MicroSCALE Screening Reveals Genetic Modifiers of Therapeutic Response in Melanoma ανά Wood, Kris C., Konieczkowski, David J., Johannessen, Cory M., Boehm, Jesse S., Tamayo, Pablo, Botvinnik, Olga B., Mesirov, Jill P., Hahn, William C., Root, David E., Garraway, Levi A., Sabatini, David

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Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood ανά Verdine, Vanessa K., Aguet, Francois, Fulco, Charles P., Tseng, Yuen-Yi, Boehm, Jesse S., Joung, Julia, Engreitz, Jesse Michael, Konermann, Silvana M, Gootenberg, Jonathan S, Sanjana, Neville E, Wright, Jason, Yoon, Charles, Lander, Eric Steven, Zhang, Feng, Abudayyeh, Omar O.

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PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment ανά Collins, Natalie B, Al Abosy, Rose, Miller, Brian C, Bi, Kevin, Zhao, Qihong, Quigley, Michael, Ishizuka, Jeffrey J, Yates, Kathleen B, Pope, Hans W, Manguso, Robert T, Shrestha, Yashaswi, Wadsworth, Marc, Hughes, Travis, Shalek, Alex K, Boehm, Jesse S, Hahn, William C, Doench, John G, Haining, W Nicholas

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Synthetic Lethal Interaction between Oncogenic KRAS Dependency and STK33 Suppression in Human Cancer Cells ανά Scholl, Claudia, Frohling, Stefan, Dunn, Ian F., Schinzel, Anna C., Barbie, David A., Kim, So Young, Silver, Serena J., Tamayo, Pablo, Wadlow, Raymond C., Ramaswamy, Sridhar, Dohner, Konstanze, Bullinger, Lars, Sandy, Peter, Boehm, Jesse S., Root, David E., Hahn, William C., Gilliland, D. Gary, Jacks, Tyler E

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Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development ανά Giannikou, Krinio, Malinowska, Izabela A., Pugh, Trevor J., Yan, Rachel, Tseng, Yuen-Yi, Kim, Jaegil, Tyburczy, Magdalena E., Chekaluk, Yvonne, Liu, Yang, Alesi, Nicola, Finlay, Geraldine A., Wu, Chin-Lee, Signoretti, Sabina, Henske, Elizabeth P., Kwiatkowski, David J., Oh, Coyin, Meyerson, Matthew L, Getz, Gad Asher, Boehm, Jesse S

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GeNets: a unified web platform for network-based genomic analyses ανά Li, Taibo, Kim, April, Rosenbluh, Joseph, Horn, Heiko, Greenfeld, Liraz, An, David, Zimmer, Andrew, Liberzon, Arthur, Bistline, Jon, Natoli, Ted, Li, Yang, Tsherniak, Aviad, Narayan, Rajiv, Subramanian, Aravind, Liefeld, Ted, Wong, Bang, Thompson, Dawn, Calvo, Sarah, Carr, Steve, Boehm, Jesse, Jaffe, Jake, Mesirov, Jill, Hacohen, Nir, Regev, Aviv, Lage, Kasper

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Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Target ID4 ανά Ren, Yin, von Maltzhan, Geoffrey, Agrawal, Amit, Mesirov, Jill P., Lo, Justin H., Cheung, Hiu Wing, Cowley, Glenn S., Weir, Barbara A., Boehm, Jesse S., Tamayo, Pablo, Karst, Alison M., Liu, Joyce F., Hirsch, Michelle S., Drapkin, Ronny, Root, David E., Fogal, Valentina, Ruoslahti, Erkki, Hahn, William C., Bhatia, Sangeeta N

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Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1 ανά Sandy, Peter, Meylan, Etienne, Reiling, Jan H., Hoersch, Sebastian, Barbie, David A., Tamayo, Pablo, Boehm, Jesse S., Kim, So Young, Moody, Susan E., Dunn, Ian F., Schinzel, Anna C., Scholl, Claudia, Frohling, Stefan, Chan, Edmond M., Sos, Martin L., Michel, Kathrin, Mermel, Craig H., Sabatini, David, Lander, Eric Steven, Jacks, Tyler E

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Recurrent and functional regulatory mutations in breast cancer ανά Parasuraman, Prasanna, Tiao, Grace, Kim, Jaegil, Taylor-Weiner, Amaro, Rodriguez-Cuevas, Sergio, Rosenberg, Mara, Hess, Julian, Stewart, Chip, Maruvka, Yosef E., Stojanov, Petar, Seepo, Sara, Cibulskis, Carrie, Tracy, Adam, Pugh, Trevor J., Lee, Jesse, Zheng, Zongli, Ellisen, Leif W., Iafrate, A. John, Boehm, Jesse S., Baselga, Jose, Hidalgo-Miranda, Alfredo, Shioda, Toshi, Bernards, Andre, Engreitz, Jesse Michael, Lander, Eric Steven, Rheinbay, Esther, Lawrence, Michael, Cortes, Maria, Gabriel, Stacey, Golub, Todd, Getz, Gad Asher, Meyerson, Matthew L.

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Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer ανά Ren, Yin, Meyerson, Matthew L., Drapkin, Ronny, Cheung, Hiu Wing, Cowley, Glenn S., Weir, Barbara A., Boehm, Jesse S., Rusin, Scott, Scott, Justine A., East, Alexandra, Ali, Levi D., Lizotte, Patrick H., Wong, Terence C., Jiang, Guozhi, Hsiao, Jessica, Mermel, Craig H., Getz, Gad, Barretina, Jordi, Gopal, Shuba, Tamayo, Pablo, Gould, Joshua, Tsherniak, Aviad, Stransky, Nicolas, Luo, Biao, Mesirov, Jill P., Garraway, Levi A., Lander, Eric S., Root, David E., Hahn, William C., Bhatia, Sangeeta N

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Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors ανά Ha, Gavin, Freeman, Samuel S., Choudhury, Atish D., Stover, Daniel G., Parsons, Heather A., Gydush, Gregory, Reed, Sarah C., Rotem, Denisse, Rhoades, Justin, Livitz, Dimitri, Rosebrock, Daniel, Leshchiner, Ignaty, Kim, Jaegil, Stewart, Chip, Rosenberg, Mara, Francis, Joshua M., Zhang, Cheng-Zhong, Cohen, Ofir, Oh, Coyin, Polak, Paz, Lloyd, Max, Mahmud, Sairah, Helvie, Karla, Merrill, Margaret S., Santiago, Rebecca A., O’Connor, Edward P., Jeong, Seong H., Kramkowski, Joseph F., Zhang, Zhenwei, Polacek, Laura, Lohr, Jens G., Schleicher, Molly, Lipscomb, Emily, Saltzman, Andrea, Oliver, Nelly M., Marini, Lori, Waks, Adrienne G., Harshman, Lauren C., Tolaney, Sara M., Van Allen, Eliezer M., Winer, Eric P., Lin, Nancy U., Nakabayashi, Mari, Taplin, Mary-Ellen, Johannessen, Cory M., Garraway, Levi A., Golub, Todd R., Boehm, Jesse S., Wagle, Nikhil, Getz, Gad, Meyerson, Matthew, Adalsteinsson, Viktor A., Loginov, Denis, Ding, Huiming, Leeson, Rachel, Barry, Rachel M, Love, John C

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