Evaluation of the tolerability and safety of [225Ac]Ac-PSMA-I&T in patients with metastatic prostate cancer: a phase I dose escalation study by Sui wai Ling, Astrid A. M. van der Veldt, Mark Konijnenberg, Marcel Segbers, Eline Hooijman, Frank Bruchertseifer, Alfred Morgenstern, Erik de Blois, Tessa Brabander

Get full text

Improved postprocessing of dynamic glucose-enhanced CEST MRI for imaging brain metastases at 3 T by Yulun Wu, Sophie H. A. E. Derks, Tobias C. Wood, Erik de Blois, Astrid A. M. van der Veldt, Marion Smits, Esther A. H. Warnert

Get full text

Suitability of tumor-associated antibodies as predictive biomarker for response to immune checkpoint inhibitors in patients with melanoma: a short report by Ron H J Mathijssen, Reno Debets, Arjen Joosse, Astrid A M van der Veldt, Marco W J Schreurs, Sharon Veenbergen, Karlijn de Joode, Claudia Kransse, Dian Kortleve

Get full text

Pemetrexed induced thymidylate synthase inhibition in non-small cell lung cancer patients: a pilot study with 3'-deoxy-3'-[¹⁸F]fluorothymidine positron emission tomography. by Virginie Frings, Astrid A M van der Veldt, Ronald Boellaard, Gerarda J M Herder, Elisa Giovannetti, Richard Honeywell, Godefridus J Peters, Erik Thunnissen, Otto S Hoekstra, Egbert F Smit

Get full text

Oncological healthcare providers’ perspectives on appropriate melanoma survivorship care: a qualitative focus group study by Nadia C. W. Kamminga, Marlies Wakkee, Rianne J. De Bruin, Astrid. A. M. van der Veldt, Arjen Joosse, Suzan W. I. Reeder, Peter W. Plaisier, Tamar Nijsten, Marjolein Lugtenberg

Get full text

From decision to reflection: understanding the experiences and unmet care needs of patients treated with immunotherapy for melanoma in the adjuvant or metastatic setting by Nadia C.W. Kamminga, Astrid A.M. van der Veldt, Marlies Wakkee, Fauve R. van den Berge, Lianne A.A. van der Beek, Margot C.W. Joosen, Arjen Joosse, Karlijn de Joode, Tamar E.C. Nijsten, Marjolein Lugtenberg

Get full text

Donor-derived cell-free DNA detects kidney transplant rejection during nivolumab treatment by Daan P. Hurkmans, Jeroen G. H. P. Verhoeven, Kitty de Leur, Karin Boer, Arjen Joosse, Carla C. Baan, Jan H. von der Thüsen, Ron H. N. van Schaik, Ron H. J. Mathijssen, Astrid A. M. van der Veldt, Dennis A. Hesselink

Get full text

Comprehensive characterization of circulating tumor cells and cell‐free DNA in patients with metastatic melanoma by Manouk K. Bos, Jaco Kraan, Martijn P. A. Starmans, Jean C. A. Helmijr, Noortje Verschoor, Maja J. A. De Jonge, Arjen Joosse, Astrid A. M. van derVeldt, Peter A. W. teBoekhorst, John W. M. Martens, Stefan Sleijfer, Saskia M. Wilting

Get full text

Genome‐wide aneuploidy detected by mFast‐SeqS in circulating cell‐free DNA is associated with poor response to pembrolizumab in patients with advanced urothelial cancer by Pauline A. J. Mendelaar, Debbie G. J. Robbrecht, Maud Rijnders, Ronald deWit, Vanja deWeerd, Teoman Deger, Hans M. Westgeest, Maureen J. B. Aarts, Jens Voortman, John W. M. Martens, Astrid A. M. van derVeldt, José Alberto Nakauma‐González, Saskia M. Wilting, Martijn Lolkema

Get full text

CD45RA+CCR7− CD8 T cells lacking co-stimulatory receptors demonstrate enhanced frequency in peripheral blood of NSCLC patients responding to nivolumab by Andre Kunert, Edwin A. Basak, Daan P. Hurkmans, Hayri E. Balcioglu, Yarne Klaver, Mandy van Brakel, Astrid A. M. Oostvogels, Cor H. J. Lamers, Sander Bins, Stijn L. W. Koolen, Astrid A. M. van der Veldt, Stefan Sleijfer, Ron H. J. Mathijssen, Joachim G. J. V. Aerts, Reno Debets

Get full text

Granzyme B is correlated with clinical outcome after PD-1 blockade in patients with stage IV non-small-cell lung cancer by Reno Debets, Edwin A. Basak, Daan P. Hurkmans, Sander Bins, Stijn L. W. Koolen, Astrid A. M. van der Veldt, Stefan Sleijfer, Ron H. J. Mathijssen, Joachim G. J. V. Aerts, Ron H. N. van Schaik, Cor H. van der Leest, Nina Schepers, Esther Oomen-De Hoop, Samira El Bouazzaoui

Get full text

Prospective real-world study on the pharmacokinetics of pembrolizumab in patients with solid tumors by Markus Joerger, Reno Debets, Edwin A. Basak, Daan P. Hurkmans, Cor H. van der Leest, Sebastiaan D.T. Sassen, Karlijn de Joode, Lisanne Putter, Annemarie J.M. Wijkhuijs, Birgit C.P. Koch, Marco W.J. Schreurs, Astrid A.M. van der Veldt, Joachim G.J.V. Aerts, Ron H.J. Mathijssen, Stijn L.W. Koolen

Get full text

A prospective cohort study on the pharmacokinetics of nivolumab in metastatic non-small cell lung cancer, melanoma, and renal cell cancer patients by Daan P. Hurkmans, Edwin A. Basak, Tanja van Dijk, Darlene Mercieca, Marco W. J. Schreurs, Annemarie J. M. Wijkhuijs, Sander Bins, Esther Oomen-de Hoop, Reno Debets, Markus Joerger, Arlette Odink, Astrid A. M. van der Veldt, Cor H. van der Leest, Joachim G. J. V. Aerts, Ron H. J. Mathijssen, Stijn L. W. Koolen

Get full text

Gene-expression-based T-Cell-to-Stroma Enrichment (TSE) score predicts response to immune checkpoint inhibitors in urothelial cancer by Maud Rijnders, J. Alberto Nakauma-González, Debbie G. J. Robbrecht, Alberto Gil-Jimenez, Hayri E. Balcioglu, Astrid A. M. Oostvogels, Maureen J. B. Aarts, Joost L. Boormans, Paul Hamberg, Michiel S. van der Heijden, Bernadett E. Szabados, Geert J. L. H. van Leenders, Niven Mehra, Jens Voortman, Hans M. Westgeest, Ronald de Wit, Astrid A. M. van der Veldt, Reno Debets, Martijn P. Lolkema

Get full text

mRNA-1273 vaccination induces polyfunctional memory CD4 and CD8 T cell responses in patients with solid cancers undergoing immunotherapy or/and chemotherapy by Anastasia Gangaev, Yannick van Sleen, Nicole Brandhorst, Kelly Hoefakker, Bimal Prajapati, Amrita Singh, Annemarie Boerma, Marieke van der Heiden, Sjoukje F. Oosting, Astrid A. M. van der Veldt, T. Jeroen N. Hiltermann, Corine H. GeurtsvanKessel, Anne-Marie C. Dingemans, Egbert F. Smit, Elisabeth G. E. de Vries, John B. A. G. Haanen, Pia Kvistborg, Debbie van Baarle, Debbie van Baarle

Get full text

Cemiplimab in locally advanced or metastatic cutaneous squamous cell carcinoma: prospective real-world data from the DRUG Access ProtocolResearch in context by Karlijn Verkerk, Birgit S. Geurts, Laurien J. Zeverijn, Vincent van der Noort, Henk M.W. Verheul, John B.A.G. Haanen, Astrid A.M. van der Veldt, Ferry A.L.M. Eskens, Maureen J.B. Aarts, Carla M.L. van Herpen, Mathilde Jalving, Jourik A. Gietema, Lot A. Devriese, Mariette Labots, Sahar Barjesteh van Waalwijk van Doorn-Khosrovani, Egbert F. Smit, Haiko J. Bloemendal

Get full text

Multi-omic analysis identifies hypoalbuminemia as independent biomarker of poor outcome upon PD-1 blockade in metastatic melanoma by Lindsay V. M. Leek, Jessica C. L. Notohardjo, Karlijn de Joode, Eline L. Velker, John B. A. G. Haanen, Karijn P. M. Suijkerbuijk, Maureen J. B. Aarts, Jan Willem B. de Groot, Ellen Kapiteijn, Franchette W. P. J. van den Berkmortel, Hans M. Westgeest, Tanja D. de Gruijl, Valesca P. Retel, Edwin Cuppen, Astrid A. M. van der Veldt, Mariette Labots, Emile E. Voest, Joris van de Haar, Alfons J. M. van den Eertwegh

Get full text

Correlation between Histopathological Prognostic Tumor Characteristics and [¹⁸F]FDG Uptake in Corresponding Metastases in Newly Diagnosed Metastatic Breast Cancer by Jorianne Boers, Bertha Eisses, Mieke C. Zwager, Jasper J. L. van Geel, Frederike Bensch, Erik F. J. de Vries, Geke A. P. Hospers, Andor W. J. M. Glaudemans, Adrienne H. Brouwers, Martijn A. M. den Dekker, Sjoerd G. Elias, Evelien J. M. Kuip, Carla M. L. van Herpen, Agnes Jager, Astrid A. M. van der Veldt, Daniela E. Oprea-Lager, Elisabeth G. E. de Vries, Bert van der Vegt, Willemien C. Menke-van der Houven van Oordt, Carolina P. Schröder

Get full text

Safe Stop IPI-NIVO trial: early discontinuation of nivolumab upon achieving a complete or partial response in patients with irresectable stage III or metastatic melanoma treated wi... by J. C. Janssen, B. van Dijk, K. de Joode, M. J. B. Aarts, F. W. P. J. van den Berkmortel, C. U. Blank, M. J. Boers-Sonderen, A. J. M. van den Eertwegh, J. W. B. de Groot, M. Jalving, M. J. A. de Jonge, A. Joosse, E. Kapiteijn, A. M. Kamphuis-Huismans, K. A. T. Naipal, D. Piersma, B. Rikhof, H. M. Westgeest, G. Vreugdenhil, E. Oomen-de Hoop, E. E. A. P. Mulder, Astrid A. M. van der Veldt

Get full text

Improving survival in advanced melanoma patients: a trend analysis from 2013 to 2021Research in context by Olivier J. van Not, Alfons J.M. van den Eertwegh, John B. Haanen, Christian U. Blank, Maureen J.B. Aarts, Jesper van Breeschoten, Franchette W.P.J. van den Berkmortel, Jan-Willem B. de Groot, Geke A.P. Hospers, Rawa K. Ismail, Ellen Kapiteijn, Manja Bloem, Melissa M. De Meza, Djura Piersma, Rozemarijn S. van Rijn, Marion A.M. Stevense-den Boer, Astrid A.M. van der Veldt, Gerard Vreugdenhil, Marye J. Boers-Sonderen, Willeke A.M. Blokx, Michel W.J.M. Wouters, Karijn P.M. Suijkerbuijk

Get full text