Editorial: Women in molecular innate immunity by Francesca Granucci, Laura Marongiu, Birgit Strobl

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Metabolic Regulators Nampt and Sirt6 Serially Participate in the Macrophage Interferon Antiviral Cascade by Widad Dantoft, Kevin A. Robertson, W. John Watkins, Birgit Strobl, Peter Ghazal, Peter Ghazal

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From Science to Success? Targeting Tyrosine Kinase 2 in Spondyloarthritis and Related Chronic Inflammatory Diseases by Dominika Hromadová, Dirk Elewaut, Dirk Elewaut, Robert D. Inman, Robert D. Inman, Birgit Strobl, Eric Gracey, Eric Gracey

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In vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity by Michaela Prchal-Murphy, Agnieszka Witalisz-Siepracka, Karoline T Bednarik, Eva Maria Putz, Dagmar Gotthardt, Katrin Meissl, Veronika Sexl, Mathias Müller, Birgit Strobl

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Lack of TYK2 signaling enhances host resistance to Candida albicans skin infection by Sara Miranda, Caroline Lassnig, Kristina Schmidhofer, Hrönn Kjartansdottir, Claus Vogl, Simone Tangermann, Irina Tsymala, Verena Babl, Mathias Müller, Karl Kuchler, Birgit Strobl

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The C-Terminal Transactivation Domain of STAT1 Has a Gene-Specific Role in Transactivation and Cofactor Recruitment by Matthias Parrini, Katrin Meissl, Mojoyinola Joanna Ola, Therese Lederer, Ana Puga, Sebastian Wienerroither, Pavel Kovarik, Thomas Decker, Mathias Müller, Mathias Müller, Birgit Strobl

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Cooperative Transcriptional Activation of Antimicrobial Genes by STAT and NF-κB Pathways by Concerted Recruitment of the Mediator Complex by Sebastian Wienerroither, Priyank Shukla, Matthias Farlik, Andrea Majoros, Bernadette Stych, Claus Vogl, HyeonJoo Cheon, George R. Stark, Birgit Strobl, Mathias Müller, Thomas Decker

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Conditional Stat1 ablation reveals the importance of interferon signaling for immunity to Listeria monocytogenes infection. by Elisabeth Kernbauer, Verena Maier, Dagmar Stoiber, Birgit Strobl, Christine Schneckenleithner, Veronika Sexl, Ursula Reichart, Boris Reizis, Ulrich Kalinke, Amanda Jamieson, Mathias Müller, Thomas Decker

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Inducible, dose-adjustable and time-restricted reconstitution of STAT1 deficiency in vivo. by Nicole R Leitner, Caroline Lassnig, Rita Rom, Susanne Heider, Zsuzsanna Bago-Horvath, Robert Eferl, Simone Müller, Thomas Kolbe, Lukas Kenner, Thomas Rülicke, Birgit Strobl, Mathias Müller

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Bacterial polyphosphates interfere with the innate host defense to infection by Julian Roewe, Georgios Stavrides, Marcel Strueve, Arjun Sharma, Federico Marini, Amrit Mann, Stephanie A. Smith, Ziya Kaya, Birgit Strobl, Mathias Mueller, Christoph Reinhardt, James H. Morrissey, Markus Bosmann

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Single-cell transcriptional profiling of splenic fibroblasts reveals subset-specific innate immune signatures in homeostasis and during viral infection by Joern Pezoldt, Carolin Wiechers, Florian Erhard, Ulfert Rand, Tanja Bulat, Michael Beckstette, Andrea Brendolan, Jochen Huehn, Ulrich Kalinke, Mathias Mueller, Birgit Strobl, Bart Deplancke, Luka Čičin-Šain, Katarzyna M. Sitnik

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T-Bet Controls Cellularity of Intestinal Group 3 Innate Lymphoid Cells by Jan-Hendrik Schroeder, Katrin Meissl, Dominika Hromadová, Jonathan W. Lo, Jonathan W. Lo, Joana F. Neves, Jane K. Howard, Helena Helmby, Nick Powell, Birgit Strobl, Graham M. Lord, Graham M. Lord

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Tyk2 is a tumor suppressor in colorectal cancer by Stefan Moritsch, Bernadette Mödl, Irene Scharf, Lukas Janker, Daniela Zwolanek, Gerald Timelthaler, Emilio Casanova, Maria Sibilia, Thomas Mohr, Lukas Kenner, Dietmar Herndler-Brandstetter, Christopher Gerner, Mathias Müller, Birgit Strobl, Robert Eferl

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Lipocalin 2 modulates dendritic cell activity and shapes immunity to influenza in a microbiome dependent manner. by Martin L Watzenboeck, Barbara Drobits, Sophie Zahalka, Anna-Dorothea Gorki, Asma Farhat, Federica Quattrone, Anastasiya Hladik, Karin Lakovits, Gabriel M Richard, Therese Lederer, Birgit Strobl, Gijs A Versteeg, Louis Boon, Philipp Starkl, Sylvia Knapp

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STAT1 is a sex‐specific tumor suppressor in colitis‐associated colorectal cancer by Ilija Crnčec, Madhura Modak, Claire Gordziel, Jasmin Svinka, Irene Scharf, Stefan Moritsch, Paulina Pathria, Michaela Schlederer, Lukas Kenner, Gerald Timelthaler, Mathias Müller, Birgit Strobl, Emilio Casanova, Editha Bayer, Thomas Mohr, Johannes Stöckl, Karlheinz Friedrich, Robert Eferl

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STAT1 Isoforms Differentially Regulate NK Cell Maturation and Anti-tumor Activity by Katrin Meissl, Natalija Simonović, Lena Amenitsch, Agnieszka Witalisz-Siepracka, Agnieszka Witalisz-Siepracka, Klara Klein, Klara Klein, Caroline Lassnig, Caroline Lassnig, Ana Puga, Claus Vogl, Andrea Poelzl, Markus Bosmann, Markus Bosmann, Alexander Dohnal, Veronika Sexl, Mathias Müller, Mathias Müller, Birgit Strobl

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Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis. by Mathieu Blanc, Wei Yuan Hsieh, Kevin A Robertson, Steven Watterson, Guanghou Shui, Paul Lacaze, Mizanur Khondoker, Paul Dickinson, Garwin Sing, Sara Rodríguez-Martín, Peter Phelan, Thorsten Forster, Birgit Strobl, Matthias Müller, Rudolph Riemersma, Timothy Osborne, Markus R Wenk, Ana Angulo, Peter Ghazal

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Oncogenic TYK2 P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade by Katharina Woess, Sabine Macho-Maschler, Dorette S. van Ingen Schenau, Miriam Butler, Caroline Lassnig, Daniel Valcanover, Andrea Poelzl, Katrin Meissl, Barbara Maurer, Tania Brandstoetter, Claus Vogl, Anna Koren, Stefan Kubicek, Anna Orlova, Richard Moriggl, Birgit Strobl, Veronika Sexl, Frank N. van Leeuwen, Roland P. Kuiper, Mathias Mueller

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Sustained Post-Developmental T-Bet Expression Is Critical for the Maintenance of Type One Innate Lymphoid Cells In Vivo by Jan-Hendrik Schroeder, Luke B. Roberts, Katrin Meissl, Jonathan W. Lo, Jonathan W. Lo, Dominika Hromadová, Kelly Hayes, Tomasz Zabinski, Emily Read, Emily Read, Catarina Moreira Heliodoro, Rita Reis, Jane K. Howard, Richard K. Grencis, Joana F. Neves, Birgit Strobl, Graham M. Lord, Graham M. Lord

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JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression by Torben Redmer, Martin Raigel, Christina Sternberg, Roman Ziegler, Clara Probst, Desiree Lindner, Astrid Aufinger, Tanja Limberger, Karolina Trachtova, Petra Kodajova, Sandra Högler, Michaela Schlederer, Stefan Stoiber, Monika Oberhuber, Marco Bolis, Heidi A. Neubauer, Sara Miranda, Martina Tomberger, Nora S. Harbusch, Ines Garces de los Fayos Alonso, Felix Sternberg, Richard Moriggl, Jean-Philippe Theurillat, Boris Tichy, Vojtech Bystry, Jenny L. Persson, Stephan Mathas, Fritz Aberger, Birgit Strobl, Sarka Pospisilova, Olaf Merkel, Gerda Egger, Sabine Lagger, Lukas Kenner

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