Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts. by Aimy Sebastian, Nicholas R Hum, Deepa K Murugesh, Sarah Hatsell, Aris N Economides, Gabriela G Loots

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Application of a novel strategy of engineering conditional alleles to a single exon gene, Sox2. by Nikolaos Mandalos, Marannia Saridaki, Jessica Lea Harper, Anastasia Kotsoni, Peter Yang, Aris N Economides, Eumorphia Remboutsika

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The Bulk of Autotaxin Activity Is Dispensable for Adult Mouse Life. by Aggeliki Katsifa, Eleanna Kaffe, Nefeli Nikolaidou-Katsaridou, Aris N Economides, Susan Newbigging, Colin McKerlie, Vassilis Aidinis

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Odd skipped-related 1 (Osr1) identifies muscle-interstitial fibro-adipogenic progenitors (FAPs) activated by acute injury by Jürgen Stumm, Pedro Vallecillo-García, Sophie Vom Hofe-Schneider, David Ollitrault, Heinrich Schrewe, Aris N. Economides, Giovanna Marazzi, David A. Sassoon, Sigmar Stricker

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How Activin A Became a Therapeutic Target in Fibrodysplasia Ossificans Progressiva by Dushyanth Srinivasan, Martin Arostegui, Erich J. Goebel, Kaitlin N. Hart, Senem Aykul, John B. Lees-Shepard, Vincent Idone, Sarah J. Hatsell, Aris N. Economides

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Interactions between BMP-7 and USAG-1 (uterine sensitization-associated gene-1) regulate supernumerary organ formations. by Honoka Kiso, Katsu Takahashi, Kazuyuki Saito, Yumiko Togo, Hiroko Tsukamoto, Boyen Huang, Manabu Sugai, Akira Shimizu, Yasuhiko Tabata, Aris N Economides, Harold C Slavkin, Kazuhisa Bessho

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Bmp7 maintains undifferentiated kidney progenitor population and determines nephron numbers at birth. by Mayumi Tomita, Misako Asada, Nariaki Asada, Jin Nakamura, Akiko Oguchi, Atsuko Y Higashi, Shuichiro Endo, Elizabeth Robertson, Takeshi Kimura, Toru Kita, Aris N Economides, Jordan Kreidberg, Motoko Yanagita

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Odd skipped-related 1 controls the pro-regenerative response of fibro-adipogenic progenitors by Georgios Kotsaris, Taimoor H. Qazi, Christian H. Bucher, Hafsa Zahid, Sophie Pöhle-Kronawitter, Vladimir Ugorets, William Jarassier, Stefan Börno, Bernd Timmermann, Claudia Giesecke-Thiel, Aris N. Economides, Fabien Le Grand, Pedro Vallecillo-García, Petra Knaus, Sven Geissler, Sigmar Stricker

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Skeletal phenotype amelioration in mucopolysaccharidosis VI requires intervention at the earliest stages of postnatal development by Elizabeth Hwang-Wong, Gabrielle Amar, Nanditha Das, Xiaoli Zhang, Nina Aaron, Kirsten Gale, Nyanza Rothman, Massimo Fante, Andrew Baik, Ajay Bhargava, Arun Fricker, Michelle McAlister, Jeremy Rabinowitz, John Lees-Shepard, Kalyan Nannuru, Aris N. Economides, Katherine D. Cygnar

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Twisted gastrulation, a BMP antagonist, exacerbates podocyte injury. by Sachiko Yamada, Jin Nakamura, Misako Asada, Masayuki Takase, Taiji Matsusaka, Taku Iguchi, Ryo Yamada, Mari Tanaka, Atsuko Y Higashi, Tomohiko Okuda, Nariaki Asada, Atsushi Fukatsu, Hiroshi Kawachi, Daniel Graf, Eri Muso, Toru Kita, Takeshi Kimura, Ira Pastan, Aris N Economides, Motoko Yanagita

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Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva by Eleanor Williams, Jana Bagarova, Georgina Kerr, Dong-Dong Xia, Elsie S. Place, Devaveena Dey, Yue Shen, Geoffrey A. Bocobo, Agustin H. Mohedas, Xiuli Huang, Philip E. Sanderson, Arthur Lee, Wei Zheng, Aris N. Economides, James C. Smith, Paul B. Yu, Alex N. Bullock

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Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1 by Senem Aykul, Lily Huang, Lili Wang, Nanditha M. Das, Sandra Reisman, Yonaton Ray, Qian Zhang, Nyanza Rothman, Kalyan C. Nannuru, Vishal Kamat, Susannah Brydges, Luca Troncone, Laura Johnsen, Paul B. Yu, Sergio Fazio, John Lees-Shepard, Kevin Schutz, Andrew J. Murphy, Aris N. Economides, Vincent Idone, Sarah J. Hatsell

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Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loop by Senem Aykul, Richard A Corpina, Erich J Goebel, Camille J Cunanan, Alexandra Dimitriou, Hyon Jong Kim, Qian Zhang, Ashique Rafique, Raymond Leidich, Xin Wang, Joyce McClain, Johanna Jimenez, Kalyan C Nannuru, Nyanza J Rothman, John B Lees-Shepard, Erik Martinez-Hackert, Andrew J Murphy, Thomas B Thompson, Aris N Economides, Vincent Idone

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Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes by Parsa Akbari, Olukayode A. Sosina, Jonas Bovijn, Karl Landheer, Jonas B. Nielsen, Minhee Kim, Senem Aykul, Tanima De, Mary E. Haas, George Hindy, Nan Lin, Ian R. Dinsmore, Jonathan Z. Luo, Stefanie Hectors, Benjamin Geraghty, Mary Germino, Lampros Panagis, Prodromos Parasoglou, Johnathon R. Walls, Gabor Halasz, Gurinder S. Atwal, Regeneron Genetics Center, DiscovEHR Collaboration, Marcus Jones, Michelle G. LeBlanc, Christopher D. Still, David J. Carey, Alice Giontella, Marju Orho-Melander, Jaime Berumen, Pablo Kuri-Morales, Jesus Alegre-Díaz, Jason M. Torres, Jonathan R. Emberson, Rory Collins, Daniel J. Rader, Brian Zambrowicz, Andrew J. Murphy, Suganthi Balasubramanian, John D. Overton, Jeffrey G. Reid, Alan R. Shuldiner, Michael Cantor, Goncalo R. Abecasis, Manuel A. R. Ferreira, Mark W. Sleeman, Viktoria Gusarova, Judith Altarejos, Charles Harris, Aris N. Economides, Vincent Idone, Katia Karalis, Giusy Della Gatta, Tooraj Mirshahi, George D. Yancopoulos, Olle Melander, Jonathan Marchini, Roberto Tapia-Conyer, Adam E. Locke, Aris Baras, Niek Verweij, Luca A. Lotta

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