Computational detection of off-target effects of CRISPR/Cas9-associated gRNAs by W. Dampier, Ch.H. Chung, M.R. Nonnemacher, B. Wigdahl

Get full text

Broad-spectrum gRNAs abolish HIV-1 LTR-mediated transcription in cells that receive CRISPR/Cas9 therapy by B. Wigdahl, A. Allen, S. Worell, G. Nwaozo, R. Madrid, W. Dampier, M. Nonnemacher

Get full text

Utilizing the binding capacity of CRISPR/Cas9 to target the HIV-1 quasispecies by M. Nonnemacher, W. Dampier, M. Desimone, V. Pirrone, K. Kercher, S. Passic, J. Williams, B. Wigdahl

Get full text

PP 1.43 – 00206 Evaluating integrated HIV-1 quasispecies using Near Full Length sequencing in ART-suppressed individuals in the Drexel CARES Cohort by M. Collins, D. De Souza, W. Dampier, C. Spector, V. Pirrone, S. Passic, K. Malone, S. Tillman, B. Wigdahl, M. Nonnemacher

Get full text

PP 6.5 – 00205 Utilization of high-throughput assays and deep-learning for selection of CRISPR/Cas9-gRNA pairs used in an HIV-1 cure strategy by R. Berman, W. Dampier, A. Atkins, A. Allen, V. Pirrone, S. Passic, A. Ahmed, Z. Szep, M. Nonnemacher, B. Wigdahl

Get full text

CRISPR/Cas9 editing of HIV-1 transcription factor binding sites on the 5’ long terminal repeats to permanently inactivate latent provirus by B. Wigdahl, C.-H. Chung, A.G. Allen, A.J. Atkins, R. Costello, N.T. Sullivan, M.R. Nonnemacher, W.N. Dampier

Get full text

Mild cognitive impairment in a clinically latent HIV-1 patient population by K.N. Devlin, T. Giovannetti, W. Dampier, V. Pirrone, M.R. Nonnemacher, E. Schell, C. Lamberson, J.R. Kurczewski, J.M. Jacobson, D.J. Libon, B. Wigdahl

Get full text

Genetic variation continues to occur in well-controlled HIV-1-infected patients by W. Dampier, M.R. Nonnemacher, J. Chang Mell, J. Earl, V. Pirrone, B. Aiamkitsumrit, W. Zhong, K. Kercher, S. Passic, J.W. Williams, J.M. Jacobson, B. Wigdahl

Get full text

Designing broad-spectrum gRNAs to target the HIV-1 LTR with CRISPR/cas9-based therapeutic strategies by A. Allen, N.T. Sullivan, W. Dampier, C.H. Chung, A. Atkins, G. Homan, V. Pirrone, S. Passic, J. Williams, Z. Szep, J.M. Jacobson, M.R. Nonnemacher, B. Wigdahl

Get full text

SNPs within the HIV-1 LTR associate with increased virus persistence by N.T. Sullivan, M.R. Nonnemacher, V. Pirrone, R. Feng, B. Moldover, W. Dampier, S. Passic, J. Williams, B. Aiamkitsumrit, W. Zhong, B. Blakey, S. Shah, J.M. Jacobson, B. Wigdahl

Get full text

Examining functional alterations of HIV-1 Tat variants associated with neurocognitively impaired patients in the Drexel Medicine CARES Cohort by M.R. Nonnemacher, A.R. Mele, K.M. King, G. Antell, W. Dampier, R. Tata, V. Pirrone, J. Williams, G. Homan, S. Passic, K. Kercher, W. Zhong, Z. Szep, J. Jacobson, B. Wigdahl, S. Kortagere

Get full text