Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants? af Southam, L, Soranzo, N, Montgomery, S, Frayling, T, McCarthy, M, Barroso, I, Zeggini, E

PARL Leu262Val is not associated with fasting insulin levels in UK populations. af Fawcett, K, Wareham, N, Luan, J, Syddall, H, Cooper, C, O'Rahilly, S, Day, I, Sandhu, MS, Barroso, I

Whole genome-amplified DNA: insights and imputation. af Teo, Y, Inouye, M, Small, K, Fry, A, Potter, S, Dunstan, S, Seielstad, M, Barroso, I, Wareham, N, Rockett, K, Kwiatkowski, D, Deloukas, P

Detailed investigation of the role of common and low-frequency WFS1 variants in type 2 diabetes risk. af Fawcett, K, Wheeler, E, Morris, A, Ricketts, S, Hallmans, G, Rolandsson, O, Daly, A, Wasson, J, Permutt, A, Hattersley, A, Glaser, B, Franks, P, McCarthy, M, Wareham, N, Sandhu, MS, Barroso, I

Spread of Chikungunya virus East/Central/South African genotype in Northeast Brazil. af Charlys da Costa, A, Thézé, J, Komninakis, S, Sanz-Duro, R, Felinto, M, Moura, L, Barroso, I, Santos, L, Nunes, M, Moura, A, Lourenço, J, Deng, X, Delwart, E, Guimarães, M, Pybus, O, Sabino, E, Faria, N

Genome-wide association study of type 2 diabetes in Africa af Chen, J, Sun, M, Adeyemo, A, Pirie, F, Carstensen, T, Pomilla, C, Doumatey, A.P, Chen, G, Young, E.H, Sandhu, M, Morris, A, Barroso, I, McCarthy, MARK, Mahajan, A, Wheelerr, E, Rotimi, C, Motala, A.A

Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections af Sallah, N, Miley, W, Labo, N, Carstensen, T, Fatumo, S, Gurdasani, D, Pollard, MO, Dilthey, AT, Mentzer, AJ, Marshall, V, Cornejo Castro, EM, Pomilla, C, Young, EH, Asiki, G, Hibberd, ML, Sandhu, M, Kellam, P, Newton, R, Whitby, D, Barroso, I

Impact of Type 2 Diabetes Susceptibility Loci on Variation in Physiologic Glycaemic Traits in Non-Diabetic Individuals af Dimas, A, Gomes, V, Knowles, J, Maegi, R, Barker, A, Hivert, M, Benazzo, A, Rybin, D, Assimes, T, Ouertermous, T, Walker, M, Florez, J, Barroso, I, Langenberg, C, Dupuis, J, Watanabe, R, Mccarthy, M, Ingelsson, E, Prokopenko, I, GENESIS, MAGIC, DIAGRAM

Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies. af Barroso, I, Luan, J, Wheeler, E, Whittaker, P, Wasson, J, Zeggini, E, Weedon, M, Hunt, S, Venkatesh, R, Frayling, T, Delgado, M, Neuman, R, Zhao, J, Sherva, R, Glaser, B, Walker, M, Hitman, G, McCarthy, M, Hattersley, A, Permutt, M, Wareham, N, Deloukas, P

Novel Genetic Loci Implicated in Fasting Glucose Homeostasis and Their Impact on Related Metabolic Traits af Dupuis, J, Langenberg, C, Prokopenko, I, Saxena, R, Soranzo, N, Jackson, A, Wheeler, E, Glazer, N, Bouatia-Naji, N, McCullogh, L, Gloyn, A, Sladek, R, Froguel, P, Watanabe, R, Meigs, J, Groop, L, Boehnke, M, McCarthy, M, Florez, J, Barroso, I, Investigators, MAGIC

Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function. af Soler Artigas, M, Wain, L, Repapi, E, Obeidat, M, Sayers, I, Burton, P, Johnson, T, Zhao, J, Albrecht, E, Dominiczak, A, Kerr, S, Smith, B, Cadby, G, Hui, J, Palmer, L, Hingorani, A, Wannamethee, S, Whincup, P, Ebrahim, S, Smith, G, Barroso, I, Loos, R, Wareham, N, Cooper, C, Dennison, E

Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity af Scott, R, Fall, T, Pasko, D, Barker, A, Sharp, S, Arriola, L, Balkau, B, Barricarte, A, Barroso, I, Boeing, H, Clavel-Chapelon, F, Crowe, F, Dekker, J, Fagherazzi, G, Ferrannini, E, Forouhi, N, Franks, P, Gavrila, D, Giedraitis, V, Grioni, S, Groop, L, Kaaks, R, Key, T, Kühn, T, Lotta, L

Common variants in WFS1 confer risk of type 2 diabetes. af Sandhu, MS, Weedon, M, Fawcett, K, Wasson, J, Debenham, S, Daly, A, Lango, H, Frayling, T, Neumann, R, Sherva, R, Blech, I, Pharoah, P, Palmer, C, Kimber, C, Tavendale, R, Morris, A, McCarthy, M, Walker, M, Hitman, G, Glaser, B, Permutt, M, Hattersley, A, Wareham, N, Barroso, I

Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity. af Scott, R, Fall, T, Pasko, D, Barker, A, Sharp, S, Arriola, L, Balkau, B, Barricarte, A, Barroso, I, Boeing, H, Clavel-Chapelon, F, Crowe, F, Dekker, J, Fagherazzi, G, Ferrannini, E, Forouhi, N, Franks, P, Gavrila, D, Giedraitis, V, Grioni, S, Groop, L, Kaaks, R, Key, T, Kühn, T, Lotta, L

Effect of 5 Genetic Variants Associated with Lung Function on the Risk of COPD, and their Joint Effects on Lung Function. af Soler Artigas, M, Wain, L, Repapi, E, Obeidat, M, Sayers, I, Burton, P, Johnson, T, Zhao, J, Albrecht, E, Dominiczak, A, Kerr, S, Smith, B, Cadby, G, Hui, J, Palmer, L, Hingorani, A, Wannamethee, S, Whincup, P, Ebrahim, S, Smith, G, Barroso, I, Loos, R, Wareham, N, Cooper, C, Dennison, E

Effect of 5 Genetic Variants Associated with Lung Function on the Risk of COPD, and their Joint Effects on Lung Function. af Soler Artigas, M, Wain, L, Repapi, E, Obeidat, M, Sayers, I, Burton, P, Johnson, T, Zhao, J, Albrecht, E, Dominiczak, A, Kerr, S, Smith, B, Cadby, G, Hui, J, Palmer, L, Hingorani, A, Wannamethee, S, Whincup, P, Ebrahim, S, Smith, G, Barroso, I, Loos, R, Wareham, N, Cooper, C, Dennison, E

Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes. af Bonnefond, A, Clément, N, Fawcett, K, Yengo, L, Vaillant, E, Guillaume, J, Dechaume, A, Payne, F, Roussel, R, Czernichow, S, Hercberg, S, Hadjadj, S, Balkau, B, Marre, M, Lantieri, O, Langenberg, C, Bouatia-Naji, N, Charpentier, G, Vaxillaire, M, Rocheleau, G, Wareham, N, Sladek, R, McCarthy, M, Dina, C, Barroso, I

Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes af Bonnefond, A, Clément, N, Fawcett, K, Yengo, L, Vaillant, E, Guillaume, J, Dechaume, A, Payne, F, Roussel, R, Czernichow, S, Hercberg, S, Hadjadj, S, Balkau, B, Marre, M, Lantieri, O, Langenberg, C, Bouatia-Naji, N, Charpentier, G, Vaxillaire, M, Rocheleau, G, Wareham, N, Sladek, R, McCarthy, M, Dina, C, Barroso, I

Underlying genetic models of inheritance in established type 2 diabetes associations. af Salanti, G, Southam, L, Altshuler, D, Ardlie, K, Barroso, I, Boehnke, M, Cornelis, M, Frayling, T, Grallert, H, Grarup, N, Groop, L, Hansen, T, Hattersley, A, Hu, F, Hveem, K, Illig, T, Kuusisto, J, Laakso, M, Langenberg, C, Lyssenko, V, McCarthy, M, Morris, A, Morris, A, Palmer, C, Payne, F

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. af Dimas, A, Lagou, V, Barker, A, Knowles, J, Mägi, R, Hivert, M, Benazzo, A, Rybin, D, Jackson, A, Stringham, H, Song, C, Fischer-Rosinsky, A, Boesgaard, T, Grarup, N, Abbasi, F, Assimes, T, Hao, K, Yang, X, Lecoeur, C, Barroso, I, Bonnycastle, L, Böttcher, Y, Bumpstead, S, Chines, P, Erdos, MR