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Hybridization Kinetics Explains CRISPR-Cas Off-Targeting Rules by Misha Klein, Behrouz Eslami-Mossallam, Dylan Gonzalez Arroyo, Martin Depken
Published 2018-02-01
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A kinetic model predicts SpCas9 activity, improves off-target classification, and reveals the physical basis of targeting fidelity by Behrouz Eslami-Mossallam, Misha Klein, Constantijn V. D. Smagt, Koen V. D. Sanden, Stephen K. Jones, John A. Hawkins, Ilya J. Finkelstein, Martin Depken
Published 2022-03-01
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