Britney N. Lizama, Jennifer Kahle, Susan M. Catalano, Anthony O. Caggiano, Michael Grundman, Mary E. Hamby

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rHIgM22 enhances remyelination in the brain of the cuprizone mouse model of demyelination by Ariana P. Mullin, Charlene Cui, Yu Wang, Jing Wang, Erika Troy, Anthony O. Caggiano, Tom J. Parry, Raymond W. Colburn, Elias Pavlopoulos

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A pilot study to evaluate the effect of CT1812 treatment on synaptic density and other biomarkers in Alzheimer’s disease by Christopher H. van Dyck, Adam P. Mecca, Ryan S. O’Dell, Hugh H. Bartlett, Nina G. Diepenbrock, Yiyun Huang, Mary E. Hamby, Michael Grundman, Susan M. Catalano, Anthony O. Caggiano, Richard E. Carson

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Intravenous glial growth factor 2 (GGF2) isoform of neuregulin-1β improves left ventricular function, gene and protein expression in rats after myocardial infarction. by Michael F Hill, Amish V Patel, Abigail Murphy, Holly M Smith, Cristi L Galindo, Laura Pentassuglia, Xuyang Peng, Carrie G Lenneman, Oghenerukevwe Odiete, David B Friedman, Marvin W Kronenberg, Siyuen Zheng, Zhongming Zhao, Yanna Song, Frank E Harrell, Maya Srinivas, Anindita Ganguly, Jennifer Iaci, Tom J Parry, Anthony O Caggiano, Douglas B Sawyer

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A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer’s disease using an indwelling CSF catheter by Kelsie M. LaBarbera, Yvette I. Sheline, Nicholas J. Izzo, Carla M. Yuede, Lora Waybright, Raymond Yurko, Hannah M. Edwards, Woodrow D. Gardiner, Kaj Blennow, Henrik Zetterberg, Anne Börjesson-Hanson, Roger Morgan, Charles S. Davis, Robert J. Guttendorf, Lon S. Schneider, Steven DeKosky, Harry LeVine, Michael Grundman, Anthony O. Caggiano, John R. Cirrito, Susan M. Catalano, Mary E. Hamby

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A Phase I, Single Ascending Dose Study of Cimaglermin Alfa (Neuregulin 1β3) in Patients With Systolic Dysfunction and Heart Failure by Daniel J. Lenihan, MD, Sarah A. Anderson, ACNP, Carrie Geisberg Lenneman, MD, Evan Brittain, MD, MSCI, James A.S. Muldowney, III, MD, Lisa Mendes, MD, Ping Z. Zhao, PhD, Jennifer Iaci, MS, Stephen Frohwein, MD, Ronald Zolty, MD, PhD, Andrew Eisen, MD, PhD, Douglas B. Sawyer, MD, PhD, Anthony O. Caggiano, MD, PhD

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