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Bart De Strooper

Bart De Strooper is a Belgian molecular biologist and professor at Vlaams Instituut voor Biotechnologie and KU Leuven (Leuven, Belgium) and the UK Dementia Research Institute and University College London, UK. De Strooper's research seeks to translate genetic data into the identification and treatment of neurodegenerative diseases and treatments. interest are the secretases, proteases which cleave the amyloid precursor protein (APP), resulting in amyloid peptides. Provided by Wikipedia

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From Junk to Function: LncRNAs in CNS Health and Disease by Rafaela Policarpo, Rafaela Policarpo, Rafaela Policarpo, Annerieke Sierksma, Annerieke Sierksma, Bart De Strooper, Bart De Strooper, Bart De Strooper, Constantin d’Ydewalle

Published 2021-07-01

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2

The promise of microRNA-based therapies in Alzheimer’s disease: challenges and perspectives by Hannah Walgrave, Lujia Zhou, Bart De Strooper, Evgenia Salta

Published 2021-11-01

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3

LRRK2 expression is enriched in the striosomal compartment of mouse striatum by Wim Mandemakers, An Snellinx, Michael J. O'Neill, Bart de Strooper

Published 2012-12-01

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4

In Vitro Comparison of the Activity Requirements and Substrate Specificity of Human and Triboleum castaneum PINK1 Orthologues. by Liesbeth Aerts, Katleen Craessaerts, Bart De Strooper, Vanessa A Morais

Published 2016-01-01

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5

Regulation of amyloid precursor protein processing by serotonin signaling. by Anna A Pimenova, Amantha Thathiah, Bart De Strooper, Ina Tesseur

Published 2014-01-01

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6

Aducanumab: a new phase in therapeutic development for Alzheimer’s disease? by Giovanna Lalli, Jonathan M Schott, John Hardy, Bart De Strooper

Published 2021-08-01

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7

miR‐132 loss de‐represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain by Evgenia Salta, Annerieke Sierksma, Elke Vanden Eynden, Bart De Strooper

Published 2016-09-01

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8

VHHs as tools for therapeutic protein delivery to the central nervous system by Yessica Wouters, Tom Jaspers, Laura Rué, Lutgarde Serneels, Bart De Strooper, Maarten Dewilde

Published 2022-10-01

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9

MicroRNA regulation of Alzheimer's Amyloid precursor protein expression by Sébastien S. Hébert, Katrien Horré, Laura Nicolaï, Bruno Bergmans, Aikaterini S. Papadopoulou, André Delacourte, Bart De Strooper

Published 2009-03-01

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10

Gene and MicroRNA transcriptome analysis of Parkinson's related LRRK2 mouse models. by Véronique Dorval, Wim Mandemakers, Francis Jolivette, Laetitia Coudert, Rachid Mazroui, Bart De Strooper, Sébastien S Hébert

Published 2014-01-01

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Novel Human/Non-Human Primate Cross-Reactive Anti-Transferrin Receptor Nanobodies for Brain Delivery of Biologics by Laura Rué, Tom Jaspers, Isabelle M. S. Degors, Sam Noppen, Dominique Schols, Bart De Strooper, Maarten Dewilde

Published 2023-06-01

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Modeling the β-secretase cleavage site and humanizing amyloid-beta precursor protein in rat and mouse to study Alzheimer’s disease by Lutgarde Serneels, Dries T’Syen, Laura Perez-Benito, Tom Theys, Matthew G. Holt, Bart De Strooper

Published 2020-10-01

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Cell autonomous regulation of hippocampal circuitry via Aph1b-γ-secretase/neuregulin 1 signalling by Pietro Fazzari, An Snellinx, Victor Sabanov, Tariq Ahmed, Lutgarde Serneels, Annette Gartner, S Ali M Shariati, Detlef Balschun, Bart De Strooper

Published 2014-06-01

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Identifying individuals with high risk of Alzheimer’s disease using polygenic risk scores by Ganna Leonenko, Emily Baker, Joshua Stevenson-Hoare, Annerieke Sierksma, Mark Fiers, Julie Williams, Bart de Strooper, Valentina Escott-Price

Published 2021-07-01

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Coordinated and widespread expression of γ-secretase in vivo: evidence for size and molecular heterogeneity by Sébastien S. Hébert, Lutgarde Serneels, Tim Dejaegere, Katrien Horré, Michal Dabrowski, Veerle Baert, Wim Annaert, Dieter Hartmann, Bart De Strooper

Published 2004-11-01

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Inactivation of γ‐secretases leads to accumulation of substrates and non‐Alzheimer neurodegeneration by Hermien Acx, Lutgarde Serneels, Enrico Radaelli, Serge Muyldermans, Cécile Vincke, Elise Pepermans, Ulrike Müller, Lucía Chávez‐Gutiérrez, Bart De Strooper

Published 2017-08-01

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Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer’s Disease by Philip W. Brownjohn, James Smith, Erik Portelius, Lutgarde Serneels, Hlin Kvartsberg, Bart De Strooper, Kaj Blennow, Henrik Zetterberg, Frederick J. Livesey

Published 2017-04-01

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Notch is a critical component of the mouse somitogenesis oscillator and is essential for the formation of the somites. by Zoltan Ferjentsik, Shinichi Hayashi, J Kim Dale, Yasumasa Bessho, An Herreman, Bart De Strooper, Gonzalo del Monte, Jose Luis de la Pompa, Miguel Maroto

Published 2009-09-01

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Novel Alzheimer risk genes determine the microglia response to amyloid‐β but not to TAU pathology by Annerieke Sierksma, Ashley Lu, Renzo Mancuso, Nicola Fattorelli, Nicola Thrupp, Evgenia Salta, Jesus Zoco, David Blum, Luc Buée, Bart De Strooper, Mark Fiers

Published 2020-03-01

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Correction: Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity. by Isabel H Salas, Zsuzsanna Callaerts-Vegh, Amaia M Arranz, Francesc X Guix, Rudi D'Hooge, José A Esteban, Bart De Strooper, Carlos G Dotti

Published 2017-01-01

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