Impact force measurement in Shirodhara Por Swathika Meenraj, Lakshmana Rao Chebolu, Balasubramanian Venkatesh

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An evaluation of factors that may influence clinicians' decisions not to enroll eligible patients into randomized trials in critical care. Por Mahesh Ramanan, Laurent Billot, Dorrilyn Rajbhandari, John Myburgh, Balasubramanian Venkatesh

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Does asymmetry in patient recruitment in large critical care trials follow the Pareto principle? Por Mahesh Ramanan, Laurent Billot, Dorrilyn Rajbhandari, John Myburgh, Simon Finfer, Rinaldo Bellomo, Balasubramanian Venkatesh

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Impact of 1-hour and 3-hour sepsis time bundles on antibiotic use in emergency departments in Queensland, Australia: a before-and-after cohort study Por Paul Lane, Kristen Gibbons, Michael Rice, Balasubramanian Venkatesh, Donna Mason, Kathryn Wilks, Robert Seaton, Lyndell Redpath, Endrias Ergetu

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Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: A before and after cohort study Por Balasubramanian Venkatesh, Luregn Schlapbach, Donna Mason, Kathryn Wilks, Robert Seaton, Paula Lister, Adam Irwin, Paul Lane, Lyndell Redpath, Kristen Gibbons, Endrias Ergetu, Michael Rice

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The impact of demonetisation on the utilisation of hospital services, patient outcomes and finances: a multicentre observational study from India Por Anand Zachariah, Bijesh Yadav, Lakshmanan Jeyaseelan, Tarun K George, John Victor Peter, Shalom Patole, Roshine Mary Koshy, Prabhu Joseph, Balasubramanian P, Aravindan Nair, Krupa George, Georgi Abraham, Balasubramanian Venkatesh

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Hydroxychloroquine plus personal protective equipment versus standard personal protective equipment alone for the prevention of COVID-19 infections among frontline healthcare worke... Por Bharath Kumar Tirupakuzhi Vijayaraghavan, Vivekanand Jha, Dorrilyn Rajbhandari, Sheila Nainan Myatra, Oommen John, Arpita Ghosh, Abhinav Bassi, Sumaiya Arfin, Mallikarjuna Kunigari, Rohina Joshi, Lachlan Donaldson, Naomi Hammond, Balasubramanian Venkatesh, the HOPE investigators

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Effects of low-dose hydrocortisone and hydrocortisone plus fludrocortisone in adults with septic shock: a protocol for a systematic review and meta-analysis of individual participa... Por Yaseen Arabi, Sylvie Chevret, Laurent Billot, Anthony Gordon, Didier Keh, Romain Pirracchio, Balasubramanian Venkatesh, Djillali Annane, Andre Waschka, Jeremy Cohen, Simon Finfer, Naomi Hammond, John Myburgh, Anthony Delaney, Pierre Edouard Bollaert, Josef Briegel, Ling Liu, G Umberto, Liliana Mirea, L Charles, Nejla Tilouche, Surat Tongyoo, Ruiqiang Zheng

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ASCOT ADAPT study of COVID-19 therapeutics in hospitalised patients: an international multicentre adaptive platform trial Por Justin T. Denholm, Balasubramanian Venkatesh, Joshua Davis, Asha C. Bowen, Naomi E. Hammond, Vivekanand Jha, Grace McPhee, Zoe McQuilten, Matthew V. N. O’Sullivan, David Paterson, David Price, Megan Rees, Jason Roberts, Mark Jones, James Totterdell, Thomas Snelling, Nanette Trask, Susan Morpeth, Steven YC Tong, on behalf of the ASCOT ADAPT investigators

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A Genome-Wide Association Study of Serum Metabolite Profiles in Septic Shock Patients Por Emily R. Daubney, BE/BSc, Shannon D’Urso, BAdvSc (Hons), Gabriel Cuellar-Partida, PhD, Dorrilyn Rajbhandari, RN, Elizabeth Peach, MS, Erika de Guzman, BBSc, Colin McArthur, MD, Andrew Rhodes, MD, Jason Meyer, RN, Simon Finfer, MD, John Myburgh, MD, PhD, Jeremy Cohen, MD, PhD, Horst Joachim Schirra, PhD, Balasubramanian Venkatesh, MD, David M. Evans, PhD

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REVISE: Re-Evaluating the Inhibition of Stress Erosions in the ICU: a randomised trial protocol Por Lehana Thabane, Gordon Guyatt, Diane Heels-Ansdell, Deborah J Cook, Yaseen Arabi, John Muscedere, Paul Young, Feng Xie, François Lauzier, Laurent Billot, Waleed Alhazzani, Marlies Ostermann, Shane English, Daniel Johnson, John C Marshall, Nicole Zytaruk, Balasubramanian Venkatesh, Simon Finfer, John Myburgh, R Hall, Mobeen Iqbal, Abdulrahman A Al-Fares, Gilmar Reis, Alexis Poole, Adam M Deane, Marianne J Chapman, Dorrilyn Rajbhandari, Naomi E Hammond, Serena Knowles, Miranda Hardie, Lois Saunders

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Corticosteroid therapy for critically ill patients with COVID-19: A structured summary of a study protocol for a prospective meta-analysis of randomized trials Por Jonathan A. C. Sterne, Janet Diaz, Jesús Villar, Srinivas Murthy, Arthur S. Slutsky, Anders Perner, Peter Jüni, Derek C. Angus, Djillali Annane, Luciano Cesar Pontes Azevedo, Bin Du, Pierre-Francois Dequin, Anthony C. Gordon, Cameron Green, Julian P. T. Higgins, Peter Horby, Martin J. Landray, Giuseppe Lapadula, Amelie Le Gouge, Marie Leclerc, Jelena Savović, Bruno Tomazini, Balasubramanian Venkatesh, Steve Webb, John C. Marshall, for the WHO COVID-19 Clinical Management and Characterization Working Group

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Transparent reporting of adaptive clinical trials using concurrently randomised cohorts Por Mark Jones, David Price, Jason Roberts, Joseph John, Tim Spelman, Thomas L Snelling, Vivekanand Jha, Steven Y C Tong, David Paterson, Balasubramanian Venkatesh, Naomi Hammond, James McFadyen, Robert Medcalf, Huyen Tran, Asha Bowen, Sanjeev Chunilal, Megan Rees, Joshua Davis, Justin Denholm, Susan Morpeth, Ian C Marschner, James McGree, James A Totterdell, Robert K Mahar, Bhupendra Basnet, Grace McPhee, Zoe McQuilten, Matthew O’Sullivan, Nanette Trask, Jennifer Curnow, Eileen Merriman, Todd Cooper, Julie Marsh

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Hydroxychloroquine plus personal protective equipment versus personal protective equipment alone for the prevention of laboratory-confirmed COVID-19 infections among healthcare wor... Por Rohina Joshi, Sudha Vidyasagar, Niveditha Devasenapathy, Rinaldo Bellomo, Vivekanand Jha, Chirag Patel, Vijay Kumar, Lachlan Donaldson, Oommen John, Balasubramanian Venkatesh, Michael John, Naomi Hammond, Jeyaraj Pandian, Ashwani Kumar, Arpita Ghosh, S Radhakrishnan, Rajib Paul, Bharath Kumar Tirupakuzhi Vijayaraghavan, Dorrilyn Rajbhandari, Sheila Nainan Myatra, Amritendu Bhattacharya, Sumaiya Arfin, Abhinav Bassi, Lachlan Hugh Donaldson, Naomi E Hammond, Mallikarjuna Kunigari, Cynthia Amrutha, Syed Haider Mehdi Husaini, Subir Ghosh, Santosh Kumar Nag, Hari Krishnan Selvaraj, Viny Kantroo, Kamal D Shah, Sheila Myatra, Amritendu Battacharya, Pavan Kumar Vecham, Evangeline Elvira, Gomathi Parthasarathy, Archana Ragunathan, Gnanavel Rajendra Kunjurao, Pavithra Sampath Kumar, Hilda Nirmala Kumari, Jayanthi Swaminathan, Murshid Cheriyeri Peediyekkal, Arun Chander Yadav, Aarthi Venkatramanan, Cynthia Amrutha Sukumar, Dharini Prasad, Krishnanda Nayak, Ravindra Prabhu, Rohini Bilagi, Akash Bhange, Bhumika Patel, Ekta Ramchandani, Jinesh Patel, Krupa Gandhi, N Prathyusha, Rayshma Rao Bonshlay Lakshmanan, S Hari Krishnan, Abhishek George Mehta, Mousumi Pradhan, Syed Haider Mehdi Husaini, Shahid Ali Siddique, Naved-ur Rahman, Mohammad Jamalludeen, Mounika Amarneni, Suresh Sankar, Vidya Rajesh Joshi, Alka Yadav, Nikhil Modi, Rinku Dahiya, Serena Knowles, Nikita Bathla, Fatima Butt

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Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department Por Amanda Harley, MN, Paula Lister, PhD, Patricia Gilholm, PhD, Michael Rice, MN, Bala Venkatesh, MD, Amy N.B. Johnston, PhD, Debbie Massey, PhD, Adam Irwin, PhD, Kristen Gibbons, PhD, Luregn J. Schlapbach, PhD, on behalf of the Queensland Statewide Sepsis Collaborative, Luregn Schlapbach, Amanda Harley, Adam Irwin, Nicolette Graham, Fiona Thomson, Kieran Owen, Kirsten Garrish, Emma Sampson, Debbie Long, Shane George, Keith Grimwood, Christa Bell, Bethany Semple, Claire Adams, Josea Brown, Louise Maloney, Paula Lister, Scott Schofield, Clare Thomas, Liam Dejong, Esther Bently, Lambros Halkidis, Cheryl Bird, Matthew Smith, Pia Alexander, Laura Davidson-West, Titiosibina Ebenezer Adegbija, Alice Brandt, Bree Walker, Andrea McLucas, Adam Philip Michael, Yulia Sugeng, Samantha Hoole, Candice Bauer, John Sutherland, Douglas Gordon Thomas, David Van der Walt, Jessica Hulme, Kerrie Burke, Helena Cooney, Doug Morel, Louise O’Riordan, Samantha Fairless, Megan Bool, Nandini Choudary, Shalini Arora, Ben Lawton, Jo Farrell, Penelope Prasad, Rudesh Prasad, Laura O’Connor, Timothy Butters, Peter Kennedy, Hanh Pham, Maya Aoude, Sara Blundell, Natasha Willmett, Louise McGrath, Karen Smith, Kate Weller, Trina Maturanec, Michael Rice, Balasubramanian Venkatesh, Paul Lane, Lyndell Redpath, Robert Seaton, Donna Mason, Naitik Mehta, Vikrant Kalke, Damian Jones, Mathew Ames, Mary Steele, Amy Wilkinson, Kristen Gibbons, Patricia Gilholm, Endrias Ergetu, Rachel Treadwell, Tahlia Van Raders, Jessicah Minogue

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Essential Emergency and Critical Care: a consensus among global clinical experts Por Samuel Akech, Mike English, Thomas G Weiser, Adam D Laytin, Niranjan Kissoon, Jaran Eriksen, Lovenish Bains, Fred Bulamba, Claudia Hanson, Maria Jirwe, Jolene Moore, Mpoki Ulisubisya, Vincent Ioos, Kent Doi, Lee A Wallis, Tom Bashford, Kapil Dev Soni, Nobhojit Roy, Franco Diaz, Mulinda Nyirenda, Nicholas Risko, Hendry R Sawe, Jacob McKnight, Alexandra Wharton-Smith, Jamie Rylance, Monty Khajanchi, Gavin Wooldridge, Emmanuel Fru Nsutebu, Lisa Kurland, Peter Baker, John C Marshall, Kathryn Rowan, Usha Lalla, Balasubramanian Venkatesh, Cornelius Sendagire, Neill KJ Adhikari, Tim Baker, Brian Rice, Josephine Langton, Elisabeth Riviello, Fiona Muttalib, Francis Mupeta, Jacquie Oliwa, Stefan Swartling Peterson, Andrew G Smith, Lorna Guinness, Megan Cox, Wim Van Damme, John Kellett, Elizabeth M Molyneux, Richard Venn, Andrea B Pembe, Mervyn Mer, Ignacio Martin-Loeches, Raymond Towey, Lina Zhang, Blaise Pascal, Hiral A Shah, Carl Otto Schell, Karima Khalid, Paul D Sonenthal, Alex Sanga, Raphael K. Kayambankadzanja, Adam Asghar, Adrian J Holloway, Ahmed Rhassane El Adib, Alexia Michaelides, Alvaro Coronado Munoz, Amos Muzuka, Analía Fernández, Andreas Wellhagen, Anita Gadgil, Anna Hvarfner, Anuja Abayadeera, Asya Agulnik, Aurélie Godard, Bargo Mahamat Yousif, Bhakti Sarang Ben Morton, Bharath Kumar, Tirupakuzhi Vijayaraghavan, Bobby King, C Louise Thwaites, Chian Wern Tai, Christian Owoo, Dan Brun Petersen, Daniel Tatay, David Lee Skinner, Denis Kinyua, Dhruva Ghosh, Diptesh Aryal, Donald Mlombwa, Duyen Thi, Hanh Bui, Edwin R Lugazia, Ellena Heyns, Erika Montalvo, Ernesto Gerardo Moreno, Esther Banda Kanyangira, Furaha Nzanzu, Gibonce Mwakisambwe, Guy A Richards, Hala Ammar, Halinder S Mangat, Hasanein H Ghali, Hoi Ping Shum, Ibrahim Salim Abdullahi, Ingrid T von der Osten, James S Lee, Jane Kasozi Namagga, Jasmine Armour-Marshall, John Z Metcalfe, Jonas Blixt, Juan Gutierrez Mejia, Juan Ignacio Silesky-Jiménez, Karl Martin Kohne, Kazuhiro Yokobatake, Kristina E. Rudd, Kwame Asante Akuamoah-Boateng, Lars Irestedt, Lia I Losonczy, Margaret Nyaika, Markus Castegren, Matthew Loftus, Matti Reinikainen, Michael Jaung, Michael S Lipnick, Miklos Lipcey, Märit Amanda Halmin, Naman Shah, Natalie L Cobb, Nathan D Nielsen, Neville Vlok, Ntogwiachu Daniel Kobuh, Oscar Fernández Rostello, Patricia Duque, Paul Patrick Mwasapi, Petronella Bjurling-Sjöberg, Piedad Sarmiento, Pryanka Relan, Rebecca Silvers, Rehema Mlay, Rich Branson, Richard J Wang, Richard Kojan, Richard Peter Von Rahden, Rob Mac Sweeney, Rodrigo Genaro Arduini, Rodwell Gundo, Ruyumbu Sixtus, Samson Kwazizira Mndolo, Shada A. Rouhani, Siriel Nanzia Massawe, Steven A Webb, Sunkaru Touray, Susana Guido, Teresa Kortz, Theodoros Aslanidis, Traci A Wolbrink, V Theodore Barnett, Vijay Christopher Kannan, Waleed S Eldebsy, Wangari Waweru-Siika, Wezzie Kumwenda Mwafulirwa, William Obeng, Yasein Omer, Zione Banda

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Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials Por Cathrine Axfors, Perrine Janiaud, Andreas M. Schmitt, Janneke van’t Hooft, Emily R. Smith, Noah A. Haber, Akin Abayomi, Manal Abduljalil, Abdulkarim Abdulrahman, Yeny Acosta-Ampudia, Manuela Aguilar-Guisado, Farah Al-Beidh, Marissa M. Alejandria, Rachelle N. Alfonso, Mohammad Ali, Manaf AlQahtani, Alaa AlZamrooni, Juan-Manuel Anaya, Mark Angelo C. Ang, Ismael F. Aomar, Luis E. Argumanis, Alexander Averyanov, Vladimir P. Baklaushev, Olga Balionis, Thomas Benfield, Scott Berry, Nadia Birocco, Lynn B. Bonifacio, Asha C. Bowen, Abbie Bown, Carlos Cabello-Gutierrez, Bernardo Camacho, Adrian Camacho-Ortiz, Sally Campbell-Lee, Damon H. Cao, Ana Cardesa, Jose M. Carnate, German Jr. J. Castillo, Rossana Cavallo, Fazle R. Chowdhury, Forhad U. H. Chowdhury, Giovannino Ciccone, Antonella Cingolani, Fresthel Monica M. Climacosa, Veerle Compernolle, Carlo Francisco N. Cortez, Abel Costa Neto, Sergio D’Antico, James Daly, Franca Danielle, Joshua S. Davis, Francesco Giuseppe De Rosa, Justin T. Denholm, Claudia M. Denkinger, Daniel Desmecht, Juan C. Díaz-Coronado, Juan A. Díaz Ponce-Medrano, Anne-Françoise Donneau, Teresita E. Dumagay, Susanna Dunachie, Cecile C. Dungog, Olufemi Erinoso, Ivy Mae S. Escasa, Lise J. Estcourt, Amy Evans, Agnes L. M. Evasan, Christian J. Fareli, Veronica Fernandez-Sanchez, Claudia Galassi, Juan E. Gallo, Patricia J. Garcia, Patricia L. Garcia, Jesus A. Garcia, Mutien Garigliany, Elvira Garza-Gonzalez, Deonne Thaddeus V. Gauiran, Paula A. Gaviria García, Jose-Antonio Giron-Gonzalez, David Gómez-Almaguer, Anthony C. Gordon, André Gothot, Jeser Santiago Grass Guaqueta, Cameron Green, David Grimaldi, Naomi E. Hammond, Heli Harvala, Francisco M. Heralde, Jesica Herrick, Alisa M. Higgins, Thomas E. Hills, Jennifer Hines, Karin Holm, Ashraful Hoque, Eric Hoste, Jose M. Ignacio, Alexander V. Ivanov, Maike Janssen, Jeffrey H. Jennings, Vivekanand Jha, Ruby Anne N. King, Jens Kjeldsen-Kragh, Paul Klenerman, Aditya Kotecha, Fiorella Krapp, Luciana Labanca, Emma Laing, Mona Landin-Olsson, Pierre-François Laterre, Lyn-Li Lim, Jodor Lim, Oskar Ljungquist, Jorge M. Llaca-Díaz, Concepción López-Robles, Salvador López-Cárdenas, Ileana Lopez-Plaza, Josephine Anne C. Lucero, Maria Lundgren, Juan Macías, Sandy C. Maganito, Anna Flor G. Malundo, Rubén D. Manrique, Paola M. Manzini, Miguel Marcos, Ignacio Marquez, Francisco Javier Martínez-Marcos, Ana M. Mata, Colin J. McArthur, Zoe K. McQuilten, Bryan J. McVerry, David K. Menon, Geert Meyfroidt, Ma. Angelina L. Mirasol, Benoît Misset, James S. Molton, Alric V. Mondragon, Diana M. Monsalve, Parastoo Moradi Choghakabodi, Susan C. Morpeth, Paul R. Mouncey, Michel Moutschen, Carsten Müller-Tidow, Erin Murphy, Tome Najdovski, Alistair D. Nichol, Henrik Nielsen, Richard M. Novak, Matthew V. N. O’Sullivan, Julian Olalla, Akin Osibogun, Bodunrin Osikomaiya, Salvador Oyonarte, Juan M. Pardo-Oviedo, Mahesh C. Patel, David L. Paterson, Carlos A. Peña-Perez, Angel A. Perez-Calatayud, Eduardo Pérez-Alba, Anastasia Perkina, Naomi Perry, Mandana Pouladzadeh, Inmaculada Poyato, David J. Price, Anne Kristine H. Quero, Md. M. Rahman, Md. S. Rahman, Mayur Ramesh, Carolina Ramírez-Santana, Magnus Rasmussen, Megan A. Rees, Eduardo Rego, Jason A. Roberts, David J. Roberts, Yhojan Rodríguez, Jesús Rodríguez-Baño, Benjamin A. Rogers, Manuel Rojas, Alberto Romero, Kathryn M. Rowan, Fabio Saccona, Mehdi Safdarian, Maria Clariza M. Santos, Joe Sasadeusz, Gitana Scozzari, Manu Shankar-Hari, Gorav Sharma, Thomas Snelling, Alonso Soto, Pedrito Y. Tagayuna, Amy Tang, Geneva Tatem, Luciana Teofili, Steven Y. C. Tong, Alexis F. Turgeon, Januario D. Veloso, Balasubramanian Venkatesh, Yanet Ventura-Enriquez, Steve A. Webb, Lothar Wiese, Christian Wikén, Erica M. Wood, Gaukhar M. Yusubalieva, Kai Zacharowski, Ryan Zarychanski, Nina Khanna, David Moher, Steven N. Goodman, John P. A. Ioannidis, Lars G. Hemkens

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