Substrate reduction therapy for inborn errors of metabolism ‌ Yue, WW, Mackinnon, S, Arruda Bezerra, G

Bacterial protease uses distinct thermodynamic signatures for substrate recognition. ‌ Bezerra, G, Ohara-Nemoto, Y, Cornaciu, I, Fedosyuk, S, Hoffmann, G, Round, A, Márquez, J, Nemoto, T, Djinović-Carugo, K

Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III ‌ Arruda Bezerra, G, Dobrovetsky, E, Viertlmayr, R, Dong, A, Binter, A, Abramić, M, Macheroux, P, Dhe-Paganon, S, Gruber, K

Vaccinia virus immunomodulator A46: A lipid and protein-binding scaffold for sequestering host TIR-domain proteins. ‌ Fedosyuk, S, Bezerra, G, Radakovics, K, Smith, T, Sammito, M, Bobik, N, Round, A, Ten Eyck, L, Djinović-Carugo, K, Usón, I, Skern, T

Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism ‌ Arruda Bezerra, G, Foster, WR, Bailey, HJ, Hicks, KG, Sauer, SW, Dimitrov, B, McCorvie, TJ, Okun, JG, Rutter, J, Kölker, S, Yue, WW

Human aminolevulinate synthase structure reveals a eukaryotic-specific autoinhibitory loop regulating substrate binding and product release ‌ Bailey, HJ, Arruda Bezerra, G, Marcero, JR, Padhi, S, Foster, WR, Rembeza, E, Roy, A, Bishop, DF, Desnick, RJ, Bulusu, G, Dailey, HA, Yue, WW

Fragment screening reveals starting points for rational design of galactokinase 1 inhibitors to treat classic galactosemia ‌ Mackinnon, SR, Krojer, T, Foster, WR, Diaz-Saez, L, Tang, M, Huber, KVM, von Delft, F, Lai, K, Brennan, PE, Arruda Bezerra, G, Yue, WW