Common variants at 6p21.1 are associated with large artery atherosclerotic stroke. by Holliday, E, Maguire, J, Evans, T, Koblar, SA, Jannes, J, Sturm, J, Hankey, G, Baker, R, Golledge, J, Parsons, M, Malik, R, McEvoy, M, Biros, E, Lewis, MD, Lincz, L, Peel, R, Oldmeadow, C, Smith, W, Moscato, P, Barlera, S, Bevan, S, Bis, J, Boerwinkle, E, Boncoraglio, G, Brott, T

The landscape of recombination in African Americans. by Hinch, A, Tandon, A, Patterson, N, Song, Y, Rohland, N, Palmer, C, Chen, G, Wang, K, Buxbaum, S, Akylbekova, E, Aldrich, M, Ambrosone, C, Amos, C, Bandera, E, Berndt, S, Bernstein, L, Blot, W, Bock, C, Boerwinkle, E, Cai, Q, Caporaso, N, Casey, G, Cupples, L, Deming, S, Diver, W

Common variants at 10 genomic loci influence hemoglobin A1C levels via glycemic and nonglycemic pathways (Diabetes (2010) 59, (3229-3239)) by Soranzo, N, Sanna, S, Wheeler, E, Gieger, C, Radke, D, Dupuis, J, Bouatia-Naji, N, Langenberg, C, Prokopenko, I, Stolerman, E, Sandhu, MS, Heeney, M, Devaney, J, Reilly, M, Ricketts, S, Stewart, A, Voight, B, Willenborg, C, Wright, B, Altshuler, D, Arking, D, Balkau, B, Barnes, D, Boerwinkle, E, Böhm, B

Association of exome sequences with plasma C-reactive protein levels in >9000 participants. by Schick, U, Auer, P, Bis, J, Lin, H, Wei, P, Pankratz, N, Lange, L, Brody, J, Stitziel, N, Kim, D, Carlson, C, Fornage, M, Haessler, J, Hsu, L, Jackson, R, Kooperberg, C, Leal, S, Psaty, B, Boerwinkle, E, Tracy, R, Ardissino, D, Shah, S, Willer, C, Loos, R, Melander, O

Replicating genotype-phenotype associations. by Chanock, S, Manolio, T, Boehnke, M, Boerwinkle, E, Hunter, D, Thomas, G, Hirschhorn, J, Abecasis, G, Altshuler, D, Bailey-Wilson, J, Brooks, L, Cardon, L, Daly, M, Donnelly, P, Fraumeni, J, Freimer, N, Gerhard, D, Gunter, C, Guttmacher, A, Guyer, MS, Harris, E, Hoh, J, Hoover, R, Kong, C, Merikangas, K

The landscape of recombination in African Americans by Hinch, A, Tandon, A, Patterson, N, Song, Y, Rohland, N, Palmer, C, Chen, G, Wang, K, Buxbaum, S, Akylbekova, E, Aldrich, M, Ambrosone, C, Amos, C, Bandera, E, Berndt, S, Bernstein, L, Blot, W, Bock, C, Boerwinkle, E, Cai, Q, Caporaso, N, Casey, G, Adrienne Cupples, L, Deming, S, Ryan Diver, W

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels. by Scott, R, Chu, A, Grarup, N, Manning, A, Hivert, M, Shungin, D, Tönjes, A, Yesupriya, A, Barnes, D, Bouatia-Naji, N, Glazer, N, Jackson, A, Kutalik, Z, Lagou, V, Marek, D, Rasmussen-Torvik, L, Stringham, H, Tanaka, T, Aadahl, M, Arking, D, Bergmann, S, Boerwinkle, E, Bonnycastle, L, Bornstein, SR, Brunner, E

Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects by Mishra, A, Chauhan, G, Violleau, M, Vojinovic, D, Jian, X, Bis, J, Li, S, Saba, Y, Grenier-Boley, B, Yang, Q, Bartz, T, Hofer, E, Soumaré, A, Peng, F, Duperron, M, Foglio, M, Mosley, T, Schmidt, R, Psaty, B, Launer, L, Boerwinkle, E, Zhu, Y, Mazoyer, B, Lathrop, M, Bellenguez, C, Van Duijn, C, Ikram, M, Schmidt, H, Longstreth, W, Fornage, M, Seshadri, S, Joutel, A, Tzourio, C, Debette, S

Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels by Tin, A, Li, Y, Brody, J, Nutile, T, Chu, A, Huffman, J, Yang, Q, Chen, M, Robinson-Cohen, C, Macé, A, Liu, J, Demirkan, A, Sorice, R, Sedaghat, S, Swen, M, Yu, B, Ghasemi, S, Teumer, A, Vollenweider, P, Ciullo, M, Li, M, Uitterlinden, A, Kraaij, R, Amin, N, Van Rooij, J, Kutalik, Z, Dehghan, A, McKnight, B, Van Duijn, C, Morrison, A, Psaty, B, Boerwinkle, E, Fox, C, Woodward, O, Köttgen, A

Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways by Young, WJ, Lahrouchi, N, Isaacs, A, Duong, T, Foco, L, Ahmed, F, Brody, JA, Salman, R, Noordam, R, Benjamins, J-W, Haessler, J, Lyytikäinen, L-P, Repetto, L, Concas, MP, van den Berg, ME, Weiss, S, Baldassari, AR, Bartz, TM, Cook, JP, Evans, DS, Freudling, R, Hines, O, Isaksen, JL, Lin, H, Mei, H, Moscati, A, Müller-Nurasyid, M, Nursyifa, C, Qian, Y, Richmond, A, Roselli, C, Ryan, KA, Tarazona-Santos, E, Thériault, S, van Duijvenboden, S, Warren, HR, Yao, J, Raza, D, Aeschbacher, S, Ahlberg, G, Alonso, A, Andreasen, L, Bis, JC, Boerwinkle, E, Campbell, A, Catamo, E, Cocca, M, Cutler, MJ, Darbar, D, De Grandi, A, Morris, AP, van Duijn, CM

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. by Teumer, A, Li, Y, Ghasemi, S, Prins, BP, Wuttke, M, Hermle, T, Giri, A, Sieber, KB, Qiu, C, Kirsten, H, Tin, A, Chu, AY, Bansal, N, Feitosa, MF, Wang, L, Chai, J-F, Cocca, M, Fuchsberger, C, Gorski, M, Hoppmann, A, Horn, K, Li, M, Marten, J, Noce, D, Nutile, T, Sedaghat, S, Sveinbjornsson, G, Tayo, BO, van der Most, PJ, Xu, Y, Yu, Z, Gerstner, L, Ärnlöv, J, Bakker, SJL, Baptista, D, Biggs, ML, Boerwinkle, E, Brenner, H, Burkhardt, R, Carroll, RJ, Chee, M-L, Chee, M-L, Chen, M, Cheng, C-Y, Cook, JP, Coresh, J, Corre, T, Danesh, J, de Borst, MH, De Grandi, A, Lindgren, CM

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. by Keating, B, Tischfield, S, Murray, S, Bhangale, T, Price, T, Glessner, J, Galver, L, Barrett, J, Grant, S, Farlow, D, Chandrupatla, H, Hansen, M, Ajmal, S, Papanicolaou, G, Guo, Y, Li, M, Derohannessian, S, de Bakker, P, Bailey, S, Montpetit, A, Edmondson, A, Taylor, K, Gai, X, Wang, S, Fornage, M, Shaikh, T, Groop, L, Boehnke, M, Hall, A, Hattersley, A, Frackelton, E, Patterson, N, Chiang, C, Kim, C, Fabsitz, R, Ouwehand, W, Price, A, Munroe, P, Caulfield, M, Drake, T, Boerwinkle, E, Reich, D, Whitehead, A, Cappola, T, Samani, N, Lusis, A, Schadt, E, Wilson, J, Koenig, W, McCarthy, M, Kathiresan, S, Gabriel, S, Hakonarson, H, Anand, S, Reilly, M, Engert, J, Nickerson, D, Rader, D, Hirschhorn, J, Fitzgerald, G

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. by Perry, JR, Voight, B, Yengo, L, Amin, N, Dupuis, J, Ganser, M, Grallert, H, Navarro, P, Li, M, Qi, L, Steinthorsdottir, V, Scott, R, Almgren, P, Arking, D, Aulchenko, Y, Balkau, B, Benediktsson, R, Bergman, R, Boerwinkle, E, Bonnycastle, L, Burtt, N, Campbell, H, Charpentier, G, Collins, F, Gieger, C, Green, T, Hadjadj, S, Hattersley, A, Herder, C, Hofman, A, Johnson, A, Kottgen, A, Kraft, P, Labrune, Y, Langenberg, C, Manning, A, Mohlke, K, Morris, A, Oostra, B, Pankow, J, Petersen, A, Pramstaller, P, Prokopenko, I, Rathmann, W, Rayner, W, Roden, M, Rudan, I, Rybin, D, Scott, L, Sigurdsson, G, Sladek, R, Thorleifsson, G, Thorsteinsdottir, U, Tuomilehto, J, Uitterlinden, A, Vivequin, S, Weedon, M, Wright, A, Hu, F, Illig, T, Kao, L, Meigs, J, Wilson, J, Stefansson, K, van Duijn, C, Altschuler, D, Morris, A, Boehnke, M, McCarthy, M, Froguel, P, Palmer, C, Wareham, N, Groop, L, Frayling, T, Cauchi, S

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins by Postmus, I, Warren, HR, Trompet, S, Arsenault, BJ, Avery, CL, Bis, JC, Chasman, DI, De Keyser, CE, Deshmukh, HA, Evans, DS, Feng, Q, Li, X, Smit, RAJ, Smith, AV, Sun, F, Taylor, KD, Arnold, AM, Barnes, MR, Barratt, BJ, Betteridge, J, Boekholdt, SM, Boerwinkle, E, Buckley, BM, Chen, Y-DI, De Craen, AJM, Cummings, SR, Denny, JC, Dubé, MP, Durrington, PN, Eiriksdottir, G, Ford, I, Guo, X, Harris, TB, Heckbert, SR, Hofman, A, Hovingh, GK, Kastelein, JJP, Launer, LJ, Liu, C-T, Liu, Y, Lumley, T, McKeigue, PM, Munroe, PB, Neil, A, Nickerson, DA, Nyberg, F, O'Brien, E, O'Donnell, CJ, Post, W, Poulter, N, Vasan, RS, Rice, K, Rich, SS, Rivadeneira, F, Sattar, N, Sever, P, Shaw-Hawkins, S, Shields, DC, Slagboom, PE, Smith, NL, Smith, JD, Sotoodehnia, N, Stanton, A, Stott, DJ, Stricker, BH, Stürmer, T, Uitterlinden, AG, Wei, W-Q, Westendorp, RGJ, Whitsel, EA, Wiggins, KL, Wilke, RA, Ballantyne, CM, Colhoun, HM, Cupples, LA, Franco, OH, Gudnason, V, Hitman, G, Palmer, CNA, Psaty, BM, Ridker, PM, Stafford, JM, Stein, CM, Tardif, J-C, Caulfield, MJ, Jukema, JW, Rotter, JI, Krauss, RM

No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects by Baumert, J, Huang, J, McKnight, B, Sabater-Lleal, M, Steri, M, Chu, A, Trompet, S, Lopez, L, Fornage, M, Teumer, A, Tang, W, Rudnicka, A, Mälarstig, A, Hottenga, J, Kavousi, M, Lahti, J, Tanaka, T, Hayward, C, Huffman, J, Morange, P, Rose, L, Basu, S, Rumley, A, Stott, D, Buckley, B, De Craen, A, Sanna, S, Masala, M, Biffar, R, Homuth, G, Silveira, A, Sennblad, B, Goel, A, Watkins, H, Müller-Nurasyid, M, Rückerl, R, Taylor, K, Chen, M, De Geus, E, Hofman, A, Witteman, J, Maat, D, Palotie, A, Davies, G, Siscovick, D, Kolcic, I, Wild, S, Song, J, McArdle, W, Ford, I, Sattar, N, Schlessinger, D, Grotevendt, A, Franzosi, MG, Illig, T, Waldenberger, M, Lumley, T, Tofler, G, Willemsen, G, Uitterlinden, A, Rivadeneira, F, Räikkönen, K, Chasman, D, Folsom, A, Lowe, G, Westendorp, R, Slagboom, P, Cucca, F, Wallaschofski, H, Strawbridge, R, Seedorf, U, Koenig, W, Bis, J, Mukamal, K, Van Dongen, J, Widen, E, Franco, O, Starr, J, Liu, K, Ferrucci, L, Polasek, O, Wilson, J, Oudot-Mellakh, T, Campbell, H, Navarro, P, Bandinelli, S, Eriksson, J, Boomsma, D, Dehghan, A, Clarke, R, Hamsten, A, Boerwinkle, E, Jukema, J, Naitza, S, Ridker, P, Völzke, H, Deary, I, Reiner, A, Trégouët, D, O'Donnell, C, Strachan, D, Peters, A, Smith, N

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins by Postmus, I, Trompet, S, Deshmukh, H, Barnes, MR, Li, X, Warren, H, Chasman, D, Zhou, K, Arsenault, B, Donnelly, L, Wiggins, K, Avery, C, Griffin, P, Feng, Q, Taylor, K, Li, G, Evans, D, Smith, A, De Keyser, C, Johnson, A, De Craen, A, Stott, D, Buckley, B, Ford, I, Westendorp, R, Slagboom, P, Sattar, N, Munroe, P, Sever, P, Poulter, N, Stanton, A, Shields, D, O'Brien, E, Shaw-Hawkins, S, Chen, Y, Nickerson, D, Smith, J, Dubé, M, Boekholdt, S, Hovingh, G, Kastelein, J, McKeigue, P, Betteridge, J, Neil, A, Durrington, P, Doney, A, Carr, F, Morris, A, McCarthy, M, Groop, L, Ahlqvist, E, Bis, J, Rice, K, Smith, N, Lumley, T, Whitsel, E, Stürmer, T, Boerwinkle, E, Ngwa, J, O'Donnell, C, Vasan, R, Wei, W, Wilke, R, Liu, C, Sun, F, Guo, X, Heckbert, SR, Post, W, Sotoodehnia, N, Arnold, A, Stafford, J, Ding, J, Herrington, D, Kritchevsky, S, Eiriksdottir, G, Launer, L, Harris, T, Chu, A, Giulianini, F, Macfadyen, J, Barratt, B, Nyberg, F, Stricker, B, Uitterlinden, A, Hofman, A, Rivadeneira, F, Emilsson, V, Franco, O, Ridker, P, Gudnason, V, Liu, Y, Denny, J, Ballantyne, C, Rotter, J, Adrienne Cupples, L, Psaty, B, Palmer, C, Tardif, J, Colhoun, H, Hitman, G, Krauss, R, Wouter Jukema, J, Caulfield, M, Wellcome Trust Case Control Consortium

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. by Jiang, X, O'Reilly, PF, Aschard, H, Hsu, Y-H, Richards, JB, Dupuis, J, Ingelsson, E, Karasik, D, Pilz, S, Berry, D, Kestenbaum, B, Zheng, J, Luan, J, Sofianopoulou, E, Streeten, EA, Albanes, D, Lutsey, PL, Yao, L, Tang, W, Econs, MJ, Wallaschofski, H, Völzke, H, Zhou, A, Power, C, McCarthy, MI, Michos, ED, Boerwinkle, E, Weinstein, SJ, Freedman, ND, Huang, W-Y, Van Schoor, NM, van der Velde, N, Groot, LCPGMD, Booth, SL, Vasan, RS, Liu, C-T, Zhou, Y, Ripatti, S, Ohlsson, C, Eriksson, JG, Shea, MK, Houston, DK, Kritchevsky, SB, Liu, Y, Lohman, KK, Ferrucci, L, Peacock, M, Gieger, C, Beekman, M, Slagboom, E, Deelen, J, Heemst, DV, Kleber, ME, März, W, de Boer, IH, Wood, AC, Rotter, JI, Rich, SS, Robinson-Cohen, C, Heijer, M, Jarvelin, M-R, Cavadino, A, Joshi, PK, Wilson, JF, Hayward, C, Lind, L, Michaëlsson, K, Trompet, S, Zillikens, MC, Uitterlinden, AG, Rivadeneira, F, Broer, L, Zgaga, L, Campbell, H, Theodoratou, E, Farrington, SM, Timofeeva, M, Dunlop, MG, Valdes, AM, Tikkanen, E, Lehtimäki, T, Lyytikäinen, L-P, Kähönen, M, Raitakari, OT, Mikkilä, V, Ikram, MA, Sattar, N, Jukema, JW, Wareham, NJ, Langenberg, C, Forouhi, NG, Gundersen, TE, Khaw, K-T, Butterworth, AS, Danesh, J, Spector, T, Wang, TJ, Hyppönen, E, Kraft, P, Kiel, DP

Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. by Lange, L, Hu, Y, Zhang, H, Xue, C, Schmidt, E, Tang, Z, Bizon, C, Lange, E, Smith, J, Turner, E, Jun, G, Kang, H, Peloso, G, Auer, P, Li, K, Flannick, J, Zhang, J, Fuchsberger, C, Gaulton, K, Lindgren, C, Locke, A, Manning, A, Sim, X, Rivas, M, Holmen, O, Gottesman, O, Lu, Y, Ruderfer, D, Stahl, E, Duan, Q, Li, Y, Durda, P, Jiao, S, Isaacs, A, Hofman, A, Bis, J, Correa, A, Griswold, M, Jakobsdottir, J, Smith, A, Schreiner, P, Feitosa, M, Zhang, Q, Huffman, J, Crosby, J, Wassel, C, Do, R, Franceschini, N, Martin, L, Robinson, J, Assimes, T, Crosslin, DR, Rosenthal, E, Tsai, M, Rieder, M, Farlow, D, Folsom, A, Lumley, T, Fox, E, Carlson, C, Peters, U, Jackson, R, van Duijn, C, Uitterlinden, A, Levy, D, Rotter, J, Taylor, H, Gudnason, V, Siscovick, D, Fornage, M, Borecki, I, Hayward, C, Rudan, I, Chen, Y, Bottinger, E, Loos, R, Sætrom, P, Hveem, K, Boehnke, M, Groop, L, McCarthy, M, Meitinger, T, Ballantyne, C, Gabriel, S, O'Donnell, C, Post, W, North, K, Reiner, A, Boerwinkle, E, Psaty, B, Altshuler, D, Kathiresan, S, Lin, D, Jarvik, G, Cupples, L, Kooperberg, C, Wilson, J, Nickerson, D, Abecasis, G, Rich, S, Tracy, R, Willer, C

Genome-wide trans-ethnic meta-analysis identifies seven genetic loci influencing erythrocyte traits and a role for RBPMS in erythropoiesis by van Rooij, FJ, Qayyum, R, Smith, AV, Zhou, Y, Trompet, S, Tanaka, T, Keller, MF, Chang, LC, Schmidt, H, Yang, ML, Chen, MH, Hayes, J, Johnson, AD, Yanek, LR, Mueller, C, Lange, L, Floyd, JS, Ghanbari, M, Zonderman, AB, Jukema, JW, Hofman, A, van Duijn, CM, Desch, KC, Saba, Y, Ozel, AB, Snively, BM, Wu, JY, Schmidt, R, Fornage, M, Klein, RJ, Fox, CS, Matsuda, K, Kamatani, N, Wild, PS, Stott, DJ, Ford, I, Slagboom, PE, Yang, J, Chu, AY, Lambert, AJ, Uitterlinden, AG, Franco, OH, Hofer, E, Ginsburg, D, Hu, B, Keating, B, Schick, UM, Brody, JA, Li, JZ, Chen, Z, Zeller, T, Guralnik, JM, Chasman, DI, Peters, LL, Kubo, M, Becker, DM, Li, J, Eiriksdottir, G, Rotter, JI, Levy, D, Grossmann, V, Patel, KV, Chen, CH, BioBank Japan Project, Ridker, PM, Tang, H, Launer, LJ, Rice, KM, Li-Gao, R, Ferrucci, L, Evans, MK, Choudhuri, A, Trompouki, E, Abraham, BJ, Yang, S, Takahashi, A, Kamatani, Y, Kooperberg, C, Harris, TB, Jee, SH, Coresh, J, Tsai, FJ, Longo, DL, Chen, YT, Felix, JF, Yang, Q, Psaty, BM, Boerwinkle, E, Becker, LC, Mook-Kanamori, DO, Wilson, JG, Gudnason, V, O'Donnell, CJ, Dehghan, A, Cupples, LA, Nalls, MA, Morris, AP, Okada, Y, Reiner, AP, Zon, LI, Ganesh, SK

Trans-ethnic meta-analysis and functional annotation illuminates the genetic architecture of fasting glucose and insulin by Liu, C, Raghavan, S, Maruthur, N, Kabagambe, E, Hong, J, Ng, M, Hivert, M, Lu, Y, An, P, Bentley, A, Drolet, A, Gaulton, K, Guo, X, Armstrong, L, Irvin, M, Li, M, Lipovich, L, Rybin, D, Taylor, K, Agyemang, C, Palmer, N, Cade, B, Chen, W, Dauriz, M, Delaney, J, Edwards, T, Evans, D, Evans, M, Lange, L, Leong, A, Liu, J, Liu, Y, Nayak, U, Patel, S, Porneala, B, Rasmussen-Torvik, L, Snijder, M, Stallings, S, Tanaka, T, Yanek, L, Zhao, W, Becker, D, Bielak, L, Biggs, M, Bottinger, E, Bowden, D, Chen, G, Correa, A, Couper, D, Crawford, D, Cushman, M, Eicher, J, Fornage, M, Franceschini, N, Fu, Y, Goodarzi, M, Gottesman, O, Hara, K, Harris, T, Jensen, R, Johnson, A, Jhun, M, Karter, A, Keller, M, Kho, A, Kizer, J, Krauss, R, Langefeld, C, Li, X, Liang, J, Liu, S, Lowe, W, Mosley, T, North, K, Pacheco, J, Peyser, P, Patrick, A, Rice, K, Selvin, E, Sims, M, Smith, J, Tajuddin, S, Vaidya, D, Wren, M, Yao, J, Zhu, X, Ziegler, J, Zmuda, J, Zonderman, A, Zwinderman, A, Adeyemo, A, Boerwinkle, E, Ferrucci, L, Hayes, M, Kardia, S, Miljkovic, I, Pankow, J, Rotimi, C, Sale, M, Wagenknecht, L, Arnett, D, Chen, Y, Nalls, M, Province, M, Kao, W, Siscovick, D, Psaty, B, Wilson, J, Loos, R, Dupuis, J, Rich, S, Florez, J, Rotter, J, Morris, A, Meigs, J