SDH mutations in cancer. by Bardella, C, Pollard, P, Tomlinson, I

SDH mutations in cancer by Bardella, C, Pollard, P, Tomlinson, I

Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma. by Krell, D, Assoku, M, Galloway, M, Mulholland, P, Tomlinson, I, Bardella, C

The role of inflammation in subventricular zone cancer by Bardella, C, Al-Shammari, A, Soares, L, Tomlinson, I, O'Neill, E, Szele, F

Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression by Schödel, J, Bardella, C, Sciesielski, L, Brown, J, Pugh, C, Buckle, V, Tomlinson, I, Ratcliffe, P, Mole, DR

Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression. by Schödel, J, Bardella, C, Sciesielski, L, Brown, J, Pugh, C, Buckle, V, Tomlinson, I, Ratcliffe, P, Mole, DR

BONE MORPHOGENETIC PROTEIN (BMP) PATHWAY DYSREGULATION SUBVERTS ONCOGENE INDUCED SENESCENCE MECHANISMS IN THE SERRATED PATHWAY OF TUMOURIGENESIS by Boitsova, T, Rafferty, H, Davis, H, Bardella, C, Gill, P, East, J, Tomlinson, I, Chetty, R, Silver, A, Leedham, S

Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression by Schödel, J, Bardella, C, Sciesielski, L, Brown, J, Pugh, C, Buckle, V, Tomlinson, I, Ratcliffe, P, Mole, DR

Cells lacking the fumarase tumor suppressor are protected from apoptosis through a hypoxia-inducible factor-independent, AMPK-dependent mechanism. by Bardella, C, Olivero, M, Lorenzato, A, Geuna, M, Adam, J, O'Flaherty, L, Rustin, P, Tomlinson, I, Pollard, P, Di Renzo, M

Anion-exchange chromatography mass spectrometry provides extensive coverage of primary metabolic pathways revealing altered metabolism in IDH1 mutant cells by Walsby-Tickle, J, Gannon, J, Hvinden, I, Bardella, C, Abboud, MI, Nazeer, A, Hauton, D, Pires, E, Cadoux-Hudson, T, Schofield, CJ, McCullagh, JSO

Bone Morphogenetic Protein and Notch signaling crosstalk in poor-prognosis, mesenchymal-subtype colorectal cancer by Irshad, S, Bansal, M, Guarnieri, P, Davis, H, Al Haj Zen, A, Baran, B, Pinna, C, Rahman, H, Biswas, S, Bardella, C, Jeffery, R, Wang, L, East, J, Tomlinson, I, Lewis, A, Leedham, S

Bone morphogenetic protein and Notch signalling crosstalk in poor-prognosis, mesenchymal-subtype colorectal cancer. by Irshad, S, Bansal, M, Guarnieri, P, Davis, H, Al Haj Zen, A, Baran, B, Pinna, C, Rahman, H, Biswas, S, Bardella, C, Jeffery, R, Wang, L, East, J, Tomlinson, I, Lewis, A, Leedham, S

Resistance to the isocitrate dehydrogenase 1 mutant inhibitor ivosidenib can be overcome by alternative dimer-interface binding inhibitors by Reinbold, R, Hvinden, IC, Rabe, P, Herold, RA, Finch, A, Wood, J, Morgan, M, Staudt, M, Clifton, IJ, Armstrong, FA, McCullagh, JSO, Redmond, J, Bardella, C, Abboud, MI, Schofield, CJ

Expression of Idh1R132H in the murine subventricular zone stem cell niche recapitulates early gliomagenesis by Bardella, C, Al-Dalahmah, O, Krell, D, Brazauskas, P, Tomkova, M, Al-Qahtani, K, Adam, J, Serres, S, Lockstone, H, Freeman-Mills, L, Pfeffer, I, Sibson, N, Goldin, R, Schuster-Böeckler, B, Pollard, P, Soga, T, McCullagh, J, Schofield, C, Mulholland, P, Ansorge, O, Kriaucionis, S, Ratcliffe, P, Szele, F, Tomlinson, I

Expression of Idh1R132H in the murine subventricular zone stem cell niche recapitulates early gliomagenesis by Bardella, C, Al-Dalahmah, O, Krell, D, Brazauskas, P, Tomkova, M, Adam, J, Serres, S, Lockstone, H, Freeman-Mills, L, Pfeffer, I, Sibson, N, Goldin, R, Schuster-Böeckler, B, Pollard, P, Soga, T, McCullagh, J, Schofield, C, Mulholland, P, Ansorge, O, Kriaucionis, S, Ratcliffe, P, Szele, F, Tomlinson, I, Al-Qahtani, K

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche. by Davis, H, Irshad, S, Bansal, M, Rafferty, H, Boitsova, T, Bardella, C, Jaeger, E, Lewis, A, Freeman-Mills, L, Giner, F, Rodenas-Cuadrado, P, Mallappa, S, Clark, S, Thomas, H, Jeffery, R, Poulsom, R, Rodriguez-Justo, M, Novelli, M, Chetty, R, Silver, A, Sansom, O, Greten, F, Wang, L, East, J, Tomlinson, I, Leedham, S

Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status. by Bardella, C, El-Bahrawy, M, Frizzell, N, Adam, J, Ternette, N, Hatipoglu, E, Howarth, K, O'Flaherty, L, Roberts, I, Turner, G, Taylor, J, Giaslakiotis, K, Macaulay, V, Harris, A, Chandra, A, Lehtonen, H, Launonen, V, Aaltonen, L, Pugh, C, Mihai, R, Trudgian, D, Kessler, B, Baynes, J, Ratcliffe, P, Tomlinson, I

Expression profiling in progressive stages of fumarate-hydratase deficiency: the contribution of metabolic changes to tumorigenesis. by Ashrafian, H, O'Flaherty, L, Adam, J, Steeples, V, Chung, Y, East, P, Vanharanta, S, Lehtonen, H, Nye, E, Hatipoglu, E, Miranda, M, Howarth, K, Shukla, D, Troy, H, Griffiths, J, Spencer-Dene, B, Yusuf, M, Volpi, E, Maxwell, P, Stamp, G, Poulsom, R, Pugh, C, Costa, B, Bardella, C, Di Renzo, M

Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status. by Bardella, C, El-Bahrawy, M, Frizzell, N, Adam, J, Ternette, N, Hatipoglu, E, Howarth, K, O'Flaherty, L, Roberts, I, Turner, G, Taylor, J, Giaslakiotis, K, Macaulay, V, Harris, A, Chandra, A, Lehtonen, H, Launonen, V, Aaltonen, L, Pugh, C, Mihai, R, Trudgian, D, Kessler, B, Baynes, J, Ratcliffe, P, Tomlinson, I, Pollard, P