Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase. by Hast, M, Fletcher, S, Cummings, C, Pusateri, E, Blaskovich, M, Rivas, K, Gelb, M, Van Voorhis, W, Sebti, S, Hamilton, A, Beese, L

Structure-based design and synthesis of potent, ethylenediamine-based, mammalian farnesyltransferase inhibitors as anticancer agents. by Fletcher, S, Keaney, E, Cummings, C, Blaskovich, M, Hast, M, Glenn, M, Chang, S, Bucher, C, Floyd, R, Katt, W, Gelb, M, Van Voorhis, W, Beese, L, Sebti, S, Hamilton, A