SGC-AAK1-1: a chemical probe targeting AAK1 and BMP2K by Wells, C, Couñago, R, Limas, J, Almeida, T, Cook, J, Drewry, D, Elkins, J, Gileadi, O, Kapadia, N, Lorente-Macias, A, Pickett, J, Riemen, A, Ruela-De-Sousa, R, Willson, T, Zhang, C, Zuercher, W, Zutshi, R, Axtman, A

Progress towards a public chemogenomic set for protein kinases and a call for contributions. by Drewry, D, Wells, C, Andrews, D, Angell, R, Al-Ali, H, Axtman, A, Capuzzi, S, Elkins, J, Ettmayer, P, Frederiksen, M, Gileadi, O, Gray, N, Hooper, A, Knapp, S, Laufer, S, Luecking, U, Michaelides, M, Müller, S, Muratov, E, Denny, R, Saikatendu, K, Treiber, D, Zuercher, W, Willson, T

WNT activates the AAK1 kinase to promote clathrin-mediated endocytosis of LRP6 and establish a negative feedback loop by Agajanian, M, Walker, M, Axtman, A, Ruela-De-Sousa, R, Serafin, D, Rabinowitz, A, Graham, D, Ryan, M, Tamir, T, Nakamichi, Y, Gammons, M, Bennett, J, Couñago, R, Drewry, D, Elkins, J, Gileadi, C, Gileadi, O, Godoi, P, Kapadia, N, Müller, S, Santiago, A, Sorrell, F, Wells, C, Fedorov, O, Willson, T, Zuercher, W, Major, M