Bicyclic azetidines target acute and chronic stages of Toxoplasma gondii by inhibiting parasite phenylalanyl t-RNA synthetase by Joshua B. Radke, Bruno Melillo, Payal Mittal, Manmohan Sharma, Amit Sharma, Yong Fu, Taher Uddin, Arthur Gonse, Eamon Comer, Stuart L. Schreiber, Anil K. Gupta, Arnab K. Chatterjee, L. David Sibley

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A small molecule UPR modulator for diabetes identified by high throughput screening by Valeria Marrocco, Tuan Tran, Siying Zhu, Seung Hyuk Choi, Ana M. Gamo, Sijia Li, Qiangwei Fu, Marta Diez Cunado, Jason Roland, Mitch Hull, Van Nguyen-Tran, Sean Joseph, Arnab K. Chatterjee, Nikki Rogers, Matthew S. Tremblay, Weijun Shen

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Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease. by Shilpi Khare, Steven L Roach, S Whitney Barnes, Dominic Hoepfner, John R Walker, Arnab K Chatterjee, R Jeffrey Neitz, Michelle R Arkin, Case W McNamara, Jaime Ballard, Yin Lai, Yue Fu, Valentina Molteni, Vince Yeh, James H McKerrow, Richard J Glynne, Frantisek Supek

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Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia by Leopold Garnar-Wortzel, Timothy R. Bishop, Seiya Kitamura, Natalia Milosevich, Joshua N. Asiaban, Xiaoyu Zhang, Qinheng Zheng, Emily Chen, Anissa R. Ramos, Christopher J. Ackerman, Eric N. Hampton, Arnab K. Chatterjee, Travis S. Young, Mitchell V. Hull, K. Barry Sharpless, Benjamin F. Cravatt, Dennis W. Wolan, Michael A. Erb

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The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model by Rana Abdelnabi, Caroline S. Foo, Suzanne J.F. Kaptein, Xin Zhang, Thuc Nguyen Dan Do, Lana Langendries, Laura Vangeel, Judith Breuer, Juanita Pang, Rachel Williams, Valentijn Vergote, Elisabeth Heylen, Pieter Leyssen, Kai Dallmeier, Lotte Coelmont, Arnab K. Chatterjee, Raf Mols, Patrick Augustijns, Steven De Jonghe, Dirk Jochmans, Birgit Weynand, Johan Neyts

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Neratinib protects pancreatic beta cells in diabetes by Amin Ardestani, Sijia Li, Karthika Annamalai, Blaz Lupse, Shirin Geravandi, Aleksandra Dobrowolski, Shan Yu, Siying Zhu, Tyler D. Baguley, Murali Surakattula, Janina Oetjen, Lena Hauberg-Lotte, Raquel Herranz, Sushil Awal, Delsi Altenhofen, Van Nguyen-Tran, Sean Joseph, Peter G. Schultz, Arnab K. Chatterjee, Nikki Rogers, Matthew S. Tremblay, Weijun Shen, Kathrin Maedler

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Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor by Svenja M. Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P. Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K. Chatterjee, Kristen Johnson, Kaycie Morwood, Katharina Rox, Walid A. M. Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna K. H. Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F. Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann

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Drug repurposing screens identify chemical entities for the development of COVID-19 interventions by Malina A. Bakowski, Nathan Beutler, Karen C. Wolff, Melanie G. Kirkpatrick, Emily Chen, Tu-Trinh H. Nguyen, Laura Riva, Namir Shaabani, Mara Parren, James Ricketts, Anil K. Gupta, Kastin Pan, Peiting Kuo, MacKenzie Fuller, Elijah Garcia, John R. Teijaro, Linlin Yang, Debashis Sahoo, Victor Chi, Edward Huang, Natalia Vargas, Amanda J. Roberts, Soumita Das, Pradipta Ghosh, Ashley K. Woods, Sean B. Joseph, Mitchell V. Hull, Peter G. Schultz, Dennis R. Burton, Arnab K. Chatterjee, Case W. McNamara, Thomas F. Rogers

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