Functional analysis of a gene-edited mouse to gain insights into the disease mechanisms of a titin missense variant by Jiang, H, Hooper, C, Kelly, M, Steeples, V, Simon, J, Beglova, J, Azad, AJ, Leinhos, L, Bennett, P, Ehler, E, Kalisch-Smith, J, Sparrow, D, Fischer, R, Heilig, R, Isackson, H, Ehsan, M, Patone, G, Huebner, N, Davies, B, Watkins, H, Gehmlich, K