Comparing Power for Gene-based and Low-frequency SNP Tests in Quantitative Traits (a GoT2D Study) by Manning, A, Sim, X, Locke, A, Agarwala, V, Moutsianas, L, Weyant, R, McCarthy, M, Altshuler, D, Boehnke, M

A partial loss-of-function variant in AKT2 is associated with reduced insulin-mediated glucose uptake in multiple insulin sensitive tissues: a genotype-based callback positron emis... by Latva-Rasku, A, Honka, M, Stančáková, A, Koistinen, H, Kuusisto, J, Guan, L, Manning, A, Stringham, H, Gloyn, A, Lindgren, C, Collins, F, Mohlke, K, Scott, L, Karjalainen, T, Nummenmaa, L, Boehnke, M, Nuutila, P, Laakso, M

Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS by Pan, D, Garske, K, Alvarez, M, Bhagat, Y, Boocock, J, Nikkola, E, Miao, Z, Raulerson, C, Cantor, R, Civelek, M, Glastonbury, C, Small, K, Boehnke, M, Lusis, A, Sinsheimer, J, Mohlke, K, Laakso, M, Pajukanta, P, Ko, A

Novel Genetic Loci Implicated in Fasting Glucose Homeostasis and Their Impact on Related Metabolic Traits by Dupuis, J, Langenberg, C, Prokopenko, I, Saxena, R, Soranzo, N, Jackson, A, Wheeler, E, Glazer, N, Bouatia-Naji, N, McCullogh, L, Gloyn, A, Sladek, R, Froguel, P, Watanabe, R, Meigs, J, Groop, L, Boehnke, M, McCarthy, M, Florez, J, Barroso, I, Investigators, MAGIC

Search for novel type 2 diabetes susceptibility loci using genome-wide association studies imputed from a 1000 Genomes references panel by Prokopenko, I, Ma, C, Maegi, R, Chen, H, Voight, B, Qi, L, Van Zuydam, N, Grallert, H, Yengo, L, Dina, C, Thorleifsson, G, Fucshberger, C, Liang, L, Mueller-Nurasyi, M, Willems, S, Kao, L, Navarro, P, Steinthorsdottir, V, Boehnke, M, Dupuis, J, Mccarthy, M, Scott, L, Diagram, C

A role for coding functional variants in HNF4A in type 2 diabetes susceptibility by Jafar-Mohammadi, B, Groves, C, Gjesing, A, Herrera, B, Winckler, W, Stringham, H, Morris, A, Lauritzen, T, Doney, A, Morris, A, Weedon, M, Swift, A, Kuusisto, J, Laakso, M, Altshuler, D, Hattersley, A, Collins, F, Boehnke, M, Hansen, T, Pedersen, O, Palmer, C, Frayling, T, Gloyn, A, McCarthy, M

A role for coding functional variants in HNF4A in type 2 diabetes susceptibility. by Jafar-Mohammadi, B, Groves, C, Gjesing, A, Herrera, B, Winckler, W, Stringham, H, Morris, A, Lauritzen, T, Doney, A, Morris, A, Weedon, M, Swift, A, Kuusisto, J, Laakso, M, Altshuler, D, Hattersley, A, Collins, F, Boehnke, M, Hansen, T, Pedersen, O, Palmer, C, Frayling, T, Gloyn, A, McCarthy, M

Underlying genetic models of inheritance in established type 2 diabetes associations. by Salanti, G, Southam, L, Altshuler, D, Ardlie, K, Barroso, I, Boehnke, M, Cornelis, M, Frayling, T, Grallert, H, Grarup, N, Groop, L, Hansen, T, Hattersley, A, Hu, F, Hveem, K, Illig, T, Kuusisto, J, Laakso, M, Langenberg, C, Lyssenko, V, McCarthy, M, Morris, A, Morris, A, Palmer, C, Payne, F

Community assembly during secondary forest succession in a Chinese subtropical forest by Bruelheide, H, Boehnke, M, Both, S, Fang, T, Assmann, T, Baruffol, M, Bauhus, J, Buscot, F, Chen, X, Ding, B, Durka, W, Erfmeier, A, Fischer, M, Geissler, C, Guo, D, Guo, L, Haerdtle, W, He, J, Hector, A, Kroeber, W, Kuehn, P, Lang, A, Nadrowski, K, Pei, K, Scherer-Lorenzen, M

Finding the missing heritability of complex diseases. by Manolio, T, Collins, F, Cox, N, Goldstein, D, Hindorff, L, Hunter, D, McCarthy, M, Ramos, E, Cardon, L, Chakravarti, A, Cho, J, Guttmacher, A, Kong, A, Kruglyak, L, Mardis, E, Rotimi, C, Slatkin, M, Valle, D, Whittemore, A, Boehnke, M, Clark, A, Eichler, E, Gibson, G, Haines, J, Mackay, T

Genome-wide association scans identify novel loci that influence lipid levels and risk of coronary artery disease by Najjar, S, Willer, C, Sanna, S, Jackson, A, Arbor, A, Scuteri, A, Clarke, R, Galan, P, Meneton, P, Zelenika, D, Sundvall, J, Watanabe, R, Shuldiner, A, Collins, R, Bergman, R, Uda, M, Tuomilehto, J, Collins, F, Lathrop, G, Boehnke, M, Schlessinger, D, Abecasis, G, Cao, A, Mohlke, K, Lakatta, E

Replicating genotype-phenotype associations. by Chanock, S, Manolio, T, Boehnke, M, Boerwinkle, E, Hunter, D, Thomas, G, Hirschhorn, J, Abecasis, G, Altshuler, D, Bailey-Wilson, J, Brooks, L, Cardon, L, Daly, M, Donnelly, P, Fraumeni, J, Freimer, N, Gerhard, D, Gunter, C, Guttmacher, A, Guyer, MS, Harris, E, Hoh, J, Hoover, R, Kong, C, Merikangas, K

Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. by Yaghootkar, H, Lamina, C, Scott, R, Dastani, Z, Hivert, M, Warren, L, Stancáková, A, Buxbaum, S, Lyytikäinen, L, Henneman, P, Wu, Y, Cheung, C, Pankow, J, Jackson, A, Gustafsson, S, Zhao, J, Ballantyne, C, Xie, W, Bergman, R, Boehnke, M, el Bouazzaoui, F, Collins, F, Dunn, S, Dupuis, J, Forouhi, N

Re-sequencing expands our understanding of the phenotypic impact of variants at GWAS loci by Service, S, Teslovich, T, Fuchsberger, C, Ramensky, V, Yajnik, P, Koboldt, D, Larson, D, Zhang, Q, Lin, L, Welch, R, Ding, L, McLellan, MD, O'Laughlin, M, Fronick, C, Fulton, L, Magrini, V, Swift, A, Elliott, P, Jarvelin, MR, Kaakinen, M, McCarthy, M, Peltonen, L, Pouta, A, Bonnycastle, L, Collins, F, Narisu, N, Stringham, H, Tuomilehto, J, Ripatti, S, Fulton, R, Sabatti, C, Wilson, R, Boehnke, M, Freimer, N

Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D by Viñuela, A, Varshney, A, van de Bunt, M, Prasad, RB, Asplund, O, Bennett, A, Boehnke, M, Brown, AA, Erdos, MR, Fadista, J, Hansson, O, Hatem, G, Howald, C, Iyengar, AK, Johnson, P, Krus, U, MacDonald, PE, Mahajan, A, Manning Fox, JE, Narisu, N, Nylander, V, Orchard, P, Oskolkov, N, Panousis, NI, Payne, A, Stitzel, ML, Vadlamudi, S, Welch, R, Collins, FS, Mohlke, KL, Gloyn, AL, Scott, LJ, Dermitzakis, ET, Groop, L, Parker, SCJ, McCarthy, MI

The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits by Voight, B, Kang, H, Ding, J, Palmer, C, Sidore, C, Chines, P, Burtt, N, Fuchsberger, C, Li, Y, Erdmann, J, Frayling, T, Heid, I, Jackson, A, Johnson, T, Kilpeläinen, T, Lindgren, C, Morris, A, Prokopenko, I, Randall, J, Saxena, R, Soranzo, N, Speliotes, E, Teslovich, T, Wheeler, E, Maguire, J, Parkin, M, Potter, S, Rayner, N, Robertson, N, Stirrups, K, Winckler, W, Sanna, S, Mulas, A, Nagaraja, R, Cucca, F, Barroso, I, Deloukas, P, Loos, R, Kathiresan, S, Munroe, P, Newton-Cheh, C, Pfeufer, A, Samani, N, Schunkert, H, Hirschhorn, J, Altshuler, D, McCarthy, M, Abecasis, G, Boehnke, M

A genome-wide association study of IVGTT-based measures of first phase insulin secretion refines the underlying physiology of Type 2 Diabetes variants. by Wood, A, Jonsson, A, Jackson, A, Wang, N, van Leewen, N, Palmer, N, Kobes, S, Deelen, J, Boquete-Vilarino, L, Paananen, J, Stančáková, A, Boomsma, D, de Geus, E, Eekhoff, E, Fritsche, A, Kramer, M, Nijpels, G, Simonis-Bik, A, van Haeften, T, Mahajan, A, Boehnke, M, Bergman, R, Tuomilehto, J, Collins, F, Mohlke, K, Banasik, K, Groves, C, McCarthy, M, Pearson, E, Natali, A, Mari, A, Buchanan, T, Taylor, K, Xiang, A, Gjesing, A, Grarup, N, Eiberg, H, Pedersen, O, Chen, Y, Laakso, M, Norris, J, Smith, U, Wagenknecht, L, Baier, L, Bowden, D, Hansen, T, Walker, M, Watanabe, R, 't Hart, L, Hanson, R, Frayling, T

Distribution and medical impact of loss-of-function variants in the Finnish founder population by Lim, E, Würtz, P, Havulinna, A, Palta, P, Tukiainen, T, Rehnström, K, Esko, T, Mägi, R, Inouye, M, Lappalainen, T, Chan, Y, Salem, R, Lek, M, Flannick, J, Sim, X, Manning, A, Ladenvall, C, Bumpstead, S, Hämäläinen, E, Aalto, K, Maksimow, M, Salmi, M, Blankenberg, S, Ardissino, D, Shah, S, Horne, B, McPherson, R, Hovingh, G, Reilly, M, Watkins, H, Goel, A, Farrall, M, Girelli, D, Reiner, A, Stitziel, N, Kathiresan, S, Gabriel, S, Barrett, J, Lehtimäki, T, Laakso, M, Groop, L, Kaprio, J, Perola, M, McCarthy, M, Boehnke, M, Altshuler, D, Lindgren, C, Hirschhorn, J, Metspalu, A, Freimer, N, Zeller, T, Jalkanen, S, Koskinen, S, Raitakari, O, Durbin, R, Macarthur, D, Salomaa, V, Ripatti, S, Daly, M, Palotie, A

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. by Keating, B, Tischfield, S, Murray, S, Bhangale, T, Price, T, Glessner, J, Galver, L, Barrett, J, Grant, S, Farlow, D, Chandrupatla, H, Hansen, M, Ajmal, S, Papanicolaou, G, Guo, Y, Li, M, Derohannessian, S, de Bakker, P, Bailey, S, Montpetit, A, Edmondson, A, Taylor, K, Gai, X, Wang, S, Fornage, M, Shaikh, T, Groop, L, Boehnke, M, Hall, A, Hattersley, A, Frackelton, E, Patterson, N, Chiang, C, Kim, C, Fabsitz, R, Ouwehand, W, Price, A, Munroe, P, Caulfield, M, Drake, T, Boerwinkle, E, Reich, D, Whitehead, A, Cappola, T, Samani, N, Lusis, A, Schadt, E, Wilson, J, Koenig, W, McCarthy, M, Kathiresan, S, Gabriel, S, Hakonarson, H, Anand, S, Reilly, M, Engert, J, Nickerson, D, Rader, D, Hirschhorn, J, Fitzgerald, G

Genome-wide characterization of circulating metabolic biomarkers by Karjalainen, MK, Karthikeyan, S, Oliver-Williams, C, Sliz, E, Allara, E, Fung, WT, Surendran, P, Zhang, W, Jousilahti, P, Kristiansson, K, Salomaa, V, Goodwin, M, Hughes, DA, Boehnke, M, Fernandes Silva, L, Yin, X, Mahajan, A, Neville, MJ, van Zuydam, NR, de Mutsert, R, Li-Gao, R, Mook-Kanamori, DO, Demirkan, A, Liu, J, Noordam, R, Trompet, S, Chen, Z, Kartsonaki, C, Li, L, Lin, K, Hagenbeek, FA, Hottenga, JJ, Pool, R, Ikram, MA, van Meurs, J, Haller, T, Milaneschi, Y, Kähönen, M, Mishra, PP, Joshi, PK, Macdonald-Dunlop, E, Mangino, M, Zierer, J, Acar, IE, Hoyng, CB, Lechanteur, YTE, Franke, L, Kurilshikov, A, Zhernakova, A, Beekman, M, Walters, RG, Karpe, F, McCarthy, MI, van Duijn, C, Kettunen, J