Function of the endolysosomal network in cholesterol homeostasis and metabolic-associated fatty liver disease (MAFLD) by Dyonne Y. Vos, Bart van de Sluis

Get full text

The Direct and Indirect Roles of NF-κB in Cancer: Lessons from Oncogenic Fusion Proteins and Knock-in Mice by Tabea Riedlinger, Jana Haas, Julia Busch, Bart van de Sluis, Michael Kracht, M. Lienhard Schmitz

Get full text

Reduced life- and healthspan in mice carrying a mono-allelic BubR1 MVA mutation. by Tobias Wijshake, Liviu A Malureanu, Darren J Baker, Karthik B Jeganathan, Bart van de Sluis, Jan M van Deursen

Get full text

Long Non-Coding RNAs Involved in Progression of Non-Alcoholic Fatty Liver Disease to Steatohepatitis by Biljana Atanasovska, Sander S. Rensen, Glenn Marsman, Ronit Shiri-Sverdlov, Sebo Withoff, Folkert Kuipers, Cisca Wijmenga, Bart van de Sluis, Jingyuan Fu

Get full text

Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in HepatocytesSummary by Ali Saeed, Paulina Bartuzi, Janette Heegsma, Daphne Dekker, Niels Kloosterhuis, Alain de Bruin, Johan W. Jonker, Bart van de Sluis, Klaas Nico Faber

Get full text

Regulation of murine copper homeostasis by members of the COMMD protein family by Amika Singla, Qing Chen, Kohei Suzuki, Jie Song, Alina Fedoseienko, Melinde Wijers, Adam Lopez, Daniel D. Billadeau, Bart van de Sluis, Ezra Burstein

Get full text

COMMD1 Promotes pVHL and O2-Independent Proteolysis of HIF-1alpha via HSP90/70. by Bart van de Sluis, Arjan J Groot, Jeroen Vermeulen, Elsken van der Wall, Paul J van Diest, Cisca Wijmenga, Leo W Klomp, Marc Vooijs

Get full text

Deregulated Renal Calcium and Phosphate Transport during Experimental Kidney Failure. by Wilco P Pulskens, Melissa Verkaik, Fareeba Sheedfar, Ellen P van Loon, Bart van de Sluis, Mark G Vervloet, Joost G Hoenderop, René J Bindels, NIGRAM Consortium

Get full text

The Copper Metabolism MURR1 domain protein 1 (COMMD1) modulates the aggregation of misfolded protein species in a client-specific manner. by Willianne I M Vonk, Vaishali Kakkar, Paulina Bartuzi, Dick Jaarsma, Ruud Berger, Marten H Hofker, Leo W J Klomp, Cisca Wijmenga, Harm H Kampinga, Bart van de Sluis

Get full text

Liver-specific Commd1 knockout mice are susceptible to hepatic copper accumulation. by Willianne I M Vonk, Paulina Bartuzi, Prim de Bie, Niels Kloosterhuis, Catharina G K Wichers, Ruud Berger, Susan Haywood, Leo W J Klomp, Cisca Wijmenga, Bart van de Sluis

Get full text

Cardiac function and architecture are maintained in a model of cardiorestricted overexpression of the prorenin-renin receptor. by Hasan Mahmud, Wellington Mardoqueu Candido, Linda van Genne, Inge Vreeswijk-Baudoin, Hongjuan Yu, Bart van de Sluis, Jan van Deursen, Wiek H van Gilst, Herman H W Silljé, Rudolf A de Boer

Get full text

Nuclear COMMD1 Is Associated with Cisplatin Sensitivity in Ovarian Cancer. by Alina Fedoseienko, Hylke W Wieringa, G Bea A Wisman, Evelien Duiker, Anna K L Reyners, Marten H Hofker, Ate G J van der Zee, Bart van de Sluis, Marcel A T M van Vugt

Get full text

Cholesterol-Induced Hepatic Inflammation Does Not Underlie the Predisposition to Insulin Resistance in Dyslipidemic Female LDL Receptor Knockout Mice by Nanda Gruben, Anouk Funke, Niels J. Kloosterhuis, Marijke Schreurs, Fareeba Sheedfar, Rick Havinga, Sander M. Houten, Ronit Shiri-Sverdlov, Bart van de Sluis, Jan Albert Kuivenhoven, Debby P. Y. Koonen, Marten H. Hofker

Get full text

Chemokine-like receptor 1 deficiency does not affect the development of insulin resistance and nonalcoholic fatty liver disease in mice. by Nanda Gruben, Marcela Aparicio Vergara, Niels J Kloosterhuis, Henk van der Molen, Stefan Stoelwinder, Sameh Youssef, Alain de Bruin, Dianne J Delsing, Jan Albert Kuivenhoven, Bart van de Sluis, Marten H Hofker, Debby P Y Koonen

Get full text

A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism by Leen Catrysse, Bastiaan Maes, Parul Mehrotra, Arne Martens, Esther Hoste, Liesbet Martens, Christian Maueröder, Anneleen Remmerie, Anna Bujko, Karolina Slowicka, Mozes Sze, Hanna Vikkula, Bart Ghesquière, Charlotte L. Scott, Yvan Saeys, Bart van de Sluis, Kodi Ravichandran, Sophie Janssens, Geert van Loo

Get full text

The hepatocyte IKK:NF-κB axis promotes liver steatosis by stimulating de novo lipogenesis and cholesterol synthesis by Andries Heida, Nanda Gruben, Leen Catrysse, Martijn Koehorst, Mirjam Koster, Niels J. Kloosterhuis, Albert Gerding, Rick Havinga, Vincent W. Bloks, Laura Bongiovanni, Justina C. Wolters, Theo van Dijk, Geert van Loo, Alain de Bruin, Folkert Kuipers, Debby P.Y. Koonen, Bart van de Sluis

Get full text

Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism by Anke Loregger, Matthijs Raaben, Joppe Nieuwenhuis, Josephine M. E. Tan, Lucas T. Jae, Lisa G. van den Hengel, Sebastian Hendrix, Marlene van den Berg, Saskia Scheij, Ji-Ying Song, Ivo J. Huijbers, Lona J. Kroese, Roelof Ottenhoff, Michel van Weeghel, Bart van de Sluis, Thijn Brummelkamp, Noam Zelcer

Get full text

Normalization of hepatic ChREBP activity does not protect against liver disease progression in a mouse model for Glycogen Storage Disease type Ia by Martijn G. S. Rutten, Yu Lei, Joanne H. Hoogerland, Vincent W. Bloks, Hong Yang, Trijnie Bos, Kishore A. Krishnamurthy, Aycha Bleeker, Mirjam H. Koster, Rachel E. Thomas, Justina C. Wolters, Hilda van den Bos, Gilles Mithieux, Fabienne Rajas, Adil Mardinoglu, Diana C. J. Spierings, Alain de Bruin, Bart van de Sluis, Maaike H. Oosterveer

Get full text

Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic AcidSummary by Jan Freark de Boer, Hilde D. de Vries, Anna Palmiotti, Rumei Li, Marwah Doestzada, Joanne A. Hoogerland, Jingyuan Fu, Anouk M. La Rose, Marit Westerterp, Niels L. Mulder, Milaine V. Hovingh, Martijn Koehorst, Niels J. Kloosterhuis, Justina C. Wolters, Vincent W. Bloks, Joel T. Haas, David Dombrowicz, Bart Staels, Bart van de Sluis, Folkert Kuipers

Get full text

Mitochondrial DNA methylation in metabolic associated fatty liver disease by Archibold Mposhi, Archibold Mposhi, Fabian Cortés-Mancera, Fabian Cortés-Mancera, Janette Heegsma, Vincent E. de Meijer, Bart van de Sluis, Svenja Sydor, Svenja Sydor, Lars P. Bechmann, Lars P. Bechmann, Claudia Theys, Peter de Rijk, Peter de Rijk, Tim De Pooter, Tim De Pooter, Wim Vanden Berghe, İkbal Agah İnce, İkbal Agah İnce, Klaas Nico Faber, Marianne G. Rots

Get full text