Genome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biology by Beer, N, Gloyn, A

American Diabetes Association Meeting Report by Beer, N, Hilton, C

The role of genetic variation in glucokinase and glucokinase regulatory protein in diabetes and related traits by Beer, N, Nicola L Beer

HIGH-SPEED 5-AXIS MACHINING FOR TOOLING APPLICATIONS by Saxer, M., De Beer, N., Dimitrov, D. M.

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Investigating novel mutational mechanisms for glucokinase mutations with near normal or paradoxical kinetics by Tribble, N, Beer, N, Grimsby, J, Baltrusch, S, Gloyn, A

Functional characterisation of the glucokinase regulatory protein gene variant P446L shows diminished regulation by fructose-6 phosphate resulting in increased glucokinase activity by Beer, N, Tribble, N, Roos, C, Orho-Melander, M, Gloyn, A

Mutations in the third gene shown to alter fasting glucose levels in the population (G6PC2) are not a common cause of monogenic forms of pancreatic B-cell dysfunction. by Edghill, E, McCulloch, L, Fulton, P, Beer, N, Hattersley, A, Gloyn, A

Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk by Rees, MG, Wincovitch, S, Schultz, J, Waterstradt, R, Beer, N, Baltrusch, S, Collins, F, Gloyn, A

Derivation and molecular characterization of pancreatic differentiated MODY1-iPSCs by Braverman-Gross, C, Nudel, N, Ronen, D, Beer, N, McCarthy, M, Benvenisty, N

Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk. by Rees, MG, Wincovitch, S, Schultz, J, Waterstradt, R, Beer, N, Baltrusch, S, Collins, F, Gloyn, A

Naturally occurring glucokinase mutations at the same amino acid residue cause opposite clinical phenotypes of hypo- and hyperglycaemia by Beer, N, Tribble, N, Colclough, K, Arundel, P, Grimsby, J, Chik, C, Ellard, S, Gloyn, A

Update on mutations in glucokinase (GCK), which cause maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia. by Osbak, K, Colclough, K, Saint-Martin, C, Beer, N, Bellanné-Chantelot, C, Ellard, S, Gloyn, A

The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver. by Beer, N, Tribble, N, McCulloch, L, Roos, C, Johnson, P, Orho-Melander, M, Gloyn, A

Identification and functional characterisation of novel inactivating glucokinase mutations causing GCK-MODY in Slovakia by Valentinova, L, Beer, N, Stanik, J, Tribble, N, Huckova, M, Gasperikova, D, Klimes, I, Gloyn, A

Attitudes towards attractive and credible celebrities in advertisements by De la Rey van der Waldt, N de Beer N de Beer, N du Plessis N du Plessis

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Discovery of a novel site regulating glucokinase activity following characterization of a new mutation causing hyperinsulinemic hypoglycemia in humans. by Beer, N, van de Bunt, M, Colclough, K, Lukacs, C, Arundel, P, Chik, C, Grimsby, J, Ellard, S, Gloyn, A

Insights into islet development and biology through characterization of a human iPSC-derived endocrine pancreas model by van de Bunt, M, Lako, M, Barrett, A, Gloyn, A, Hansson, M, McCarthy, M, Beer, N, Honoré, C

Genes associated with pancreas development and function maintain open chromatin in iPSCs generated from human pancreatic beta cells. by Thurner, M, Shenhav, L, Wesolowska-Andersen, A, Bennett, A, Barrett, A, Gloyn, A, McCarthy, M, Beer, N, Efrat, S

Insights into glucokinase regulatory protein regulation from the cellular and kinetic characterisation of rare coding variants by Rees, MG, Turner, C, Facio, F, Beer, N, McCarthy, M, Biesecker, L, Gloyn, A, Collins, F, Progra, N

Patterns of differential gene expression in a cellular model of human islet development, and relationship to type 2 diabetes predisposition by Perez-Alcantara, M, Honoré, C, Wesolowska-Andersen, A, Gloyn, A, McCarthy, M, Hansson, M, Beer, N, van de Bunt, M