Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria. by Biagini, G, Fisher, N, Shone, A, Mubaraki, M, Srivastava, A, Hill, A, Antoine, T, Warman, A, Davies, J, Pidathala, C, Amewu, R, Leung, S, Sharma, R, Gibbons, P, Hong, D, Pacorel, B, Lawrenson, A, Charoensutthivarakul, S, Taylor, L, Berger, O, Mbekeani, A, Stocks, P, Nixon, G, Chadwick, J, Hemingway, J

A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance. by O'Neill, P, Amewu, R, Charman, S, Sabbani, S, Gnädig, N, Straimer, J, Fidock, D, Shore, E, Roberts, N, Wong, M, Hong, W, Pidathala, C, Riley, C, Murphy, B, Aljayyoussi, G, Gamo, F, Sanz, L, Rodrigues, J, Cortes, C, Herreros, E, Angulo-Barturén, I, Jiménez-Díaz, M, Bazaga, S, Martínez-Martínez, M, Campo, B, Sharma, R, Ryan, E, Shackleford, D, Campbell, S, Smith, D, Wirjanata, G, Noviyanti, R, Price, R, Marfurt, J, Palmer, M, Copple, I, Mercer, A, Ruecker, A, Delves, M, Sinden, R, Siegl, P, Davies, J, Rochford, R, Kocken, C, Zeeman, A, Nixon, G, Biagini, G, Ward, S