Quantification of Plasmodium knowlesi versus Plasmodium falciparum in the rhesus liver: implications for malaria vaccine studies in rhesus models by Melanie J. Shears, Annette M. Seilie, B. Kim Lee Sim, Stephen L. Hoffman, Sean C. Murphy

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Transcriptome profiling reveals functional variation in Plasmodium falciparum parasites from controlled human malaria infection studiesResearch in context by Regina Hoo, Ellen Bruske, Sandra Dimonte, Lei Zhu, Benjamin Mordmüller, B. Kim Lee Sim, Peter G. Kremsner, Stephen L. Hoffman, Zbynek Bozdech, Matthias Frank, Peter R. Preiser

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Is Saglin a mosquito salivary gland receptor for Plasmodium falciparum? by David A. O’Brochta, Robert Alford, Robert Harrell, Channa Aluvihare, Abraham G. Eappen, Tao Li, Sumana Chakravarty, B. Kim Lee Sim, Stephen L. Hoffman, Peter F. Billingsley

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Plasmodium falciparum malaria challenge by the bite of aseptic Anopheles stephensi mosquitoes: results of a randomized infectivity trial. by Kirsten E Lyke, Matthew Laurens, Matthew Adams, Peter F Billingsley, Adam Richman, Mark Loyevsky, Sumana Chakravarty, Christopher V Plowe, B Kim Lee Sim, Robert Edelman, Stephen L Hoffman

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Knockout of Anopheles stephensi immune gene LRIM1 by CRISPR-Cas9 reveals its unexpected role in reproduction and vector competence. by Ehud Inbar, Abraham G Eappen, Robert T Alford, William Reid, Robert A Harrell, Maryam Hosseini, Sumana Chakravarty, Tao Li, B Kim Lee Sim, Peter F Billingsley, Stephen L Hoffman

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Delineation of stage specific expression of Plasmodium falciparum EBA-175 by biologically functional region II monoclonal antibodies. by B Kim Lee Sim, David L Narum, Rana Chattopadhyay, Adriana Ahumada, J David Haynes, Steven R Fuhrmann, Jennifer N Wingard, Hong Liang, J Kathleen Moch, Stephen L Hoffman

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Sex-Specific Differences in Cytokine Induction by the Glycolipid Adjuvant 7DW8-5 in Mice by Felicia N. Watson, Caroline J. Duncombe, Anya C. Kalata, Ethan Conrad, Sumana Chakravarty, B. Kim Lee Sim, Stephen L. Hoffman, Moriya Tsuji, Melanie J. Shears, Sean C. Murphy

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Whole blood transcriptome changes following controlled human malaria infection in malaria pre-exposed volunteers correlate with parasite prepatent period. by Julian Rothen, Carl Murie, Jason Carnes, Atashi Anupama, Salim Abdulla, Mwajuma Chemba, Maxmillian Mpina, Marcel Tanner, B Kim Lee Sim, Stephen L Hoffman, Raphael Gottardo, Claudia Daubenberger, Ken Stuart

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Transient knockdown of Anopheles stephensi LRIM1 using RNAi increases Plasmodium falciparum sporozoite salivary gland infections by Peter F. Billingsley, Kasim I. George, Abraham G. Eappen, Robert A. Harrell, Robert Alford, Tao Li, Sumana Chakravarty, B. Kim Lee Sim, Stephen L. Hoffman, David A. O’Brochta

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A replication competent Plasmodium falciparum parasite completely attenuated by dual gene deletion by Debashree Goswami, Hardik Patel, William Betz, Janna Armstrong, Nelly Camargo, Asha Patil, Sumana Chakravarty, Sean C Murphy, B Kim Lee Sim, Ashley M Vaughan, Stephen L Hoffman, Stefan HI Kappe

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Mosquito Passage Dramatically Changes var Gene Expression in Controlled Human Plasmodium falciparum Infections. by Anna Bachmann, Michaela Petter, Ralf Krumkamp, Meral Esen, Jana Held, Judith A M Scholz, Tao Li, B Kim Lee Sim, Stephen L Hoffman, Peter G Kremsner, Benjamin Mordmüller, Michael F Duffy, Egbert Tannich

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A First for Human Vaccinology: GMP Compliant Radiation Attenuation of Plasmodium falciparum Sporozoites for Production of a Vaccine Against Malaria by Eric R. James, Steve Matheny, James Overby, B. Kim Lee Sim, Abraham G. Eappen, Tao Li, Ming Lin Li, Thomas L. Richie, Sumana Chakravarty, Anusha Gunasekera, Tooba Murshedkar, Peter F. Billingsley, Stephen L. Hoffman

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Successful human infection with P. falciparum using three aseptic Anopheles stephensi mosquitoes: a new model for controlled human malaria infection. by Matthew B Laurens, Peter Billingsley, Adam Richman, Abraham G Eappen, Matthew Adams, Tao Li, Sumana Chakravarty, Anusha Gunasekera, Christopher G Jacob, B Kim Lee Sim, Robert Edelman, Christopher V Plowe, Stephen L Hoffman, Kirsten E Lyke

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Plasmodium 18S rRNA of intravenously administered sporozoites does not persist in peripheral blood by Sean C. Murphy, Andrew S. Ishizuka, Zachary P. Billman, Tayla M. Olsen, Annette M. Seilie, Ming Chang, Nahum Smith, Vorada Chuenchob, Sumana Chakravarty, B. Kim Lee Sim, Stefan H. I. Kappe, Stephen L. Hoffman, Robert A. Seder

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Proteome-wide analysis of a malaria vaccine study reveals personalized humoral immune profiles in Tanzanian adults by Flavia Camponovo, Joseph J Campo, Timothy Q Le, Amit Oberai, Christopher Hung, Jozelyn V Pablo, Andy A Teng, Xiaowu Liang, B Kim Lee Sim, Said Jongo, Salim Abdulla, Marcel Tanner, Stephen L Hoffman, Claudia Daubenberger, Melissa A Penny

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Controlled human malaria infection with Plasmodium falciparum demonstrates impact of naturally acquired immunity on virulence gene expression. by Anna Bachmann, Ellen Bruske, Ralf Krumkamp, Louise Turner, J Stephan Wichers, Michaela Petter, Jana Held, Michael F Duffy, B Kim Lee Sim, Stephen L Hoffman, Peter G Kremsner, Bertrand Lell, Thomas Lavstsen, Matthias Frank, Benjamin Mordmüller, Egbert Tannich

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PfSPZ-CVac efficacy against malaria increases from 0% to 75% when administered in the absence of erythrocyte stage parasitemia: A randomized, placebo-controlled trial with controll... by Sean C Murphy, Gregory A Deye, B Kim Lee Sim, Shirley Galbiati, Jessie K Kennedy, Kristen W Cohen, Sumana Chakravarty, Natasha Kc, Yonas Abebe, Eric R James, James G Kublin, Stephen L Hoffman, Thomas L Richie, Lisa A Jackson

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Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa by Joana C. Silva, Ankit Dwivedi, Kara A. Moser, Mahamadou S. Sissoko, Judith E. Epstein, Sara A. Healy, Kirsten E. Lyke, Benjamin Mordmüller, Peter G. Kremsner, Patrick E. Duffy, Tooba Murshedkar, B. Kim Lee Sim, Thomas L. Richie, Stephen L. Hoffman

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Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria by Felicia N. Watson, Melanie J. Shears, Anya C. Kalata, Caroline J. Duncombe, A. Mariko Seilie, Chris Chavtur, Ethan Conrad, Irene Cruz Talavera, Andrew Raappana, D. Noah Sather, Sumana Chakravarty, B. Kim Lee Sim, Stephen L. Hoffman, Moriya Tsuji, Sean C. Murphy

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Protection against inhalation anthrax by immunization with Salmonella enterica serovar Typhi Ty21a stably producing protective antigen of Bacillus anthracis by B. Kim Lee Sim, Minglin Li, Manuel Osorio, Yun Wu, Tint T. Wai, Johnny W. Peterson, Eric R. James, Sumana Chakravarty, Lixin Gao, Rui Xu, Natasha KC, Richard E. Stafford, William S. Lawrence, Linsey A. Yeager, Jennifer E. Peel, Satheesh K. Sivasubramani, Ashok K. Chopra, Svetlana Filippova, Stephen L. Hoffman

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