5 Severely immunodeficient NOG-EXL mice allow for humanization and development of a human glioblastoma-derived tumor microenvironment by Cecile Alanio, Zev Binder, Donald O’Rourke, Charles-Antoine Assenmacher, Lamia Lamrani, Anthony Secreto, Nicholas Skuli, Moriah Jacobson, Elinor Willis, Enrico Radaelli, Maclean Nasrallah