Evaluating diagnostic tests during outbreaks: challenges and lessons learnt from COVID-19 by Camille Escadafal, Devy M Emperador, Daniel G Bausch, Aurélien Macé, Rossella Baldan, Margaretha De Vos, Ryan Jose Ruiz, Alltalents T Murahwa, Aurélia Vessière, Jilian A Sacks

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Diagnostic Performance and Usability of the Genedrive^® HCV ID Kit in Two Decentralized Settings in Cameroon and Georgia by Francois M. J. Lamoury, Richard Njouom, Marie Amougou-Atsama, Euloge Yiagnigni Mfopou, Nino Berishvili, Manana Sologashvili, Emmanuel Fajardo, Agnes Malobela, Aurélien Macé, Maxwell Chirehwa, Maia Alkhazashvili, Elena Ivanova Reipold

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Whole-genome and targeted sequencing of drug-resistant Mycobacterium tuberculosis on the iSeq100 and MiSeq: A performance, ease-of-use, and cost evaluation. by Rebecca E Colman, Aurélien Mace, Marva Seifert, Jonathan Hetzel, Haifa Mshaiel, Anita Suresh, Darrin Lemmer, David M Engelthaler, Donald G Catanzaro, Amanda G Young, Claudia M Denkinger, Timothy C Rodwell

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Bacterial versus non-bacterial infections: a methodology to support use-case-driven product development of diagnostics by Camille Escadafal, Sabine Dittrich, Birkneh Tilahun Tadesse, B Leticia Fernandez-Carballo, Steffen Geis, A M Siqueira, Selidji T Agnandji, Techalew Shimelis, Marguerite Massinga Loembé, Victoria Harris, Aurélien Macé, Stefano Ongarello, William Rodriguez

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Accuracy of novel antigen rapid diagnostics for SARS-CoV-2: A living systematic review and meta-analysis. by Lukas E Brümmer, Stephan Katzenschlager, Mary Gaeddert, Christian Erdmann, Stephani Schmitz, Marc Bota, Maurizio Grilli, Jan Larmann, Markus A Weigand, Nira R Pollock, Aurélien Macé, Sergio Carmona, Stefano Ongarello, Jilian A Sacks, Claudia M Denkinger

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Diagnostic accuracy of a novel tuberculosis point-of-care urine lipoarabinomannan assay for people living with HIV: A meta-analysis of individual in- and outpatient data. by Tobias Broger, Mark P Nicol, Rita Székely, Stephanie Bjerrum, Bianca Sossen, Charlotte Schutz, Japheth A Opintan, Isik S Johansen, Satoshi Mitarai, Kinuyo Chikamatsu, Andrew D Kerkhoff, Aurélien Macé, Stefano Ongarello, Graeme Meintjes, Claudia M Denkinger, Samuel G Schumacher

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Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2: An updated systematic review and meta-analysis with meta-regression analyzing influencing factors. by Lukas E Brümmer, Stephan Katzenschlager, Sean McGrath, Stephani Schmitz, Mary Gaeddert, Christian Erdmann, Marc Bota, Maurizio Grilli, Jan Larmann, Markus A Weigand, Nira R Pollock, Aurélien Macé, Berra Erkosar, Sergio Carmona, Jilian A Sacks, Stefano Ongarello, Claudia M Denkinger

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Comparing SARS-CoV-2 antigen-detection rapid diagnostic tests for COVID-19 self-testing/self-sampling with molecular and professional-use tests: a systematic review and meta-analys... by Stephan Katzenschlager, Lukas E. Brümmer, Stephani Schmitz, Hannah Tolle, Katharina Manten, Mary Gaeddert, Christian Erdmann, Andreas Lindner, Frank Tobian, Maurizio Grilli, Nira R. Pollock, Aurélien Macé, Berra Erkosar, Sergio Carmona, Stefano Ongarello, Cheryl C. Johnson, Jilian A. Sacks, Claudia M. Denkinger, Seda Yerlikaya

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Clinical accuracy of instrument-based SARS-CoV-2 antigen diagnostic tests: a systematic review and meta-analysis by Katharina Manten, Stephan Katzenschlager, Lukas E. Brümmer, Stephani Schmitz, Mary Gaeddert, Christian Erdmann, Maurizio Grilli, Nira R. Pollock, Aurélien Macé, Berra Erkosar, Sergio Carmona, Stefano Ongarello, Cheryl C. Johnson, Jilian A. Sacks, Verena Faehling, Linus Bornemann, Markus A. Weigand, Claudia M. Denkinger, Seda Yerlikaya

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Prospective multicentre accuracy evaluation of the FUJIFILM SILVAMP TB LAM test for the diagnosis of tuberculosis in people living with HIV demonstrates lot-to-lot variability. by Rita Székely, Bianca Sossen, Madalo Mukoka, Monde Muyoyeta, Elizabeth Nakabugo, Jerry Hella, Hung Van Nguyen, Sasiwimol Ubolyam, Kinuyo Chikamatsu, Aurélien Macé, Marcia Vermeulen, Chad M Centner, Sarah Nyangu, Nsala Sanjase, Mohamed Sasamalo, Huong Thi Dinh, The Anh Ngo, Weerawat Manosuthi, Supunnee Jirajariyavej, Satoshi Mitarai, Nhung Viet Nguyen, Anchalee Avihingsanon, Klaus Reither, Lydia Nakiyingi, Andrew D Kerkhoff, Peter MacPherson, Graeme Meintjes, Claudia M Denkinger, Morten Ruhwald, FujiLAM Study Consortium

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Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels by Adrienne Tin, Yong Li, Jennifer A. Brody, Teresa Nutile, Audrey Y. Chu, Jennifer E. Huffman, Qiong Yang, Ming-Huei Chen, Cassianne Robinson-Cohen, Aurélien Macé, Jun Liu, Ayşe Demirkan, Rossella Sorice, Sanaz Sedaghat, Melody Swen, Bing Yu, Sahar Ghasemi, Alexanda Teumer, Peter Vollenweider, Marina Ciullo, Meng Li, André G. Uitterlinden, Robert Kraaij, Najaf Amin, Jeroen van Rooij, Zoltán Kutalik, Abbas Dehghan, Barbara McKnight, Cornelia M. van Duijn, Alanna Morrison, Bruce M. Psaty, Eric Boerwinkle, Caroline S. Fox, Owen M. Woodward, Anna Köttgen

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Cross-sectional evaluation of host biomarkers for guiding antibiotic use in bacterial and non-bacterial acute febrile illness in low- and middle-income tropical settings by Camille Escadafal, Patrícia Brasil, Louis Banda, Sabine Dittrich, Sunil Pokharel, B Leticia Fernandez-Carballo, Barbara Di Camillo, Martina Vettoretti, Steffen Geis, Victoria Harris, Aurélien Macé, Stefano Ongarello, Sue J Lee, Selidji Todagbe Agnandji, Braulia C Caetano, Marilda M Siqueira, Jose Moreira, Jullita Kenala Malava, Paulin N Essone, Ayodele Alabi, Meike Jakobi, Nicole Schneiderhan-Marra, Michele Atzeni, Andre M Siqueira, Anita L Kabwende, Juste Christin Bie Ondo, Marguerite Massinga-Loembe, Aline da Rocha Matos, Ana Maria Bispo de Filippis, Érica Aparecida dos Santos Ribeiro da Silva, Maria Cristina S Lourenço, Julia Häring, Anna Günther, Christine Hoogland

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Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index. by Clive J Hoggart, Giulia Venturini, Massimo Mangino, Felicia Gomez, Giulia Ascari, Jing Hua Zhao, Alexander Teumer, Thomas W Winkler, Natalia Tšernikova, Jian'an Luan, Evelin Mihailov, Georg B Ehret, Weihua Zhang, David Lamparter, Tõnu Esko, Aurelien Macé, Sina Rüeger, Pierre-Yves Bochud, Matteo Barcella, Yves Dauvilliers, Beben Benyamin, David M Evans, Caroline Hayward, Mary F Lopez, Lude Franke, Alessia Russo, Iris M Heid, Erika Salvi, Sailaja Vendantam, Dan E Arking, Eric Boerwinkle, John C Chambers, Giovanni Fiorito, Harald Grallert, Simonetta Guarrera, Georg Homuth, Jennifer E Huffman, David Porteous, Generation Scotland Consortium, LifeLines Cohort study, GIANT Consortium, Darius Moradpour, Alex Iranzo, Johannes Hebebrand, John P Kemp, Gert J Lammers, Vincent Aubert, Markus H Heim, Nicholas G Martin, Grant W Montgomery, Rosa Peraita-Adrados, Joan Santamaria, Francesco Negro, Carsten O Schmidt, Robert A Scott, Tim D Spector, Konstantin Strauch, Henry Völzke, Nicholas J Wareham, Wei Yuan, Jordana T Bell, Aravinda Chakravarti, Jaspal S Kooner, Annette Peters, Giuseppe Matullo, Henri Wallaschofski, John B Whitfield, Fred Paccaud, Peter Vollenweider, Sven Bergmann, Jacques S Beckmann, Mehdi Tafti, Nicholas D Hastie, Daniele Cusi, Murielle Bochud, Timothy M Frayling, Andres Metspalu, Marjo-Riitta Jarvelin, André Scherag, George Davey Smith, Ingrid B Borecki, Valentin Rousson, Joel N Hirschhorn, Carlo Rivolta, Ruth J F Loos, Zoltán Kutalik

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CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits by Aurélien Macé, Marcus A. Tuke, Patrick Deelen, Kati Kristiansson, Hannele Mattsson, Margit Nõukas, Yadav Sapkota, Ursula Schick, Eleonora Porcu, Sina Rüeger, Aaron F. McDaid, David Porteous, Thomas W. Winkler, Erika Salvi, Nick Shrine, Xueping Liu, Wei Q. Ang, Weihua Zhang, Mary F. Feitosa, Cristina Venturini, Peter J. van der Most, Anders Rosengren, Andrew R. Wood, Robin N. Beaumont, Samuel E. Jones, Katherine S. Ruth, Hanieh Yaghootkar, Jessica Tyrrell, Aki S. Havulinna, Harmen Boers, Reedik Mägi, Jennifer Kriebel, Martina Müller-Nurasyid, Markus Perola, Markku Nieminen, Marja-Liisa Lokki, Mika Kähönen, Jorma S. Viikari, Frank Geller, Jari Lahti, Aarno Palotie, Päivikki Koponen, Annamari Lundqvist, Harri Rissanen, Erwin P. Bottinger, Saima Afaq, Mary K. Wojczynski, Petra Lenzini, Ilja M. Nolte, Thomas Sparsø, Nicole Schupf, Kaare Christensen, Thomas T. Perls, Anne B. Newman, Thomas Werge, Harold Snieder, Timothy D. Spector, John C. Chambers, Seppo Koskinen, Mads Melbye, Olli T. Raitakari, Terho Lehtimäki, Martin D. Tobin, Louise V. Wain, Juha Sinisalo, Annette Peters, Thomas Meitinger, Nicholas G. Martin, Naomi R. Wray, Grant W. Montgomery, Sarah E. Medland, Morris A. Swertz, Erkki Vartiainen, Katja Borodulin, Satu Männistö, Anna Murray, Murielle Bochud, Sébastien Jacquemont, Fernando Rivadeneira, Thomas F. Hansen, Albertine J. Oldehinkel, Massimo Mangino, Michael A. Province, Panos Deloukas, Jaspal S. Kooner, Rachel M. Freathy, Craig Pennell, Bjarke Feenstra, David P. Strachan, Guillaume Lettre, Joel Hirschhorn, Daniele Cusi, Iris M. Heid, Caroline Hayward, Katrin Männik, Jacques S. Beckmann, Ruth J. F. Loos, Dale R. Nyholt, Andres Metspalu, Johan G. Eriksson, Michael N. Weedon, Veikko Salomaa, Lude Franke, Alexandre Reymond, Timothy M. Frayling, Zoltán Kutalik

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Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. by Conall M O'Seaghdha, Hongsheng Wu, Qiong Yang, Karen Kapur, Idris Guessous, Annie Mercier Zuber, Anna Köttgen, Candice Stoudmann, Alexander Teumer, Zoltán Kutalik, Massimo Mangino, Abbas Dehghan, Weihua Zhang, Gudny Eiriksdottir, Guo Li, Toshiko Tanaka, Laura Portas, Lorna M Lopez, Caroline Hayward, Kurt Lohman, Koichi Matsuda, Sandosh Padmanabhan, Dmitri Firsov, Rossella Sorice, Sheila Ulivi, A Catharina Brockhaus, Marcus E Kleber, Anubha Mahajan, Florian D Ernst, Vilmundur Gudnason, Lenore J Launer, Aurelien Mace, Eric Boerwinckle, Dan E Arking, Chizu Tanikawa, Yusuke Nakamura, Morris J Brown, Jean-Michel Gaspoz, Jean-Marc Theler, David S Siscovick, Bruce M Psaty, Sven Bergmann, Peter Vollenweider, Veronique Vitart, Alan F Wright, Tatijana Zemunik, Mladen Boban, Ivana Kolcic, Pau Navarro, Edward M Brown, Karol Estrada, Jingzhong Ding, Tamara B Harris, Stefania Bandinelli, Dena Hernandez, Andrew B Singleton, Giorgia Girotto, Daniela Ruggiero, Adamo Pio d'Adamo, Antonietta Robino, Thomas Meitinger, Christa Meisinger, Gail Davies, John M Starr, John C Chambers, Bernhard O Boehm, Bernhard R Winkelmann, Jie Huang, Federico Murgia, Sarah H Wild, Harry Campbell, Andrew P Morris, Oscar H Franco, Albert Hofman, Andre G Uitterlinden, Fernando Rivadeneira, Uwe Völker, Anke Hannemann, Reiner Biffar, Wolfgang Hoffmann, So-Youn Shin, Pierre Lescuyer, Hughes Henry, Claudia Schurmann, SUNLIGHT Consortium, GEFOS Consortium, Patricia B Munroe, Paolo Gasparini, Nicola Pirastu, Marina Ciullo, Christian Gieger, Winfried März, Lars Lind, Tim D Spector, Albert V Smith, Igor Rudan, James F Wilson, Ozren Polasek, Ian J Deary, Mario Pirastu, Luigi Ferrucci, Yongmei Liu, Bryan Kestenbaum, Jaspal S Kooner, Jacqueline C M Witteman, Matthias Nauck, W H Linda Kao, Henri Wallaschofski, Olivier Bonny, Caroline S Fox, Murielle Bochud

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