Discovery of rare variants via sequencing: implications for the design of complex trait association studies. by Bingshan Li, Suzanne M Leal

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Leveraging Gene-Level Prediction as Informative Covariate in Hypothesis Weighting Improves Power for Rare Variant Association Studies by Ying Ji, Rui Chen, Quan Wang, Qiang Wei, Ran Tao, Bingshan Li

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Integration of multidimensional splicing data and GWAS summary statistics for risk gene discovery. by Ying Ji, Qiang Wei, Rui Chen, Quan Wang, Ran Tao, Bingshan Li

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Drug repurposing for Alzheimer’s disease from 2012–2022—a 10-year literature review by Monika E. Grabowska, Annabelle Huang, Zhexing Wen, Bingshan Li, Wei-Qi Wei

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A Bayesian framework to integrate multi-level genome-scale data for Autism risk gene prioritization by Ying Ji, Rui Chen, Quan Wang, Qiang Wei, Ran Tao, Bingshan Li

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Incidental Pulmonary Metastases Revealing Subcentimeter Papillary Thyroid Carcinoma by Ruey Hu, MD, MPH, George Xu, Thomas Stricker, MD, PhD, Bingshan Li, PhD, Vivian L. Weiss, MD, PhD, Lindsay Bischoff, MD

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Integration of circulating tumor cell and neutrophil-lymphocyte ratio to identify high-risk metastatic castration-resistant prostate cancer patients by Weelic Chong, Zhenchao Zhang, Rui Luo, Jian Gu, Jianqing Lin, Qiang Wei, Bingshan Li, Ronald Myers, Grace Lu-Yao, William Kevin Kelly, Chun Wang, Hushan Yang

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Improved Prognostic Stratification Using Circulating Tumor Cell Clusters in Patients with Metastatic Castration-Resistant Prostate Cancer by Chun Wang, Zhenchao Zhang, Weelic Chong, Rui Luo, Ronald E. Myers, Jian Gu, Jianqing Lin, Qiang Wei, Bingshan Li, Timothy R. Rebbeck, Grace Lu-Yao, William K. Kelly, Hushan Yang

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Whole-exome sequencing identifies somatic mutations and intratumor heterogeneity in inflammatory breast cancer by Rui Luo, Weelic Chong, Qiang Wei, Zhenchao Zhang, Chun Wang, Zhong Ye, Maysa M. Abu-Khalaf, Daniel P. Silver, Robert T. Stapp, Wei Jiang, Ronald E. Myers, Bingshan Li, Massimo Cristofanilli, Hushan Yang

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Leveraging generative AI to prioritize drug repurposing candidates for Alzheimer’s disease with real-world clinical validation by Chao Yan, Monika E. Grabowska, Alyson L. Dickson, Bingshan Li, Zhexing Wen, Dan M. Roden, C. Michael Stein, Peter J. Embí, Josh F. Peterson, QiPing Feng, Bradley A. Malin, Wei-Qi Wei

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Genomic Aberrations in Circulating Tumor DNAs from Palbociclib-Treated Metastatic Breast Cancer Patients Reveal a Novel Resistance Mechanism by Maysa Abu-Khalaf, Chun Wang, Zhenchao Zhang, Rui Luo, Weelic Chong, Daniel P. Silver, Frederick Fellin, Rebecca Jaslow, AnaMaria Lopez, Terrence Cescon, Wei Jiang, Ronald Myers, Qiang Wei, Bingshan Li, Massimo Cristofanilli, Hushan Yang

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Multi-ancestry and multi-trait genome-wide association meta-analyses inform clinical risk prediction for systemic lupus erythematosus by Chachrit Khunsriraksakul, Qinmengge Li, Havell Markus, Matthew T. Patrick, Renan Sauteraud, Daniel McGuire, Xingyan Wang, Chen Wang, Lida Wang, Siyuan Chen, Ganesh Shenoy, Bingshan Li, Xue Zhong, Nancy J. Olsen, Laura Carrel, Lam C. Tsoi, Bibo Jiang, Dajiang J. Liu

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Recurrent tissue-specific mtDNA mutations are common in humans. by David C Samuels, Chun Li, Bingshan Li, Zhuo Song, Eric Torstenson, Hayley Boyd Clay, Antonis Rokas, Tricia A Thornton-Wells, Jason H Moore, Tia M Hughes, Robert D Hoffman, Jonathan L Haines, Deborah G Murdock, Douglas P Mortlock, Scott M Williams

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A big-data approach to understanding metabolic rate and response to obesity in laboratory mice by June K Corrigan, Deepti Ramachandran, Yuchen He, Colin J Palmer, Michael J Jurczak, Rui Chen, Bingshan Li, Randall H Friedline, Jason K Kim, Jon J Ramsey, Louise Lantier, Owen P McGuinness, Mouse Metabolic Phenotyping Center Energy Balance Working Group, Alexander S Banks

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Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability. by Serena Sanna, Bingshan Li, Antonella Mulas, Carlo Sidore, Hyun M Kang, Anne U Jackson, Maria Grazia Piras, Gianluca Usala, Giuseppe Maninchedda, Alessandro Sassu, Fabrizio Serra, Maria Antonietta Palmas, William H Wood, Inger Njølstad, Markku Laakso, Kristian Hveem, Jaakko Tuomilehto, Timo A Lakka, Rainer Rauramaa, Michael Boehnke, Francesco Cucca, Manuela Uda, David Schlessinger, Ramaiah Nagaraja, Gonçalo R Abecasis

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Erratum: A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling by Dong Li, Xiao Chang, John J. Connolly, Lifeng Tian, Yichuan Liu, Elizabeth J. Bhoj, Nora Robinson, Debra Abrams, Yun R. Li, Jonathan P. Bradfield, Cecilia E. Kim, Jin Li, Fengxiang Wang, James Snyder, Maria Lemma, Cuiping Hou, Zhi Wei, Yiran Guo, Haijun Qiu, Frank D. Mentch, Kelly A. Thomas, Rosetta M. Chiavacci, Roger Cone, Bingshan Li, Patrick A. Sleiman, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Price Foundation Collaborative Group, Hakon Hakonarson

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A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling by Dong Li, Xiao Chang, John J. Connolly, Lifeng Tian, Yichuan Liu, Elizabeth J. Bhoj, Nora Robinson, Debra Abrams, Yun R. Li, Jonathan P. Bradfield, Cecilia E. Kim, Jin Li, Fengxiang Wang, James Snyder, Maria Lemma, Cuiping Hou, Zhi Wei, Yiran Guo, Haijun Qiu, Frank D. Mentch, Kelly A. Thomas, Rosetta M. Chiavacci, Roger Cone, Bingshan Li, Patrick A. Sleiman, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Price Foundation Collaborative Group, Hakon Hakonarson

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Genome sequencing unveils a regulatory landscape of platelet reactivity by Ali R. Keramati, Ming-Huei Chen, Benjamin A. T. Rodriguez, Lisa R. Yanek, Arunoday Bhan, Brady J. Gaynor, Kathleen Ryan, Jennifer A. Brody, Xue Zhong, Qiang Wei, NHLBI Trans-Omics for Precision (TOPMed) Consortium, Kai Kammers, Kanika Kanchan, Kruthika Iyer, Madeline H. Kowalski, Achilleas N. Pitsillides, L. Adrienne Cupples, Bingshan Li, Thorsten M. Schlaeger, Alan R. Shuldiner, Jeffrey R. O’Connell, Ingo Ruczinski, Braxton D. Mitchell, Nauder Faraday, Margaret A. Taub, Lewis C. Becker, Joshua P. Lewis, Rasika A. Mathias, Andrew D. Johnson

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Molecular signature incorporating the immune microenvironment enhances thyroid cancer outcome prediction by George J. Xu, Matthew A. Loberg, Jean-Nicolas Gallant, Quanhu Sheng, Sheau-Chiann Chen, Brian D. Lehmann, Sophia M. Shaddy, Megan L. Tigue, Courtney J. Phifer, Li Wang, Mario W. Saab-Chalhoub, Lauren M. Dehan, Qiang Wei, Rui Chen, Bingshan Li, Christine Y. Kim, Donna C. Ferguson, James L. Netterville, Sarah L. Rohde, Carmen C. Solórzano, Lindsay A. Bischoff, Naira Baregamian, Aaron C. Shaver, Mitra Mehrad, Kim A. Ely, Daniel W. Byrne, Thomas P. Stricker, Barbara A. Murphy, Jennifer H. Choe, Luciane T. Kagohara, Elizabeth M. Jaffee, Eric C. Huang, Fei Ye, Ethan Lee, Vivian L. Weiss

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Re-evaluating genetic variants identified in candidate gene studies of breast cancer risk using data from nearly 280,000 women of Asian and European ancestryResearch in context by Yaohua Yang, Xiang Shu, Xiao-ou Shu, Manjeet K. Bolla, Sun-Seog Kweon, Qiuyin Cai, Kyriaki Michailidou, Qin Wang, Joe Dennis, Boyoung Park, Keitaro Matsuo, Ava Kwong, Sue Kyung Park, Anna H. Wu, Soo Hwang Teo, Motoki Iwasaki, Ji-Yeob Choi, Jingmei Li, Mikael Hartman, Chen-Yang Shen, Kenneth Muir, Artitaya Lophatananon, Bingshan Li, Wanqing Wen, Yu-Tang Gao, Yong-Bing Xiang, Kristan J. Aronson, John J. Spinell, Manuela Gago-Dominguez, Esther M. John, Allison W. Kurian, Jenny Chang-Claude, Shou-Tung Chen, Thilo Dörk, D. Gareth R. Evans, Marjanka K. Schmidt, Min-Ho Shin, Graham G. Giles, Roger L. Milne, Jacques Simard, Michiaki Kubo, Peter Kraft, Daehee Kang, Douglas F. Easton, Wei Zheng, Jirong Long

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