The Impact of Acute or Chronic Alcohol Intake on the NF-κB Signaling Pathway in Alcohol-Related Liver Disease by Aleksander J. Nowak, Borna Relja

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Utilizing predictive machine-learning modelling unveils feature-based risk assessment system for hyperinflammatory patterns and infectious outcomes in polytrauma by Melanie Fachet, Raghava Vinaykanth Mushunuri, Christian B. Bergmann, Ingo Marzi, Christoph Hoeschen, Borna Relja, Borna Relja

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Is I-FABP not only a marker for the detection abdominal injury but also of hemorrhagic shock in severely injured trauma patients? by Maika Voth, Thomas Lustenberger, Borna Relja, Ingo Marzi

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Post-Traumatic Sepsis Is Associated with Increased C5a and Decreased TAFI Levels by Jan Tilmann Vollrath, Ingo Marzi, Anna Herminghaus, Thomas Lustenberger, Borna Relja

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Editorial: Community series in translational insights into mechanisms and therapy of organ dysfunction in sepsis and trauma, volume II by Borna Relja, Sina Maren Coldewey, Pietro Ghezzi, Lukas Martin, Christoph Thiemermann

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Acute Alcohol Intoxication Modulates Monocyte Subsets and Their Functions in a Time-Dependent Manner in Healthy Volunteers by Andrea Janicova, Florian Haag, Baolin Xu, Alejandra P. Garza, Ildiko Rita Dunay, Claudia Neunaber, Aleksander J. Nowak, Paola Cavalli, Ingo Marzi, Ramona Sturm, Borna Relja, Borna Relja

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Trauma Severity and Its Impact on Local Inflammation in Extremity Injury—Insights From a Combined Trauma Model in Pigs by Klemens Horst, Klemens Horst, Johannes Greven, Johannes Greven, Hannah Lüken, Qiao Zhi, Roman Pfeifer, Tim P. Simon, Borna Relja, Borna Relja, Ingo Marzi, Hans-Christoph Pape, Frank Hildebrand

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CoNiCrMo Particles, but Not TiAlV Particles, Activate the NLRP3 Inflammasome in Periprosthetic Cells by Fenna Brunken, Tristan Senft, Maria Herbster, Borna Relja, Jessica Bertrand, Christoph H. Lohmann

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Selective Internal Radiotherapy Alters the Profiles of Systemic Extracellular Vesicles in Hepatocellular Carcinoma by Severin Gylstorff, Vanessa Wilke, Daniel Kraft, Jessica Bertrand, Maciej Pech, Florian Haag, Borna Relja

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Curcumin—A Viable Agent for Better Bladder Cancer Treatment by Jochen Rutz, Andrea Janicova, Katja Woidacki, Felix K.-H. Chun, Roman A. Blaheta, Borna Relja

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Selective Inhibition of IL-6 Trans-Signaling Has No Beneficial Effect on the Posttraumatic Cytokine Release after Multiple Trauma in Mice by Jil-Madeline Homeier, Katrin Bundkirchen, Marcel Winkelmann, Tilman Graulich, Borna Relja, Claudia Neunaber, Christian Macke

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Fracture Healing in Elderly Mice and the Effect of an Additional Severe Blood Loss: A Radiographic and Biomechanical Murine Study by Katrin Bundkirchen, Weikang Ye, Aleksander J. Nowak, Stefan Lienenklaus, Bastian Welke, Borna Relja, Claudia Neunaber

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A Barrier to Defend - Models of Pulmonary Barrier to Study Acute Inflammatory Diseases by Anna Herminghaus, Andrey V. Kozlov, Andrey V. Kozlov, Andrea Szabó, Zoltán Hantos, Severin Gylstorff, Severin Gylstorff, Anne Kuebart, Mahyar Aghapour, Bianka Wissuwa, Thorsten Walles, Heike Walles, Heike Walles, Sina M. Coldewey, Borna Relja, Borna Relja

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Differential Relevance of NF-κB and JNK in the Pathophysiology of Hemorrhage/Resususcitation-Induced Liver Injury after Chronic Ethanol Feeding. by Borna Relja, Roxane Weber, Miriam Maraslioglu, Nils Wagner, Tiziana Borsello, Christian Jobin, Ingo Marzi, Mark Lehnert

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Regulatory T Cells Modulate CD4 Proliferation after Severe Trauma via IL-10 by Ramona Sturm, Lara Xanthopoulos, David Heftrig, Elsie Oppermann, Teodora Vrdoljak, Ildiko Rita Dunay, Ingo Marzi, Borna Relja

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Indomethacin Increases the Efficacy of Oxygen Utilization of Colonic Mitochondria and Uncouples Hepatic Mitochondria in Tissue Homogenates From Healthy Rats by Anna Herminghaus, Albert J. Buitenhuis, Jan Schulz, Richard Truse, Christian Vollmer, Borna Relja, Inge Bauer, Olaf Picker

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Serum α-1 Antitrypsin (AAT) antagonizes intrinsic apoptosis induction in neutrophils from patients with systemic inflammatory response syndrome. by Theresia Sarabhai, Christoph Peter, Anne-Kathrin Bär, Joachim Windolf, Borna Relja, Sebastian Wesselborg, Thorsten Wahlers, Adnana Paunel-Görgülü

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Diffusion-Weighted Imaging Reflects Tumor Grading and Microvascular Invasion in Hepatocellular Carcinoma by Alexey Surov, Maciej Pech, Jazan Omari, Frank Fischbach, Robert Damm, Katharina Fischbach, Maciej Powerski, Borna Relja, Andreas Wienke

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Nanoplastics affect the inflammatory cytokine release by primary human monocytes and dendritic cells by Annkatrin Weber, Anja Schwiebs, Helene Solhaug, Jørgen Stenvik, Asbjørn M. Nilsen, Martin Wagner, Borna Relja, Heinfried H. Radeke

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Effects of Circulating HMGB-1 and Histones on Cardiomyocytes–Hemadsorption of These DAMPs as Therapeutic Strategy after Multiple Trauma by Birte Weber, Ina Lackner, Meike Baur, Giorgio Fois, Florian Gebhard, Ingo Marzi, Hubert Schrezenmeier, Borna Relja, Miriam Kalbitz

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