Genetic Interactions of STAT3 and Anticancer Drug Development by Bingliang Fang

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Differential Expression of Viral Transcripts From Single-Cell RNA Sequencing of Moderate and Severe COVID-19 Patients and Its Implications for Case Severity by Teng Liu, Peilin Jia, Bingliang Fang, Bingliang Fang, Zhongming Zhao, Zhongming Zhao, Zhongming Zhao

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Immunotherapy for non-small cell lung cancers: biomarkers for predicting responses and strategies to overcome resistance by Xingxiang Pu, Lin Wu, Dan Su, Weimin Mao, Bingliang Fang

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CombPDX: a unified statistical framework for evaluating drug synergism in patient-derived xenografts by Licai Huang, Jing Wang, Bingliang Fang, Funda Meric-Bernstam, Jack A. Roth, Min Jin Ha

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Accelerated Degradation of Caspase-8 Protein Correlates with TRAIL Resistance in a DLD1 Human Colon Cancer Cell Line by Lidong Zhang, Hongbo Zhu, Fuminori Teraishi, John J. Davis, Wei Guo, Zhen Fan, Bingliang Fang

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The tumor suppressor gene TUSC2 (FUS1) sensitizes NSCLC to the AKT inhibitor MK2206 in LKB1-dependent manner. by Jieru Meng, Mourad Majidi, Bingliang Fang, Lin Ji, B Nebiyou Bekele, John D Minna, Jack A Roth

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Antitumor activity of a novel oncrasin analogue is mediated by JNK activation and STAT3 inhibition. by Wei Guo, Shuhong Wu, Li Wang, Xiaoli Wei, Xiaoying Liu, Ji Wang, Zhimin Lu, Melinda Hollingshead, Bingliang Fang

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KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition by Pranavi Koppula, Kellen Olszewski, Yilei Zhang, Lavanya Kondiparthi, Xiaoguang Liu, Guang Lei, Molina Das, Bingliang Fang, Masha V. Poyurovsky, Boyi Gan

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Combination treatment with MEK and AKT inhibitors is more effective than each drug alone in human non-small cell lung cancer in vitro and in vivo. by Jieru Meng, Bingbing Dai, Bingliang Fang, B Nebiyou Bekele, William G Bornmann, Duoli Sun, Zhenghong Peng, Roy S Herbst, Vassiliki Papadimitrakopoulou, John D Minna, Michael Peyton, Jack A Roth

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The role of PKR/eIF2α signaling pathway in prognosis of non-small cell lung cancer. by Yong He, Arlene M Correa, Maria Gabriela Raso, Wayne L Hofstetter, Bingliang Fang, Carmen Behrens, Jack A Roth, Yihong Zhou, Liping Yu, Ignacio I Wistuba, Stephen G Swisher, Apar Pataer

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Downregulation of IFNG in CD4(+) T cells in lung cancer through hypermethylation: a possible mechanism of tumor-induced immunosuppression. by Fang Wang, Jian Xu, Quan Zhu, Xuejun Qin, Yan Cao, Jiangfang Lou, Yuqiao Xu, Xing Ke, Qing Li, Erfu Xie, Lixia Zhang, Ruihong Sun, Liang Chen, Bingliang Fang, Shiyang Pan

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Overcoming resistance to anti-PD immunotherapy in a syngeneic mouse lung cancer model using locoregional virotherapy by Xiang Yan, Li Wang, Ran Zhang, Xingxiang Pu, Shuhong Wu, Lili Yu, Ismail M. Meraz, Xiaoshan Zhang, Jacqueline F. Wang, Don L. Gibbons, Reza J. Mehran, Stephen G. Swisher, Jack A. Roth, Bingliang Fang

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Insulin-like growth factor binding protein-2 level is increased in blood of lung cancer patients and associated with poor survival. by Chengcheng Guo, Haibo Lu, Wen Gao, Li Wang, Kaihua Lu, Shuhong Wu, Apar Pataer, Maosheng Huang, Randa El-Zein, Tongyu Lin, Jack A Roth, Reza Mehran, Wayne Hofstetter, Stephen G Swisher, Xifeng Wu, Bingliang Fang

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Patient-derived tumor immune microenvironments in patient-derived xenografts of lung cancer by Xingxiang Pu, Ran Zhang, Li Wang, Yungchang Chen, Yi Xu, Apar Pataer, Ismail M. Meraz, Xiaoshan Zhang, Shuhong Wu, Lin Wu, Dan Su, Weimin Mao, John V. Heymach, Jack A. Roth, Stephen G. Swisher, Bingliang Fang

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mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation by Yilei Zhang, Robert V. Swanda, Litong Nie, Xiaoguang Liu, Chao Wang, Hyemin Lee, Guang Lei, Chao Mao, Pranavi Koppula, Weijie Cheng, Jie Zhang, Zhenna Xiao, Li Zhuang, Bingliang Fang, Junjie Chen, Shu-Bing Qian, Boyi Gan

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Aberrant expression of proteins involved in signal transduction and DNA repair pathways in lung cancer and their association with clinical parameters. by Yong He, Zhen Zhou, Wayne L Hofstetter, Yanbin Zhou, Wenxian Hu, Chengcheng Guo, Li Wang, Wei Guo, Apar Pataer, Arlene M Correa, Yiling Lu, Jing Wang, Lixia Diao, Lauren Averett Byers, Ignacio I Wistuba, Jack A Roth, Stephen G Swisher, John V Heymach, Bingliang Fang

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3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib by Ismail M. Meraz, Mourad Majidi, Bingliang Fang, Feng Meng, Lihui Gao, RuPing Shao, Renduo Song, Feng Li, Yonathan Lissanu, Huiqin Chen, Min Jin Ha, Qi Wang, Jing Wang, Elizabeth Shpall, Sung Yun Jung, Franziska Haderk, Philippe Gui, Jonathan Wesley Riess, Victor Olivas, Trever G. Bivona, Jack A. Roth

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Author Correction: 3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib by Ismail M. Meraz, Mourad Majidi, Bingliang Fang, Feng Meng, Lihui Gao, RuPing Shao, Renduo Song, Feng Li, Yonathan Lissanu, Huiqin Chen, Min Jin Ha, Qi Wang, Jing Wang, Elizabeth Shpall, Sung Yun Jung, Franziska Haderk, Philippe Gui, Jonathan Wesley Riess, Victor Olivas, Trever G. Bivona, Jack A. Roth

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Author Correction: Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment by Hua Sun, Song Cao, R. Jay Mashl, Chia-Kuei Mo, Simone Zaccaria, Michael C. Wendl, Sherri R. Davies, Matthew H. Bailey, Tina M. Primeau, Jeremy Hoog, Jacqueline L. Mudd, Dennis A. Dean, Rajesh Patidar, Li Chen, Matthew A. Wyczalkowski, Reyka G. Jayasinghe, Fernanda Martins Rodrigues, Nadezhda V. Terekhanova, Yize Li, Kian-Huat Lim, Andrea Wang-Gillam, Brian A. Van Tine, Cynthia X. Ma, Rebecca Aft, Katherine C. Fuh, Julie K. Schwarz, Jose P. Zevallos, Sidharth V. Puram, John F. Dipersio, The NCI PDXNet Consortium, Brandi Davis-Dusenbery, Matthew J. Ellis, Michael T. Lewis, Michael A. Davies, Meenhard Herlyn, Bingliang Fang, Jack A. Roth, Alana L. Welm, Bryan E. Welm, Funda Meric-Bernstam, Feng Chen, Ryan C. Fields, Shunqiang Li, Ramaswamy Govindan, James H. Doroshow, Jeffrey A. Moscow, Yvonne A. Evrard, Jeffrey H. Chuang, Benjamin J. Raphael, Li Ding

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Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment by Hua Sun, Song Cao, R. Jay Mashl, Chia-Kuei Mo, Simone Zaccaria, Michael C. Wendl, Sherri R. Davies, Matthew H. Bailey, Tina M. Primeau, Jeremy Hoog, Jacqueline L. Mudd, Dennis A. Dean, Rajesh Patidar, Li Chen, Matthew A. Wyczalkowski, Reyka G. Jayasinghe, Fernanda Martins Rodrigues, Nadezhda V. Terekhanova, Yize Li, Kian-Huat Lim, Andrea Wang-Gillam, Brian A. Van Tine, Cynthia X. Ma, Rebecca Aft, Katherine C. Fuh, Julie K. Schwarz, Jose P. Zevallos, Sidharth V. Puram, John F. Dipersio, The NCI PDXNet Consortium, Brandi Davis-Dusenbery, Matthew J. Ellis, Michael T. Lewis, Michael A. Davies, Meenhard Herlyn, Bingliang Fang, Jack A. Roth, Alana L. Welm, Bryan E. Welm, Funda Meric-Bernstam, Feng Chen, Ryan C. Fields, Shunqiang Li, Ramaswamy Govindan, James H. Doroshow, Jeffrey A. Moscow, Yvonne A. Evrard, Jeffrey H. Chuang, Benjamin J. Raphael, Li Ding

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