Flow-Cytometric Monitoring of Minimal Residual Disease in Pediatric Patients With Acute Myeloid Leukemia: Recent Advances and Future Strategies by Barbara Buldini, Margarita Maurer-Granofszky, Elena Varotto, Michael N. Dworzak

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Diagnostic challenges in acute monoblastic/monocytic leukemia in children by Elena Varotto, Eleonora Munaretto, Francesca Stefanachi, Fiammetta Della Torre, Barbara Buldini

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Phosphoproteomic Analysis Reveals a Different Proteomic Profile in Pediatric Patients With T-Cell Lymphoblastic Lymphoma or T-Cell Acute Lymphoblastic Leukemia by Giulia Veltri, Giulia Veltri, Federica Lovisa, Giuliana Cortese, Marta Pillon, Elisa Carraro, Simone Cesaro, Massimo Provenzi, Salvatore Buffardi, Samuela Francescato, Alessandra Biffi, Alessandra Biffi, Barbara Buldini, Barbara Buldini, Valentino Conter, Valentina Serafin, Valentina Serafin, Lara Mussolin, Lara Mussolin

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P414: PATIENT-DERIVED XENOGRAFT MODELS ARE THE LEADING STRATEGY TO IDENTIFY NEW AGENTS FOR PEDIATRIC ACUTE MYELOID LEUKEMIA by Ambra Da Ros, Valentina Indio, Alberto Peloso, Claudia Tregnago, Giulia Borella, Maddalena Benetton, Giorgia Longo, Silvia Bresolin, Barbara Buldini, Andrea Pession, Franco Locatelli, Martina Pigazzi

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Repurposing Verapamil to Enhance Killing of T-ALL Cells by the mTOR Inhibitor Everolimus by Micol Silic-Benussi, Evgeniya Sharova, Alberto Corradin, Loredana Urso, Vittoria Raimondi, Ilaria Cavallari, Barbara Buldini, Samuela Francescato, Sonia A. Minuzzo, Donna M. D’Agostino, Vincenzo Ciminale

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The rare cases of co-occurrences of Down Syndrome Disease and Juvenile Myelomonocytic Leukemia by Barbara Buldini, Manuela Tumino, Elena Varotto, Samuela Francescato, Alberto Peloso, Annamaria Di Meglio, Anna Leszl, Maria Gabelli, Alice Cani, Riccardo Masetti, Alessandra Biffi, Laura Sainati, Silvia Bresolin

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A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia by Valeria Tosello, Gloria Milani, Annalisa Martines, Nadia Macri, Wouder Van Loocke, Filip Matthijssens, Barbara Buldini, Sonia Minuzzo, Deborah Bongiovanni, Richard Fabian Schumacher, Alberto Amadori, Pieter Van Vlierberghe, Erich Piovan

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FLT3-ITD in Children with Early T-cell Precursor (ETP) Acute Lymphoblastic Leukemia: Incidence and Potential Target for Monitoring Minimal Residual Disease (MRD) by Luca Lo Nigro, Nellina Andriano, Barbara Buldini, Daniela Silvestri, Tiziana Villa, Franco Locatelli, Rosanna Parasole, Elena Barisone, Anna Maria Testi, Andrea Biondi, Maria Grazia Valsecchi, Carmelo Rizzari, Valentino Conter, Giuseppe Basso, Giovanni Cazzaniga

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mTOR inhibition downregulates glucose-6-phosphate dehydrogenase and induces ROS-dependent death in T-cell acute lymphoblastic leukemia cells by Micol Silic-Benussi, Evgenyia Sharova, Francesco Ciccarese, Ilaria Cavallari, Vittoria Raimondi, Loredana Urso, Alberto Corradin, Harel Kotler, Gloria Scattolin, Barbara Buldini, Samuela Francescato, Giuseppe Basso, Sonia A. Minuzzo, Stefano Indraccolo, Donna M. D'Agostino, Vincenzo Ciminale

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Prognostic Role of Minimal Disseminated Disease and <i>NOTCH1/FBXW7</i> Mutational Status in Children with Lymphoblastic Lymphoma: The AIEOP Experience by Federica Lovisa, Ilaria Gallingani, Elena Varotto, Cristiano Pasin, Elisa Carraro, Barbara Michielotto, Anna Garbin, Carlotta Caterina Damanti, Marco Pizzi, Emanuele S. G. d’Amore, Matilde Piglione, Paola Muggeo, Salvatore Buffardi, Luciana Vinti, Veronica Maria Folsi, Daniela Onofrillo, Alessandra Biffi, Barbara Buldini, Marta Pillon, Lara Mussolin

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Definition and Prognostic Value of Ph-like and IKZF1plus Status in Children With Down Syndrome and B-cell Precursor Acute Lymphoblastic Leukemia by Chiara Palmi, Silvia Bresolin, Stefanie Junk, Grazia Fazio, Daniela Silvestri, Marketa Zaliova, Athanasios Oikonomou, Katerina Scharov, Martin Stanulla, Anja Moericke, Martin Zimmermann, Martin Schrappe, Barbara Buldini, Sanil Bhatia, Arndt Borkhardt, Claudia Saitta, Marta Galbiati, Michela Bardini, Luca Lo Nigro, Valentino Conter, Maria Grazia Valsecchi, Andrea Biondi, Geertruy te Kronnie, Gunnar Cario, Giovanni Cazzaniga

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PAX5 fusion genes are frequent in poor risk childhood acute lymphoblastic leukaemia and can be targeted with BIBF1120 by Grazia Fazio, Silvia Bresolin, Daniela Silvestri, Manuel Quadri, Claudia Saitta, Elena Vendramini, Barbara Buldini, Chiara Palmi, Michela Bardini, Andrea Grioni, Silvia Rigamonti, Marta Galbiati, Stefano Mecca, Angela Maria Savino, Alberto Peloso, Jia-Wey Tu, Sanil Bhatia, Arndt Borkhardt, Concetta Micalizzi, Luca Lo Nigro, Franco Locatelli, Valentino Conter, Carmelo Rizzari, Maria Grazia Valsecchi, Geertruij te Kronnie, Andrea Biondi, Giovanni Cazzaniga

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An Extensive Quality Control and Quality Assurance (QC/QA) Program Significantly Improves Inter-Laboratory Concordance Rates of Flow-Cytometric Minimal Residual Disease Assessment... by Margarita Maurer-Granofszky, Angela Schumich, Barbara Buldini, Giuseppe Gaipa, Janos Kappelmayer, Ester Mejstrikova, Leonid Karawajew, Jorge Rossi, Adın Çınar Suzan, Evangelina Agriello, Theodora Anastasiou-Grenzelia, Virna Barcala, Gábor Barna, Drago Batinić, Jean-Pierre Bourquin, Monika Brüggemann, Karolina Bukowska-Strakova, Hasan Burnusuzov, Daniela Carelli, Günnur Deniz, Klara Dubravčić, Tamar Feuerstein, Marie Isabel Gaillard, Adriana Galeano, Hugo Giordano, Alejandro Gonzalez, Stefanie Groeneveld-Krentz, Zsuzsanna Hevessy, Ondrej Hrusak, Maria Belen Iarossi, Pál Jáksó, Veronika Kloboves Prevodnik, Saskia Kohlscheen, Elena Kreminska, Oscar Maglia, Cecilia Malusardi, Neda Marinov, Bibiana Maria Martin, Claudia Möller, Sergey Nikulshin, Jorge Palazzi, Georgios Paterakis, Alexander Popov, Richard Ratei, Cecilia Rodríguez, Elisa Olga Sajaroff, Simona Sala, Gordana Samardzija, Mary Sartor, Pamela Scarparo, Łukasz Sędek, Bojana Slavkovic, Liliana Solari, Peter Svec, Tomasz Szczepanski, Anna Taparkou, Montserrat Torrebadell, Marianna Tzanoudaki, Elena Varotto, Helly Vernitsky, Andishe Attarbaschi, Martin Schrappe, Valentino Conter, Andrea Biondi, Marisa Felice, Myriam Campbell, Csongor Kiss, Giuseppe Basso, Michael N. Dworzak, on behalf of I-BFM-FLOW-Network

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