Discovery of rare variants via sequencing: implications for the design of complex trait association studies. by Bingshan Li, Suzanne M Leal

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Integration of multidimensional splicing data and GWAS summary statistics for risk gene discovery. by Ying Ji, Qiang Wei, Rui Chen, Quan Wang, Ran Tao, Bingshan Li

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Drug repurposing for Alzheimer’s disease from 2012–2022—a 10-year literature review by Monika E. Grabowska, Annabelle Huang, Zhexing Wen, Bingshan Li, Wei-Qi Wei

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A Bayesian framework to integrate multi-level genome-scale data for Autism risk gene prioritization by Ying Ji, Rui Chen, Quan Wang, Qiang Wei, Ran Tao, Bingshan Li

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Leveraging Identity-by-Descent for Accurate Genotype Inference in Family Sequencing Data. by Bingshan Li, Qiang Wei, Xiaowei Zhan, Xue Zhong, Wei Chen, Chun Li, Jonathan Haines

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PSCAN: Spatial scan tests guided by protein structures improve complex disease gene discovery and signal variant detection by Zheng-Zheng Tang, Gregory R. Sliwoski, Guanhua Chen, Bowen Jin, William S. Bush, Bingshan Li, John A. Capra

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A likelihood-based framework for variant calling and de novo mutation detection in families. by Bingshan Li, Wei Chen, Xiaowei Zhan, Fabio Busonero, Serena Sanna, Carlo Sidore, Francesco Cucca, Hyun M Kang, Gonçalo R Abecasis

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Genetic polymorphism in a VEGF-independent angiogenesis gene ANGPT1 and overall survival of colorectal cancer patients after surgical resection. by Jingyao Dai, Shaogui Wan, Feng Zhou, Ronald E Myers, Xu Guo, Bingshan Li, Xiaoying Fu, Juan P Palazzo, Kefeng Dou, Hushan Yang, Jinliang Xing

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Incidental Pulmonary Metastases Revealing Subcentimeter Papillary Thyroid Carcinoma by Ruey Hu, MD, MPH, George Xu, Thomas Stricker, MD, PhD, Bingshan Li, PhD, Vivian L. Weiss, MD, PhD, Lindsay Bischoff, MD

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Integration of circulating tumor cell and neutrophil-lymphocyte ratio to identify high-risk metastatic castration-resistant prostate cancer patients by Weelic Chong, Zhenchao Zhang, Rui Luo, Jian Gu, Jianqing Lin, Qiang Wei, Bingshan Li, Ronald Myers, Grace Lu-Yao, William Kevin Kelly, Chun Wang, Hushan Yang

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Integrating electronic health records and GWAS summary statistics to predict the progression of autoimmune diseases from preclinical stages by Chen Wang, Havell Markus, Avantika R. Diwadkar, Chachrit Khunsriraksakul, Laura Carrel, Bingshan Li, Xue Zhong, Xingyan Wang, Xiaowei Zhan, Galen T. Foulke, Nancy J. Olsen, Dajiang J. Liu, Bibo Jiang

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DRAMS: A tool to detect and re-align mixed-up samples for integrative studies of multi-omics data. by Yi Jiang, Gina Giase, Kay Grennan, Annie W Shieh, Yan Xia, Lide Han, Quan Wang, Qiang Wei, Rui Chen, Sihan Liu, Kevin P White, Chao Chen, Bingshan Li, Chunyu Liu

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Whole-exome sequencing identifies somatic mutations and intratumor heterogeneity in inflammatory breast cancer by Rui Luo, Weelic Chong, Qiang Wei, Zhenchao Zhang, Chun Wang, Zhong Ye, Maysa M. Abu-Khalaf, Daniel P. Silver, Robert T. Stapp, Wei Jiang, Ronald E. Myers, Bingshan Li, Massimo Cristofanilli, Hushan Yang

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Leveraging generative AI to prioritize drug repurposing candidates for Alzheimer’s disease with real-world clinical validation by Chao Yan, Monika E. Grabowska, Alyson L. Dickson, Bingshan Li, Zhexing Wen, Dan M. Roden, C. Michael Stein, Peter J. Embí, Josh F. Peterson, QiPing Feng, Bradley A. Malin, Wei-Qi Wei

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Multi-ancestry and multi-trait genome-wide association meta-analyses inform clinical risk prediction for systemic lupus erythematosus by Chachrit Khunsriraksakul, Qinmengge Li, Havell Markus, Matthew T. Patrick, Renan Sauteraud, Daniel McGuire, Xingyan Wang, Chen Wang, Lida Wang, Siyuan Chen, Ganesh Shenoy, Bingshan Li, Xue Zhong, Nancy J. Olsen, Laura Carrel, Lam C. Tsoi, Bibo Jiang, Dajiang J. Liu

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Recurrent tissue-specific mtDNA mutations are common in humans. by David C Samuels, Chun Li, Bingshan Li, Zhuo Song, Eric Torstenson, Hayley Boyd Clay, Antonis Rokas, Tricia A Thornton-Wells, Jason H Moore, Tia M Hughes, Robert D Hoffman, Jonathan L Haines, Deborah G Murdock, Douglas P Mortlock, Scott M Williams

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A big-data approach to understanding metabolic rate and response to obesity in laboratory mice by June K Corrigan, Deepti Ramachandran, Yuchen He, Colin J Palmer, Michael J Jurczak, Rui Chen, Bingshan Li, Randall H Friedline, Jason K Kim, Jon J Ramsey, Louise Lantier, Owen P McGuinness, Mouse Metabolic Phenotyping Center Energy Balance Working Group, Alexander S Banks

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Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability. by Serena Sanna, Bingshan Li, Antonella Mulas, Carlo Sidore, Hyun M Kang, Anne U Jackson, Maria Grazia Piras, Gianluca Usala, Giuseppe Maninchedda, Alessandro Sassu, Fabrizio Serra, Maria Antonietta Palmas, William H Wood, Inger Njølstad, Markku Laakso, Kristian Hveem, Jaakko Tuomilehto, Timo A Lakka, Rainer Rauramaa, Michael Boehnke, Francesco Cucca, Manuela Uda, David Schlessinger, Ramaiah Nagaraja, Gonçalo R Abecasis

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Erratum: A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling by Dong Li, Xiao Chang, John J. Connolly, Lifeng Tian, Yichuan Liu, Elizabeth J. Bhoj, Nora Robinson, Debra Abrams, Yun R. Li, Jonathan P. Bradfield, Cecilia E. Kim, Jin Li, Fengxiang Wang, James Snyder, Maria Lemma, Cuiping Hou, Zhi Wei, Yiran Guo, Haijun Qiu, Frank D. Mentch, Kelly A. Thomas, Rosetta M. Chiavacci, Roger Cone, Bingshan Li, Patrick A. Sleiman, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Price Foundation Collaborative Group, Hakon Hakonarson

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An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk by Lang Wu, Yaohua Yang, Xingyi Guo, Xiao-Ou Shu, Qiuyin Cai, Xiang Shu, Bingshan Li, Ran Tao, Chong Wu, Jason B. Nikas, Yanfa Sun, Jingjing Zhu, Monique J. Roobol, Graham G. Giles, Hermann Brenner, Esther M. John, Judith Clements, Eli Marie Grindedal, Jong Y. Park, Janet L. Stanford, Zsofia Kote-Jarai, Christopher A. Haiman, Rosalind A. Eeles, Wei Zheng, Jirong Long, The PRACTICAL consortium, CRUK Consortium, BPC3 Consortium, CAPS Consortium, PEGASUS Consortium

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